cimetidine has been researched along with Smoking Cessation in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Smoking Cessation: Discontinuing the habit of SMOKING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Varenicline was characterized as a moderate-affinity substrate for hOCT2 (K(m)=370 microM) and its hOCT2-mediated uptake was partially inhibited by cimetidine." | 6.73 | Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. ( Burstein, AH; Clark, DJ; de Morais, SM; Faessel, HM; Feng, B; Obach, RS, 2008) |
| "Varenicline was characterized as a moderate-affinity substrate for hOCT2 (K(m)=370 microM) and its hOCT2-mediated uptake was partially inhibited by cimetidine." | 2.73 | Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. ( Burstein, AH; Clark, DJ; de Morais, SM; Faessel, HM; Feng, B; Obach, RS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, B | 1 |
| Obach, RS | 1 |
| Burstein, AH | 1 |
| Clark, DJ | 1 |
| de Morais, SM | 1 |
| Faessel, HM | 1 |
| Bendayan, R | 1 |
| Kennedy, G | 1 |
| Frecker, RC | 1 |
| Sellers, EM | 1 |
2 trials available for cimetidine and Smoking Cessation
| Article | Year |
|---|---|
Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.
Topics: Adult; Benzazepines; Chromatography, High Pressure Liquid; Cimetidine; Embryo, Mammalian; Enzyme Inh | 2008 |
Lack of effect of cimetidine on cigarette smoking.
Topics: Carbon Monoxide; Cimetidine; Cotinine; Double-Blind Method; Female; Humans; Male; Nicotine; Smoking; | 1993 |