cimetidine has been researched along with Serotonin Syndrome in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The serotonin toxicity (ST) is a potentially life-threatening adverse drug reaction results from therapeutic drug use, intentional self-poisoning, or inadvertent interactions between drugs." | 2.47 | Serotonin toxicity: a short review of the literature and two case reports involving citalopram. ( Bruno, G; Canevelli, M; Lenzi, GL; Piacentini, E; Pietracupa, S; Talarico, G; Tosto, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Talarico, G | 1 |
| Tosto, G | 1 |
| Pietracupa, S | 1 |
| Piacentini, E | 1 |
| Canevelli, M | 1 |
| Lenzi, GL | 1 |
| Bruno, G | 1 |
1 review available for cimetidine and Serotonin Syndrome
| Article | Year |
|---|---|
Serotonin toxicity: a short review of the literature and two case reports involving citalopram.
Topics: Aged; Cimetidine; Citalopram; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Female; F | 2011 |