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cimetidine and Sclerosis, Systemic

cimetidine has been researched along with Sclerosis, Systemic in 7 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Treatment with cimetidine caused the remission of cutaneous manifestations and the extracutaneous abnormalities, such as nailfold capillary disturbances and the presence of antithyroid antibodies, improved."5.28Treatment with cimetidine of atypical fasciitis panniculitis syndrome. ( Abrahamson, JE; Boss, JH; Misselevitch, I; Naschitz, JE; Rosner, I; Yeshurun, D, 1990)
"Cimetidine was without toxicity whereas antacid therapy frequently produced diarrhea."2.65Cimetidine versus antacid in scleroderma with reflux esophagitis. A randomized double-blind controlled study. ( Jeffries, GH; Petrokubi, RJ, 1979)
"Treatment with cimetidine caused the remission of cutaneous manifestations and the extracutaneous abnormalities, such as nailfold capillary disturbances and the presence of antithyroid antibodies, improved."1.28Treatment with cimetidine of atypical fasciitis panniculitis syndrome. ( Abrahamson, JE; Boss, JH; Misselevitch, I; Naschitz, JE; Rosner, I; Yeshurun, D, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Modena, S1
Crudo, V1
Abrescia, F1
Baratella, M1
Bertrand, C1
Salvagno, R1
Vesentini, S1
Kikuchi, K1
Kadono, T1
Fujimoto, M1
Ihn, H1
Sato, S1
Takehara, K1
Horikoshi, T1
Matsuzaki, T1
Sekiguchi, T1
Petrokubi, RJ1
Jeffries, GH1
Abshire, SG1
Dement, LN1
Ferrante, WA1
Hines, C1
Sciallis, GF1
Levenson, H1
Naschitz, JE1
Yeshurun, D1
Rosner, I1
Abrahamson, JE1
Misselevitch, I1
Boss, JH1

Trials

2 trials available for cimetidine and Sclerosis, Systemic

ArticleYear
Effect of H2-receptor antagonists cimetidine and famotidine on interdigestive gastric motor activity and lower esophageal sphincter pressure in progressive systemic sclerosis.
    Internal medicine (Tokyo, Japan), 1994, Volume: 33, Issue:7

    Topics: Cimetidine; Esophagogastric Junction; Famotidine; Female; Gastrointestinal Motility; Humans; Injecti

1994
Cimetidine versus antacid in scleroderma with reflux esophagitis. A randomized double-blind controlled study.
    Gastroenterology, 1979, Volume: 77, Issue:4 Pt 1

    Topics: Adult; Antacids; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Esophagitis, Peptic; Eso

1979

Other Studies

5 other studies available for cimetidine and Sclerosis, Systemic

ArticleYear
[Esophago-gastro-enteric manifestations of scleroderma. Apropos of a clinical case].
    Chirurgia italiana, 1983, Volume: 35, Issue:2

    Topics: Adult; Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Esophageal Diseases; Gastroesophageal Re

1983
Elevated procollagen type I carboxyterminal propeptide production in cultured scleroderma fibroblasts.
    Dermatology (Basel, Switzerland), 1995, Volume: 190, Issue:2

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Cells, Cultured; Chlorpheniramine; Cimetidine; Collag

1995
Cimetidine in the treatment of esophagitis associated with autoimmune diseases.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1979, Volume: 131, Issue:2

    Topics: Adult; Autoimmune Diseases; Cimetidine; Esophagitis, Peptic; Female; Guanidines; Humans; Middle Aged

1979
Cimetidine in scleroderma.
    Archives of dermatology, 1979, Volume: 115, Issue:9

    Topics: Cimetidine; Esophagitis, Peptic; Guanidines; Humans; Male; Middle Aged; Scleroderma, Systemic

1979
Treatment with cimetidine of atypical fasciitis panniculitis syndrome.
    Annals of the rheumatic diseases, 1990, Volume: 49, Issue:10

    Topics: Adult; Aged; Cimetidine; Eosinophilia; Fasciitis; Female; Humans; Male; Middle Aged; Panniculitis; P

1990