cimetidine has been researched along with Sclerosis, Systemic in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with cimetidine caused the remission of cutaneous manifestations and the extracutaneous abnormalities, such as nailfold capillary disturbances and the presence of antithyroid antibodies, improved." | 5.28 | Treatment with cimetidine of atypical fasciitis panniculitis syndrome. ( Abrahamson, JE; Boss, JH; Misselevitch, I; Naschitz, JE; Rosner, I; Yeshurun, D, 1990) |
| "Cimetidine was without toxicity whereas antacid therapy frequently produced diarrhea." | 2.65 | Cimetidine versus antacid in scleroderma with reflux esophagitis. A randomized double-blind controlled study. ( Jeffries, GH; Petrokubi, RJ, 1979) |
| "Treatment with cimetidine caused the remission of cutaneous manifestations and the extracutaneous abnormalities, such as nailfold capillary disturbances and the presence of antithyroid antibodies, improved." | 1.28 | Treatment with cimetidine of atypical fasciitis panniculitis syndrome. ( Abrahamson, JE; Boss, JH; Misselevitch, I; Naschitz, JE; Rosner, I; Yeshurun, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Modena, S | 1 |
| Crudo, V | 1 |
| Abrescia, F | 1 |
| Baratella, M | 1 |
| Bertrand, C | 1 |
| Salvagno, R | 1 |
| Vesentini, S | 1 |
| Kikuchi, K | 1 |
| Kadono, T | 1 |
| Fujimoto, M | 1 |
| Ihn, H | 1 |
| Sato, S | 1 |
| Takehara, K | 1 |
| Horikoshi, T | 1 |
| Matsuzaki, T | 1 |
| Sekiguchi, T | 1 |
| Petrokubi, RJ | 1 |
| Jeffries, GH | 1 |
| Abshire, SG | 1 |
| Dement, LN | 1 |
| Ferrante, WA | 1 |
| Hines, C | 1 |
| Sciallis, GF | 1 |
| Levenson, H | 1 |
| Naschitz, JE | 1 |
| Yeshurun, D | 1 |
| Rosner, I | 1 |
| Abrahamson, JE | 1 |
| Misselevitch, I | 1 |
| Boss, JH | 1 |
2 trials available for cimetidine and Sclerosis, Systemic
| Article | Year |
|---|---|
Effect of H2-receptor antagonists cimetidine and famotidine on interdigestive gastric motor activity and lower esophageal sphincter pressure in progressive systemic sclerosis.
Topics: Cimetidine; Esophagogastric Junction; Famotidine; Female; Gastrointestinal Motility; Humans; Injecti | 1994 |
Cimetidine versus antacid in scleroderma with reflux esophagitis. A randomized double-blind controlled study.
Topics: Adult; Antacids; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Esophagitis, Peptic; Eso | 1979 |
5 other studies available for cimetidine and Sclerosis, Systemic
| Article | Year |
|---|---|
[Esophago-gastro-enteric manifestations of scleroderma. Apropos of a clinical case].
Topics: Adult; Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Esophageal Diseases; Gastroesophageal Re | 1983 |
Elevated procollagen type I carboxyterminal propeptide production in cultured scleroderma fibroblasts.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Cells, Cultured; Chlorpheniramine; Cimetidine; Collag | 1995 |
Cimetidine in the treatment of esophagitis associated with autoimmune diseases.
Topics: Adult; Autoimmune Diseases; Cimetidine; Esophagitis, Peptic; Female; Guanidines; Humans; Middle Aged | 1979 |
Cimetidine in scleroderma.
Topics: Cimetidine; Esophagitis, Peptic; Guanidines; Humans; Male; Middle Aged; Scleroderma, Systemic | 1979 |
Treatment with cimetidine of atypical fasciitis panniculitis syndrome.
Topics: Adult; Aged; Cimetidine; Eosinophilia; Fasciitis; Female; Humans; Male; Middle Aged; Panniculitis; P | 1990 |