cimetidine has been researched along with Scleroderma, Localized in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Scleroderma, Localized: A term used to describe a variety of localized asymmetrical SKIN thickening that is similar to those of SYSTEMIC SCLERODERMA but without the disease features in the multiple internal organs and BLOOD VESSELS. Lesions may be characterized as patches or plaques (morphea), bands (linear), or nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The histological features of lipodermatosclerosis and eosinophilic fasciitis and its variants were compared in a prospective study of outpatients attending the vascular clinic and inpatients in the Department of Medicine of a regional university hospital." | 1.29 | Pathogenesis of lipodermatosclerosis of venous disease: the lesson learned from eosinophilic fasciitis. ( Boss, JH; Croitoru, S; Misselevich, I; Naschitz, JE; Schwartz, H; Shajrawi, I; Yeshurun, D, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kikuchi, K | 1 |
| Kadono, T | 1 |
| Fujimoto, M | 1 |
| Ihn, H | 1 |
| Sato, S | 1 |
| Takehara, K | 1 |
| Naschitz, JE | 1 |
| Yeshurun, D | 1 |
| Schwartz, H | 1 |
| Croitoru, S | 1 |
| Shajrawi, I | 1 |
| Misselevich, I | 1 |
| Boss, JH | 1 |
2 other studies available for cimetidine and Scleroderma, Localized
| Article | Year |
|---|---|
Elevated procollagen type I carboxyterminal propeptide production in cultured scleroderma fibroblasts.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Cells, Cultured; Chlorpheniramine; Cimetidine; Collag | 1995 |
Pathogenesis of lipodermatosclerosis of venous disease: the lesson learned from eosinophilic fasciitis.
Topics: Adipose Tissue; Aged; Cimetidine; Collagen; Eosinophilia; Fascia; Fasciitis; Female; Fibrosis; Human | 1993 |