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cimetidine and Schistosomiasis

cimetidine has been researched along with Schistosomiasis in 5 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.

Research Excerpts

ExcerptRelevanceReference
"The effect of histamine on cell-mediated immune responses of chronic schistosomiasis patients was tested by peripheral blood mononuclear cell (PBMN) reactions to phytohemagglutinin-P (PHA) and soluble schistosomal antigenic preparations derived from eggs (SEA) or adult worms (SWAP)."7.67Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis. ( Barsoum, IS; Colley, DG; Dahawi, HS; El Alamy, MA; Gamil, FM; Habib, M, 1984)
"The effect of histamine on cell-mediated immune responses of chronic schistosomiasis patients was tested by peripheral blood mononuclear cell (PBMN) reactions to phytohemagglutinin-P (PHA) and soluble schistosomal antigenic preparations derived from eggs (SEA) or adult worms (SWAP)."3.67Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis. ( Barsoum, IS; Colley, DG; Dahawi, HS; El Alamy, MA; Gamil, FM; Habib, M, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weinstock, JV3
Boros, DL3
Barsoum, IS1
Dahawi, HS1
Gamil, FM1
Habib, M1
El Alamy, MA1
Colley, DG1
Chensue, SW1
el Hawy, AM1
Negm, IA1
el-Rakaybe, A1
Abdel-Maged, AI1
Mansour, RE1

Other Studies

5 other studies available for cimetidine and Schistosomiasis

ArticleYear
Alteration of granuloma angiotensin I-converting enzyme activity by regulatory T lymphocytes in murine schistosomiasis.
    Infection and immunity, 1982, Volume: 35, Issue:2

    Topics: Animals; Cimetidine; Cyclophosphamide; Female; Granuloma; Liver; Macrophages; Mice; Mice, Inbred CBA

1982
Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis.
    Journal of immunology (Baltimore, Md. : 1950), 1984, Volume: 133, Issue:3

    Topics: Adult; Antigens; Cimetidine; Egypt; Female; Histamine; Humans; Immunosuppressive Agents; Larva; Lymp

1984
Modulation of granulomatous hypersensitivity. V. Participation of histamine receptor positive and negative lymphocytes in the granulomatous response of Schistosoma mansoni-infected mice.
    Journal of immunology (Baltimore, Md. : 1950), 1983, Volume: 130, Issue:1

    Topics: Animals; Cell Migration Inhibition; Cimetidine; Diphenhydramine; Immune Tolerance; Liver; Lymphomato

1983
Heterogeneity of the granulomatous response in the liver, colon, ileum, and ileal Peyer's patches to schistosome eggs in murine schistosomiasis mansoni.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 127, Issue:5

    Topics: Animals; Antilymphocyte Serum; Chronic Disease; Cimetidine; Colon; Complement System Proteins; Cyclo

1981
The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
    Journal of the Egyptian Society of Parasitology, 1993, Volume: 23, Issue:1

    Topics: Blood Pressure; Cimetidine; Humans; Hypertension, Pulmonary; Nifedipine; Random Allocation; Schistos

1993