cimetidine has been researched along with Schistosomiasis in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of histamine on cell-mediated immune responses of chronic schistosomiasis patients was tested by peripheral blood mononuclear cell (PBMN) reactions to phytohemagglutinin-P (PHA) and soluble schistosomal antigenic preparations derived from eggs (SEA) or adult worms (SWAP)." | 7.67 | Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis. ( Barsoum, IS; Colley, DG; Dahawi, HS; El Alamy, MA; Gamil, FM; Habib, M, 1984) |
| "The effect of histamine on cell-mediated immune responses of chronic schistosomiasis patients was tested by peripheral blood mononuclear cell (PBMN) reactions to phytohemagglutinin-P (PHA) and soluble schistosomal antigenic preparations derived from eggs (SEA) or adult worms (SWAP)." | 3.67 | Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis. ( Barsoum, IS; Colley, DG; Dahawi, HS; El Alamy, MA; Gamil, FM; Habib, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weinstock, JV | 3 |
| Boros, DL | 3 |
| Barsoum, IS | 1 |
| Dahawi, HS | 1 |
| Gamil, FM | 1 |
| Habib, M | 1 |
| El Alamy, MA | 1 |
| Colley, DG | 1 |
| Chensue, SW | 1 |
| el Hawy, AM | 1 |
| Negm, IA | 1 |
| el-Rakaybe, A | 1 |
| Abdel-Maged, AI | 1 |
| Mansour, RE | 1 |
5 other studies available for cimetidine and Schistosomiasis
| Article | Year |
|---|---|
Alteration of granuloma angiotensin I-converting enzyme activity by regulatory T lymphocytes in murine schistosomiasis.
Topics: Animals; Cimetidine; Cyclophosphamide; Female; Granuloma; Liver; Macrophages; Mice; Mice, Inbred CBA | 1982 |
Immune responses and immunoregulation in relation to human schistosomiasis in Egypt. II. Cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis.
Topics: Adult; Antigens; Cimetidine; Egypt; Female; Histamine; Humans; Immunosuppressive Agents; Larva; Lymp | 1984 |
Modulation of granulomatous hypersensitivity. V. Participation of histamine receptor positive and negative lymphocytes in the granulomatous response of Schistosoma mansoni-infected mice.
Topics: Animals; Cell Migration Inhibition; Cimetidine; Diphenhydramine; Immune Tolerance; Liver; Lymphomato | 1983 |
Heterogeneity of the granulomatous response in the liver, colon, ileum, and ileal Peyer's patches to schistosome eggs in murine schistosomiasis mansoni.
Topics: Animals; Antilymphocyte Serum; Chronic Disease; Cimetidine; Colon; Complement System Proteins; Cyclo | 1981 |
The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.
Topics: Blood Pressure; Cimetidine; Humans; Hypertension, Pulmonary; Nifedipine; Random Allocation; Schistos | 1993 |