cimetidine has been researched along with Schistosomiasis mansoni in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days." | 5.29 | Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994) |
| "Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days." | 1.29 | Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ebeid, FA | 1 |
| Metwally, AA | 1 |
| Botros, SS | 1 |
| Bennet, JL | 1 |
| Kelly, EA | 1 |
| Colley, DG | 1 |
2 other studies available for cimetidine and Schistosomiasis mansoni
| Article | Year |
|---|---|
Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine.
Topics: Animals; Cimetidine; Drug Synergism; Drug Therapy, Combination; Mice; Praziquantel; Schistosomiasis | 1994 |
Effects of immunomanipulations on resistance induced by irradiated Schistosoma mansoni cercarial sensitization of C57BL/6 and CBA/J mice.
Topics: Animals; Cimetidine; Cyclophosphamide; Female; Immunity, Innate; Immunization; Indomethacin; Male; M | 1986 |