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cimetidine and Schistosomiasis mansoni

cimetidine has been researched along with Schistosomiasis mansoni in 2 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Schistosomiasis mansoni: Schistosomiasis caused by Schistosoma mansoni. It is endemic in Africa, the Middle East, South America, and the Caribbean and affects mainly the bowel, spleen, and liver.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days."5.29Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994)
"Cimetidine was tested in doses of 50, 100 and 200 mg/kg for 2 consecutive days; praziquantel was given in doses of 100 and 500 mg/kg for 2 consecutive days."1.29Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine. ( Bennet, JL; Botros, SS; Ebeid, FA; Metwally, AA, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebeid, FA1
Metwally, AA1
Botros, SS1
Bennet, JL1
Kelly, EA1
Colley, DG1

Other Studies

2 other studies available for cimetidine and Schistosomiasis mansoni

ArticleYear
Treatment of experimental schistosomiasis mansoni with praziquantel alone and combined with cimetidine.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:11

    Topics: Animals; Cimetidine; Drug Synergism; Drug Therapy, Combination; Mice; Praziquantel; Schistosomiasis

1994
Effects of immunomanipulations on resistance induced by irradiated Schistosoma mansoni cercarial sensitization of C57BL/6 and CBA/J mice.
    The American journal of tropical medicine and hygiene, 1986, Volume: 35, Issue:4

    Topics: Animals; Cimetidine; Cyclophosphamide; Female; Immunity, Innate; Immunization; Indomethacin; Male; M

1986