cimetidine has been researched along with Sarcoma, Kaposi in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Sarcoma, Kaposi: A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saville, MW | 1 |
| Lietzau, J | 1 |
| Pluda, JM | 1 |
| Feuerstein, I | 1 |
| Odom, J | 1 |
| Wilson, WH | 1 |
| Humphrey, RW | 1 |
| Feigal, E | 1 |
| Steinberg, SM | 1 |
| Broder, S | 1 |
| Smith, TJ | 1 |
| Kaplowitz, LG | 1 |
| Calvieri, S | 1 |
| Fattorossi, A | 1 |
2 trials available for cimetidine and Sarcoma, Kaposi
| Article | Year |
|---|---|
Treatment of HIV-associated Kaposi's sarcoma with paclitaxel.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cimetidine; Dexamethasone; Diphenhydramine; Drug Therapy, | 1995 |
Pilot study of cimetidine in the treatment of Kaposi's sarcoma in patients with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Cimetidine; Humans; Male; Pilot Projects; Sarcoma, Kaposi | 1991 |
1 other study available for cimetidine and Sarcoma, Kaposi
| Article | Year |
|---|---|
Cimetidine for Kaposi's sarcoma.
Topics: Aged; Cimetidine; Humans; Male; Sarcoma, Kaposi | 1985 |