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cimetidine and Respiratory Distress Syndrome

cimetidine has been researched along with Respiratory Distress Syndrome in 6 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Respiratory Distress Syndrome: A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Porcine Pseudomonas adult respiratory distress syndrome (ARDS) has been shown to respond to combination therapy of 150 mg of cimetidine, 12."3.67Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model. ( Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bone, RC1
Martin, LF1
Booth, FV1
Reines, HD1
Deysach, LG1
Kochman, RL1
Erhardt, LJ1
Geis, GS1
Byrne, K2
Sielaff, TD4
Michna, B1
Carey, PD2
Blocher, CR4
Vasquez, A2
Sugerman, HJ4
Tatum, JL3
Hirsh, JI1
Kellum, JM1

Trials

1 trial available for cimetidine and Respiratory Distress Syndrome

ArticleYear
Stress ulcers and organ failure in intubated patients in surgical intensive care units.
    Annals of surgery, 1992, Volume: 215, Issue:4

    Topics: Cause of Death; Cimetidine; Critical Care; Double-Blind Method; Female; Follow-Up Studies; Gastrosco

1992

Other Studies

5 other studies available for cimetidine and Respiratory Distress Syndrome

ArticleYear
Treatment of severe hypoxemia due to the adult respiratory distress syndrome.
    Archives of internal medicine, 1980, Volume: 140, Issue:1

    Topics: Cimetidine; Humans; Hypoxia; Monitoring, Physiologic; Oxygen; Positive-Pressure Respiration; Pressur

1980
Increased survival time after delayed histamine and prostaglandin blockade in a porcine model of severe sepsis-induced lung injury.
    Critical care medicine, 1990, Volume: 18, Issue:3

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Extravascular Lung Water; Hemodynam

1990
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS.
    Circulatory shock, 1990, Volume: 30, Issue:2

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomona

1990
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model.
    Surgery, 1987, Volume: 102, Issue:2

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin

1987
Treatment of porcine Pseudomonas ARDS with combination drug therapy.
    The Journal of trauma, 1987, Volume: 27, Issue:12

    Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug C

1987