cimetidine has been researched along with Renal Insufficiency, Chronic in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is a potent organic cation transporter 2/multidrug and toxin extrusion protein inhibitor." | 1.56 | A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals. ( Ebner, T; Hanke, N; Ishiguro, N; Lehr, T; Müller, F; Nock, V; Selzer, D; Stopfer, P; Türk, D; Wiebe, S, 2020) |
| " The aim of this study was to assess whether appropriate dosage adjustments were made in hospitalized patients with renal impairment." | 1.42 | Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. ( Getachew, H; Shibeshi, W; Tadesse, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hanke, N | 1 |
| Türk, D | 1 |
| Selzer, D | 1 |
| Ishiguro, N | 1 |
| Ebner, T | 1 |
| Wiebe, S | 1 |
| Müller, F | 1 |
| Stopfer, P | 1 |
| Nock, V | 1 |
| Lehr, T | 1 |
| Getachew, H | 1 |
| Tadesse, Y | 1 |
| Shibeshi, W | 1 |
| Musso, CG | 1 |
| Michelángelo, H | 1 |
| Vilas, M | 1 |
| Martinez, B | 1 |
| Bonetto, A | 1 |
| Jauregui, R | 1 |
| Algranati, L | 1 |
3 other studies available for cimetidine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals.
Topics: Adult; Cimetidine; Drug Interactions; Humans; Hypoglycemic Agents; Metformin; Pharmacogenetics; Rena | 2020 |
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents | 2015 |
Renal creatinine handling in very old patients with chronic renal disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cimetidine; Creatinine; Female; Glomerular Filtration R | 2011 |