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cimetidine and Prostatic Neoplasms

cimetidine has been researched along with Prostatic Neoplasms in 6 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine has been hypothesized to exert a cancer preventive effect on the prostate due to its ability to inhibit the binding of dihydrotestosterone to androgen receptors."5.31Cimetidine use and risk of prostate and breast cancer. ( Cushing-Haugen, KL; Rossing, MA; Scholes, D; Voigt, LF, 2000)
"Men were followed up for subsequent prostate cancer by linkage to the Surveillance, Epidemiology and End Results cancer registry."1.33Cimetidine use and the risk for prostate cancer: results from the VITAL cohort study. ( Dublin, S; Velicer, CM; White, E, 2006)
"Cimetidine has been hypothesized to exert a cancer preventive effect on the prostate due to its ability to inhibit the binding of dihydrotestosterone to androgen receptors."1.31Cimetidine use and risk of prostate and breast cancer. ( Cushing-Haugen, KL; Rossing, MA; Scholes, D; Voigt, LF, 2000)
"All patients had bone metastases."1.28Treatment of hormone-refractory stage D carcinoma of prostate with coumarin (1,2-benzopyrone) and cimetidine: a pilot study. ( Butler, K; Hermansen, D; Marshall, ME, 1990)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Velicer, CM1
Dublin, S1
White, E1
Rossing, MA1
Scholes, D1
Cushing-Haugen, KL1
Voigt, LF1
Møller, H1
Mellemgaard, A1
Stolinsky, DC1
Marshall, ME1
Butler, K1
Hermansen, D1
Lahat, N1
Alexander, B1
Levin, DR1
Moskovitz, B1

Other Studies

6 other studies available for cimetidine and Prostatic Neoplasms

ArticleYear
Cimetidine use and the risk for prostate cancer: results from the VITAL cohort study.
    Annals of epidemiology, 2006, Volume: 16, Issue:12

    Topics: Aged; Cimetidine; Cohort Studies; Histamine H2 Antagonists; Humans; Male; Middle Aged; Proportional

2006
Cimetidine use and risk of prostate and breast cancer.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Case-Control Studies; Cimetidine; Female; Histamin

2000
Prostate cancer incidence in cimetidine users.
    Journal of the National Cancer Institute, 1992, Mar-04, Volume: 84, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Humans; Incidence; Male; Middle Aged; Prostatic Neoplasm

1992
Prostate cancer and histamine2 antagonists.
    Journal of the National Cancer Institute, 1991, Nov-06, Volume: 83, Issue:21

    Topics: Cimetidine; Histamine Antagonists; Humans; Male; Prostatic Neoplasms

1991
Treatment of hormone-refractory stage D carcinoma of prostate with coumarin (1,2-benzopyrone) and cimetidine: a pilot study.
    The Prostate, 1990, Volume: 17, Issue:2

    Topics: Aged; Bone Neoplasms; Cimetidine; Coumarins; Drug Therapy, Combination; Humans; Male; Middle Aged; N

1990
The relationship between clinical stage, natural killer activity and related immunological parameters in adenocarcinoma of the prostate.
    Cancer immunology, immunotherapy : CII, 1989, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Aged; Cimetidine; Cytotoxicity, Immunologic; Humans; Indomethacin; Interleukin-2; Ki

1989