cimetidine has been researched along with Prostatic Hyperplasia in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine was found to be no more active than vitamin C in treating benign prostatic hypertrophy." | 2.67 | Controlled study of cimetidine in the treatment of benign prostatic hypertrophy. ( Brooks, ME; Lindner, A; Ramon, J, 1990) |
| "Cimetidine is a H-2-receptor histamine antagonist, cannitracin is an antifungal antibiotic derived from Strp-griseus and tolazoline is an alpha-adrenergic blocker similar to phentolamine." | 1.27 | Effects of cimetidine, progesterone, cannitracin and tolazoline on the weight and DNA content of the testosterone-induced hyperplastic prostate of the rat. ( Chen, DY; Chen, W; Kang, JS; Zhou, XM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, M | 1 |
| Lindner, A | 1 |
| Ramon, J | 1 |
| Brooks, ME | 1 |
| Chen, W | 1 |
| Zhou, XM | 1 |
| Chen, DY | 1 |
| Kang, JS | 1 |
1 trial available for cimetidine and Prostatic Hyperplasia
| Article | Year |
|---|---|
Controlled study of cimetidine in the treatment of benign prostatic hypertrophy.
Topics: Adult; Aged; Cimetidine; Double-Blind Method; Humans; Male; Middle Aged; Prostatic Hyperplasia; Rand | 1990 |
2 other studies available for cimetidine and Prostatic Hyperplasia
| Article | Year |
|---|---|
Cimetidine for hypertrophic prostate?
Topics: Cimetidine; Guanidines; Humans; Male; Prostatic Hyperplasia | 1979 |
Effects of cimetidine, progesterone, cannitracin and tolazoline on the weight and DNA content of the testosterone-induced hyperplastic prostate of the rat.
Topics: Androgen Antagonists; Animals; Anti-Bacterial Agents; Antifungal Agents; Cimetidine; DNA; Drug Evalu | 1988 |