cimetidine has been researched along with Porphyrias in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 43-yr-old man with abdominal fullness was treated with oral cimetidine during remission of acute intermittent porphyria." | 7.67 | Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report. ( Hirayama, C; Horie, Y; Udagawa, M, 1987) |
| "A 43-yr-old man with abdominal fullness was treated with oral cimetidine during remission of acute intermittent porphyria." | 3.67 | Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report. ( Hirayama, C; Horie, Y; Udagawa, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horie, Y | 3 |
| Okano, J | 1 |
| Kitaoka, S | 1 |
| Tajima, F | 2 |
| Kawasaki, H | 2 |
| Norimoto, M | 1 |
| Sasaki, H | 2 |
| Nanba, E | 1 |
| Gullotti, D | 1 |
| Schillaci, L | 1 |
| Amato, S | 1 |
| Salerno, L | 1 |
| Brouard, A | 1 |
| Conort, O | 1 |
| Terrier, JL | 1 |
| Marcus, DL | 1 |
| Nadel, H | 1 |
| Lew, G | 1 |
| Freedman, ML | 1 |
| Baccino, E | 1 |
| Lan Cheong Wah, LS | 1 |
| Bressollette, L | 1 |
| Mottier, D | 1 |
| Udagawa, M | 1 |
| Hirayama, C | 1 |
| Singh, R | 1 |
| Agarwal, N | 1 |
1 review available for cimetidine and Porphyrias
| Article | Year |
|---|---|
[Treatment of the porphyrias].
Topics: beta Carotene; Bloodletting; Carotenoids; Cimetidine; Female; Glucose; Hemin; Humans; Interferons; L | 1995 |
8 other studies available for cimetidine and Porphyrias
| Article | Year |
|---|---|
Clinical usefulness of cimetidine treatment for acute relapse in intermittent porphyria.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Glucose; Cimetidine; Coproporphyrins; Feces; Humans | 1995 |
[Clinical and laboratory findings concerning at first dietary and afterwards cimetidine treatment of acute intermittent porphyria].
Topics: Acute Disease; Adult; Aminolevulinic Acid; Cimetidine; Coproporphyrins; Female; Humans; Middle Aged; | 1994 |
A new approach for the treatment of acute porphyria.
Topics: Cimetidine; Dietary Supplements; Glucose; Hemin; Histamine H2 Antagonists; Humans; Porphyrias | 1999 |
H2-receptor antagonists and acute intermittent porphyria.
Topics: Acute Disease; Cimetidine; Drug Evaluation; Famotidine; Humans; Porphyrias; Ranitidine; Skin Disease | 1991 |
Cimetidine suppresses chemically induced experimental hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chemical and Drug Induced Liver Inju | 1990 |
Cimetidine in the treatment of acute intermittent porphyria.
Topics: Acute Disease; Adult; Cimetidine; Female; Humans; Liver Diseases; Porphyrias | 1989 |
Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Cimetidine; Humans; Liver D | 1987 |
Can cimetidine induce porphyria?
Topics: Acute Disease; Adult; Cimetidine; Female; Humans; Porphyrias | 1985 |