cimetidine has been researched along with Porphyria, Acute Intermittent in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The optimal dosage and duration of treatment with cimetidine have not been established and are likely to be patient-specific." | 2.40 | Cimetidine in the treatment of acute intermittent porphyria. ( Rogers, PD, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Igarashi, M | 1 |
| Daimon, M | 1 |
| Usuki, K | 1 |
| Hirai, Y | 1 |
| Nakahara, F | 1 |
| Iijima, K | 1 |
| Iki, S | 1 |
| Kondo, M | 1 |
| Kato, T | 1 |
| Urabe, A | 1 |
| Cherem, JH | 1 |
| Malagon, J | 1 |
| Nellen, H | 1 |
| Nakajima, A | 1 |
| Mishina, M | 1 |
| Nagashima, M | 1 |
| Ujiie, T | 1 |
| Hara, K | 1 |
| Terashi, A | 1 |
| Siepmann, M | 1 |
| Stölzel, U | 1 |
| Sieg, I | 1 |
| Leo-Rossberg, I | 1 |
| Riecken, EO | 1 |
| Doss, MO | 1 |
| Rogers, PD | 1 |
1 review available for cimetidine and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Cimetidine in the treatment of acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Animals; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Hemin; Humans | 1997 |
4 other studies available for cimetidine and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
[A family of acute intermittent porphyria].
Topics: Abdominal Pain; Biomarkers; Cimetidine; Exons; Genetic Carrier Screening; Glucose; Humans; Hydroxyme | 2004 |
Cimetidine and acute intermittent porphyria.
Topics: 5-Aminolevulinate Synthetase; Adult; Cimetidine; Female; Heme; Humans; Porphyria, Acute Intermittent | 2005 |
[A case of acute intermittent porphyria treated with cimetidine].
Topics: Adult; Cimetidine; Female; Humans; Porphyria, Acute Intermittent | 1993 |
[Cimetidine in treatment of acute intermittent porphyria].
Topics: Administration, Oral; Adult; Cimetidine; Drug Administration Schedule; Female; Follow-Up Studies; Hu | 1993 |