cimetidine has been researched along with Polycythemia Vera in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-four patients with polycythemia vera complicated by pruritus were treated with 900 mg of cimetidine daily for 30 days and their responses to treatment were evaluated." | 7.66 | The use of cimetidine for the treatment of pruritus in polycythemia vera. ( Cooperberg, AA; Donovan, PB; Dresch, C; Goldberg, JD; Najean, Y; Pisciotta, AV; Weick, JK, 1982) |
| "Thirty-four patients with polycythemia vera complicated by pruritus were treated with 900 mg of cimetidine daily for 30 days and their responses to treatment were evaluated." | 3.66 | The use of cimetidine for the treatment of pruritus in polycythemia vera. ( Cooperberg, AA; Donovan, PB; Dresch, C; Goldberg, JD; Najean, Y; Pisciotta, AV; Weick, JK, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weick, JK | 1 |
| Donovan, PB | 1 |
| Najean, Y | 1 |
| Dresch, C | 1 |
| Pisciotta, AV | 1 |
| Cooperberg, AA | 1 |
| Goldberg, JD | 1 |
| Aubert, M | 1 |
| Quilicchini, R | 1 |
| Carcassonne, Y | 1 |
| Easton, P | 1 |
| Galbraith, PR | 1 |
| Scott, GL | 1 |
| Horton, RJ | 1 |
4 other studies available for cimetidine and Polycythemia Vera
| Article | Year |
|---|---|
The use of cimetidine for the treatment of pruritus in polycythemia vera.
Topics: Cimetidine; Guanidines; Humans; Polycythemia Vera; Pruritus | 1982 |
[Trial treatment of the pruritus in Vaquez' disease with cimetidine].
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Polycythemia Vera; Pruritus | 1980 |
Cimetidine treatment of pruritus in polycythemia vera.
Topics: Cimetidine; Female; Guanidines; Humans; Middle Aged; Polycythemia Vera; Pruritus | 1978 |
Pruritus, cimetidine and polycythemia.
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Polycythemia Vera; Pruritus | 1979 |