cimetidine has been researched along with Pneumonia in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Pneumonia: Infection of the lung often accompanied by inflammation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-six patients were randomized to receive cimetidine and their rate of pneumonia was 12." | 9.07 | Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate. ( Celoria, G; Dawson, J; Navab, F; Ryan, P; Teres, D, 1993) |
| " infusion of cimetidine, a histamine-2 (H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage when compared with placebo and if that usage is associated with an increased risk of nosocomial pneumonia." | 9.07 | Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. ( Booth, FV; Bowman, SC; D'Ambrosio, CA; Hampsey, J; Jacobs, DM; Karlstadt, RG; Martin, LF; Rockhold, FW; Silverstein, JH, 1993) |
| "The observed effects of cimetidine and sucralfate on the incidence and severity of hemorrhage from stress-related gastritis were not significant when compared with no treatment." | 5.07 | Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. A randomized, controlled, single-blind study. ( Ben-Menachem, T; Bresalier, RS; Divine, G; Fogel, R; Hadzijahic, N; Patel, RV; Touchette, M; Verter, J; Zarowitz, BJ, 1994) |
| "We have compared the effectiveness of non-acid neutralizing stress ulcer prophylaxis (SUC) with sucralfate (n = 48) with that of acid neutralizing prophylaxis (AN) utilizing antacids and cimetidine (n = 48) in the prevention of stress ulcer bleeding and nosocomial pneumonia (PN) in thermally injured patients." | 5.07 | Comparison of acid neutralizing and non-acid neutralizing stress ulcer prophylaxis in thermally injured patients. ( Cioffi, WG; Mason, AD; McManus, AT; McManus, WF; Pruitt, BA; Rue, LW, 1994) |
| "Fifty-six patients were randomized to receive cimetidine and their rate of pneumonia was 12." | 5.07 | Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate. ( Celoria, G; Dawson, J; Navab, F; Ryan, P; Teres, D, 1993) |
| " infusion of cimetidine, a histamine-2 (H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage when compared with placebo and if that usage is associated with an increased risk of nosocomial pneumonia." | 5.07 | Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. ( Booth, FV; Bowman, SC; D'Ambrosio, CA; Hampsey, J; Jacobs, DM; Karlstadt, RG; Martin, LF; Rockhold, FW; Silverstein, JH, 1993) |
| "Critically ill trauma patients were entered in a prospective, randomized trial to determine the role of gastric colonization in the development of pneumonia." | 2.67 | Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial. ( Burchard, KW; DeMaria, E; McDonald, L; Peterson, D; Robinson, A; Simms, HH, 1991) |
| "Diarrhea is the most common complication and occurs more frequently in patients who receive antacids." | 1.28 | Nonhemorrhagic gastrointestinal complications in acute respiratory failure. ( Dark, DS; Pingleton, SK, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawes, P | 1 |
| Atherton, ST | 1 |
| Shapiro, GG | 1 |
| Christie, DL | 1 |
| Ben-Menachem, T | 2 |
| Fogel, R | 2 |
| Patel, RV | 2 |
| Touchette, M | 1 |
| Zarowitz, BJ | 2 |
| Hadzijahic, N | 1 |
| Divine, G | 1 |
| Verter, J | 1 |
| Bresalier, RS | 2 |
| Kondratenko, TY | 1 |
| Zacharova, IV | 1 |
| Kuzina, NV | 1 |
| Severin, ES | 1 |
| Kornilova, ZCh | 1 |
| Perelman, MI | 1 |
| Cioffi, WG | 1 |
| McManus, AT | 1 |
| Rue, LW | 1 |
| Mason, AD | 1 |
| McManus, WF | 1 |
| Pruitt, BA | 1 |
| Ryan, P | 1 |
| Dawson, J | 1 |
| Teres, D | 1 |
| Celoria, G | 1 |
| Navab, F | 1 |
| Tryba, M | 2 |
| Martin, LF | 2 |
| Booth, FV | 2 |
| Karlstadt, RG | 2 |
| Silverstein, JH | 1 |
| Jacobs, DM | 1 |
| Hampsey, J | 1 |
| Bowman, SC | 1 |
| D'Ambrosio, CA | 1 |
| Rockhold, FW | 1 |
| Fabian, TC | 1 |
| Boucher, BA | 1 |
| Croce, MA | 1 |
| Kuhl, DA | 1 |
| Janning, SW | 1 |
| Coffey, BC | 1 |
| Kudsk, KA | 1 |
| McCarthy, BD | 1 |
| Schiffman, RM | 1 |
| Nerenz, DR | 1 |
| Wood, CA | 1 |
| Isaacson, MI | 1 |
| Hibbs, MS | 1 |
| Reines, HD | 1 |
| Deysach, LG | 1 |
| Kochman, RL | 1 |
| Erhardt, LJ | 1 |
| Geis, GS | 1 |
| Simms, HH | 1 |
| DeMaria, E | 1 |
| McDonald, L | 1 |
| Peterson, D | 1 |
| Robinson, A | 1 |
| Burchard, KW | 1 |
| Karlstadt, R | 1 |
| Palmer, RH | 2 |
| Dark, DS | 1 |
| Pingleton, SK | 1 |
| Parr, NJ | 1 |
| Craven, DE | 1 |
| Kunches, LM | 1 |
| Kilinsky, V | 1 |
| Lichtenberg, DA | 1 |
| Make, BJ | 1 |
| McCabe, WR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Lactobacillus GG in the Prophylaxis of Ventilator Associated Pneumonia: A Prospective, Randomized, Placebo-controlled, Double-blind Study[NCT00613795] | Phase 3 | 125 participants (Anticipated) | Interventional | 2004-08-31 | Completed | ||
| Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit[NCT00633035] | Phase 4 | 60 participants (Actual) | Interventional | 2007-09-30 | Completed | ||
| Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer Prophylaxis in Patients After Major Abdominal Surgery[NCT00839488] | Phase 4 | 6 participants (Actual) | Interventional | 2008-04-30 | Terminated (stopped due to the chief of GS left the hopsital and the successor did't want to keep on this study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cimetidine and Pneumonia
| Article | Year |
|---|---|
Gastroesophageal reflux and asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bethanechol; Bethanechol Compounds; Child; Child, Preschool; Cimeti | 1983 |
Prophylaxis for stress-related gastrointestinal hemorrhage: a cost effectiveness analysis.
Topics: Anti-Ulcer Agents; Cimetidine; Cost-Benefit Analysis; Cross Infection; Decision Trees; Drug Costs; G | 1996 |
[Acid reducing drugs for prevention of stress ulcer: cause for the development of nosocomial pneumonia? Arguments pro].
Topics: Anti-Ulcer Agents; Cimetidine; Colony Count, Microbial; Critical Care; Cross Infection; Gastric Acid | 1991 |
7 trials available for cimetidine and Pneumonia
| Article | Year |
|---|---|
Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. A randomized, controlled, single-blind study.
Topics: Adult; Aged; Blood Transfusion; Cimetidine; Critical Illness; Cross Infection; Female; Gastritis; Ga | 1994 |
Comparison of acid neutralizing and non-acid neutralizing stress ulcer prophylaxis in thermally injured patients.
Topics: Adult; Antacids; Burns; Cimetidine; Drug Therapy, Combination; Humans; Peptic Ulcer; Pneumonia; Stre | 1994 |
Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Cross Infection; Femal | 1993 |
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind | 1993 |
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind | 1993 |
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind | 1993 |
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind | 1993 |
Pneumonia and stress ulceration in severely injured patients. A prospective evaluation of the effects of stress ulcer prophylaxis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cimetidine; Female; Humans; Infusions, Intravenous; I | 1993 |
Pneumonia and stress ulceration in severely injured patients. A prospective evaluation of the effects of stress ulcer prophylaxis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cimetidine; Female; Humans; Infusions, Intravenous; I | 1993 |
Pneumonia and stress ulceration in severely injured patients. A prospective evaluation of the effects of stress ulcer prophylaxis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cimetidine; Female; Humans; Infusions, Intravenous; I | 1993 |
Pneumonia and stress ulceration in severely injured patients. A prospective evaluation of the effects of stress ulcer prophylaxis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Cimetidine; Female; Humans; Infusions, Intravenous; I | 1993 |
Stress ulcers and organ failure in intubated patients in surgical intensive care units.
Topics: Cause of Death; Cimetidine; Critical Care; Double-Blind Method; Female; Follow-Up Studies; Gastrosco | 1992 |
Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial.
Topics: Adolescent; Adult; Antacids; Bacteria; Cimetidine; Cross Infection; Gastric Juice; Humans; Hydrogen- | 1991 |
9 other studies available for cimetidine and Pneumonia
| Article | Year |
|---|---|
Cimetidine in the critically ill: a cautionary note.
Topics: Bacteria; Cimetidine; Critical Care; Guanidines; Humans; Pneumonia; Stomach | 1980 |
The study of histamine H1- and H2-receptors in human lung cancer.
Topics: Adenocarcinoma; Adult; Airway Obstruction; Chronic Disease; Cimetidine; Humans; Lung Neoplasms; Midd | 1993 |
Pneumonia due to stress ulcer prophylaxis with cimetidine: a necessary consequence?
Topics: Cimetidine; Humans; Intubation, Gastrointestinal; Pneumonia; Stomach Ulcer; Stress, Physiological | 1993 |
Cimetidine and mental confusion.
Topics: Cimetidine; Cognition Disorders; Female; Guanidines; Humans; Middle Aged; Pneumonia | 1978 |
Gastric pH control and pneumonia in the critically ill.
Topics: Cimetidine; Humans; Pneumonia; Research Design | 1990 |
The effect of H2 receptor antagonists on intragastric pH in critically ill patients.
Topics: Cimetidine; Critical Care; Cross Infection; Gastric Acid; Gastric Acidity Determination; Humans; Hyd | 1989 |
Nonhemorrhagic gastrointestinal complications in acute respiratory failure.
Topics: Acute Disease; Antacids; Cimetidine; Diarrhea; Female; Gastrointestinal Diseases; Humans; Intensive | 1989 |
Cimetidine and gastrointestinal haemorrhage in critically ill patients.
Topics: Cimetidine; Gastrointestinal Hemorrhage; Humans; Pneumonia | 1986 |
Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation.
Topics: Adult; Aged; Cimetidine; Cross Infection; Female; Humans; Male; Massachusetts; Middle Aged; Monitori | 1986 |