Page last updated: 2024-10-25

cimetidine and Pituitary Neoplasms

cimetidine has been researched along with Pituitary Neoplasms in 10 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine, which strongly stimulates prolactin release in healthy man, was unable to modify prolactin levels in prolactin-secreting pituitary adenomas."3.66Failure of drugs acting on H2-receptors to modify plasma prolactin levels in pituitary adenomas: evidence for a suprapituitary locus of action. ( Bertaccini, G; Ceda, GP; Scarpignato, C; Valenti, G, 1981)
"Baclofen was unable to significantly rise serum PRL levels in healthy subjects and in patients affected by prolactinoma and furthermore did not interfere with PRL rise domperidone induced."1.27[Prolactin after baclofen in healthy subjects and prolactinoma patients]. ( Carletti, P; Ferretti, GF; Marchesi, GF; Morosini, PP; Nardi, B; Sarzani, R, 1985)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geokas, MC1
Yalow, RS1
Straus, EW1
Gold, EM1
Bacchi Modena, A1
Vadora, E1
Fiaschetti, D1
Micucci, G1
Lombardozzi, L1
Carlson, HE1
Chang, RJ1
Meyer, NV1
Lu, KH1
Judd, HL1
Iodice, M1
Lombardi, G1
Tommaselli, A1
Rossi, R1
Annunziato, L1
Minozzi, M1
Gasparoni, P1
Rota, G1
Fioretti, D1
Lo Giudice, C1
Manente, P1
Valmachino, G1
Conte, N1
Scarpignato, C1
Valenti, G1
Ceda, GP1
Bertaccini, G1
Gonzalez-Villapando, C1
Szabo, M1
Frohman, LA1
Luttwak, EM1
Saltz, NJ1
Morosini, PP1
Carletti, P1
Sarzani, R1
Ferretti, GF1
Marchesi, GF1
Nardi, B1
Kikuchi, Y1
Seki, K1
Momose, E1
Kizawa, I1
Oomori, K1
Shima, K1
Mukai, K1
Kato, K1

Other Studies

10 other studies available for cimetidine and Pituitary Neoplasms

ArticleYear
Peptide radioimmunoassays in clinical medicine.
    Annals of internal medicine, 1982, Volume: 97, Issue:3

    Topics: Acid Phosphatase; Amylases; Animals; Cimetidine; Creatine Kinase; Dogs; Female; Gastrins; Hexosamini

1982
[Role of H2 receptors in controlling prolactin release. Decreased response to cimetidine in patients with prolactin-secreting adenoma and idiopathic hyperprolactinemia].
    Minerva ginecologica, 1984, Volume: 36, Issue:6

    Topics: Adenoma; Adult; Cimetidine; Female; Galactorrhea; Humans; Pituitary Neoplasms; Pregnancy; Prolactin;

1984
Effect of cimetidine on serum prolactin in normal women and patients with hyperprolactinaemia.
    Clinical endocrinology, 1981, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Pituitary Neoplasms; P

1981
Agreement of prolactin response to cimetidine and nomifensine in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
    Neuroendocrinology, 1982, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Cimetidine; Female; Guanidines; Humans; Isoquinolines; Male; Nomifensine; Pituita

1982
[Cimetidine and primary hyperparathyroidism: failure of reduction of blood levels of parathyroid hormone in 5 cases of primary hyperparathyroidism].
    La Clinica terapeutica, 1981, Jul-15, Volume: 98, Issue:1

    Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism; Male; Middle Aged; Parathyroid H

1981
Failure of drugs acting on H2-receptors to modify plasma prolactin levels in pituitary adenomas: evidence for a suprapituitary locus of action.
    International pharmacopsychiatry, 1981, Volume: 16, Issue:2

    Topics: Adenoma; Cimetidine; Female; Guanidines; Humans; Hypothalamus; Methylhistamines; Pituitary Neoplasms

1981
Central nervous system-mediated stimulation of prolactin secretion by cimetidine, a histamine H2-receptor antagonist: impaired responsiveness in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: Adenoma; Adolescent; Adult; Animals; Carbidopa; Cimetidine; Female; Guanidines; Humans; Levodopa; Ma

1980
The progressive Zollinger-Ellison syndrome in multiple endocrine neoplasia.
    Surgery, gynecology & obstetrics, 1988, Volume: 167, Issue:5

    Topics: Adult; Apudoma; Cimetidine; Follow-Up Studies; Gastrectomy; Gastrinoma; Humans; Male; Middle Aged; M

1988
[Prolactin after baclofen in healthy subjects and prolactinoma patients].
    Bollettino della Societa italiana di biologia sperimentale, 1985, Jan-30, Volume: 61, Issue:1

    Topics: Adult; Baclofen; Cimetidine; Domperidone; Dopamine; Drug Interactions; Female; Humans; Hypothalamo-H

1985
Establishment and characterization of a new human cultured cell line from a prolactin-secreting pituitary adenoma.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 2

    Topics: Adenoma; Bromocriptine; Cell Division; Cell Line; Cimetidine; Estradiol; Humans; Pituitary Neoplasms

1985