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cimetidine and Persistent Fetal Circulation Syndrome

cimetidine has been researched along with Persistent Fetal Circulation Syndrome in 2 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Persistent Fetal Circulation Syndrome: A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by severe pulmonary vasoconstriction (reactive type), hypertrophy of pulmonary arterial muscle (hypertrophic type), or abnormally developed pulmonary arterioles (hypoplastic type). The newborn patient exhibits CYANOSIS and ACIDOSIS due to the persistence of fetal circulatory pattern of right-to-left shunting of blood through a patent ductus arteriosus (DUCTUS ARTERIOSUS, PATENT) and at times a patent foramen ovale (FORAMEN OVALE, PATENT).

Research Excerpts

ExcerptRelevanceReference
"A newborn was treated with tolazoline for persistent pulmonary hypertension."3.68[Interaction of tolazoline and cimetidine in persistent fetal circulation of the newborn infant]. ( Hanssler, L; Roll, C, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roll, C1
Hanssler, L1
Huang, CB1
Huang, SC1

Other Studies

2 other studies available for cimetidine and Persistent Fetal Circulation Syndrome

ArticleYear
[Interaction of tolazoline and cimetidine in persistent fetal circulation of the newborn infant].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1993, Volume: 141, Issue:4

    Topics: Blood Pressure; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Humans;

1993
Caution with use of cimetidine in tolazoline induced upper gastrointestinal bleeding.
    Changgeng yi xue za zhi, 1996, Volume: 19, Issue:3

    Topics: Cimetidine; Drug Interactions; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Infant

1996