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cimetidine and Parathyroid Neoplasms

cimetidine has been researched along with Parathyroid Neoplasms in 10 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Parathyroid Neoplasms: Tumors or cancer of the PARATHYROID GLANDS.

Research Excerpts

ExcerptRelevanceReference
"Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable."7.67The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987)
"In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally."7.66Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980)
"We studied in vitro the presence of histamine and the effect of histamine and its antagonists on cAMP accumulation in parathyroid tissue (parathyroid adenoma or hyperplasia) from patients with primary hyperparathyroidism."7.66Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro. ( Abbound, HE; Dousa, TP; Edis, AJ; Heath, H; Zimmerman, D, 1981)
"Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism."5.27The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983)
"The effect of cimetidine on basal and histamine-induced PTH secretion was tested using single cell suspensions obtained from (a) primary parathyroid adenomas, and (b) secondary hyperplastic parathyroid tissue from patients undergoing chronic hemodialysis."3.67Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro. ( Beyer, J; Krause, U; Rothmund, M; Schärfe, T; Wagner, PK, 1984)
"Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable."3.67The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987)
"In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally."3.66Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980)
"We studied in vitro the presence of histamine and the effect of histamine and its antagonists on cAMP accumulation in parathyroid tissue (parathyroid adenoma or hyperplasia) from patients with primary hyperparathyroidism."3.66Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro. ( Abbound, HE; Dousa, TP; Edis, AJ; Heath, H; Zimmerman, D, 1981)
"Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism."1.27The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sherwood, JK2
Ackroyd, FW2
Garcia, M2
Friesen, SR1
Hermreck, AS1
Brackett, CE1
Schimke, RN1
Abbound, HE1
Zimmerman, D1
Edis, AJ1
Heath, H1
Dousa, TP1
Brennan, MF1
Willis, IH1
Minervini, D1
Seiden, EF1
Wagner, PK1
Krause, U1
Schärfe, T1
Beyer, J1
Rothmund, M1
Klein, I1
Lehotay, DC1
Watson, CG1
Rogerson, B1
Levey, GS1
Gasparoni, P1
Rota, G1
Fioretti, D1
Lo Giudice, C1
Manente, P1
Valmachino, G1
Conte, N1
Sasaki, H1
Miyake, K1
Okumura, M1
Eimoto, T1
Sotsiou, FC1
Singhellakis, PN1
Nikou, AD1
Pappas, AD1
Vambouka, C1
Sklivagou, NG1
Ikkos, DG1

Reviews

1 review available for cimetidine and Parathyroid Neoplasms

ArticleYear
Primary hyperparathyroidism.
    Advances in surgery, 1983, Volume: 16

    Topics: Adenoma; Aged; Cimetidine; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Male;

1983

Other Studies

9 other studies available for cimetidine and Parathyroid Neoplasms

ArticleYear
Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism.
    Lancet (London, England), 1980, Mar-22, Volume: 1, Issue:8169

    Topics: Adenoma; Administration, Oral; Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperpar

1980
Case reports; Cimetidine in the management of synchronous crises of MEA I.
    World journal of surgery, 1980, Volume: 4, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Cimetidine; Female; Guanidines; Humans; Multiple Endocrine Neoplasia

1980
Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:2

    Topics: Adenoma; Cimetidine; Cyclic AMP; Female; Histamine; Humans; In Vitro Techniques; Isoproterenol; Male

1981
The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation.
    Surgery, gynecology & obstetrics, 1983, Volume: 157, Issue:6

    Topics: Adenoma; Calcium; Cimetidine; Humans; Hypocalcemia; Parathyroid Glands; Parathyroid Hormone; Parathy

1983
Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro.
    Nephron, 1984, Volume: 36, Issue:2

    Topics: Adenoma; Cimetidine; Dose-Response Relationship, Drug; Histamine; Humans; Hyperparathyroidism; Hyper

1984
Human parathyroid adenoma adenylate cyclase: stimulation by histamine that is blocked by cimetidine.
    Metabolism: clinical and experimental, 1981, Volume: 30, Issue:7

    Topics: Adenoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cimetidine; Dose-Response Relationship, Dru

1981
[Cimetidine and primary hyperparathyroidism: failure of reduction of blood levels of parathyroid hormone in 5 cases of primary hyperparathyroidism].
    La Clinica terapeutica, 1981, Jul-15, Volume: 98, Issue:1

    Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism; Male; Middle Aged; Parathyroid H

1981
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1988, Volume: 77, Issue:1

    Topics: Adenoma; Aged; Alkaline Phosphatase; Cimetidine; Etidronic Acid; Humans; Hypercalcemia; Hyperparathy

1988
The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism.
    The Journal of pathology, 1987, Volume: 151, Issue:4

    Topics: Adenoma; Adolescent; Adult; Aged; Calcium; Cimetidine; Female; Humans; Hyperparathyroidism; Hyperpla

1987