cimetidine has been researched along with Pancytopenia in 8 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987." | 7.68 | [Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990) |
| "We describe a 26 year-old male with a pancytopenia possibly due to cimetidine." | 7.68 | Cimetidine induced pancytopenia. Effect on human CFU-MIX colony formation. ( De Bock, R; Korthout, M; Peetermans, ME; Uyttenbroeck, W; Van Bockstaele, DR, 1990) |
| "When cimetidine was stopped, bone marrow recovered, and myalgia and encephalopathy subsided." | 5.27 | Immune basis for cimetidine-induced pancytopenia. ( Enat, R; Katz, R; Nagler, A; Pollack, S; Rozenbaum, H; Tatarsky, I, 1987) |
| "A 72-year-old woman had been given cimetidine 400mg/day for her gastritis since June 17, 1987." | 3.68 | [Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction]. ( Itoh, T; Miyanishi, E; Morita, K; Nakase, K; Shirakawa, S; Tsuji, K, 1990) |
| "When cimetidine was stopped, bone marrow recovered, and myalgia and encephalopathy subsided." | 1.27 | Immune basis for cimetidine-induced pancytopenia. ( Enat, R; Katz, R; Nagler, A; Pollack, S; Rozenbaum, H; Tatarsky, I, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michowicz, A | 1 |
| Grzegorczyk, K | 1 |
| Nielsen, H | 1 |
| Westerman, EL | 1 |
| De Galocsy, C | 1 |
| Van Ypersele de Strihou, C | 1 |
| Schmitt, J | 1 |
| Jacquier, A | 1 |
| Huttin, B | 1 |
| Lambert, H | 1 |
| Baille, N | 1 |
| Humbert, JC | 1 |
| Raffoux, C | 1 |
| Nakase, K | 1 |
| Itoh, T | 1 |
| Tsuji, K | 1 |
| Miyanishi, E | 1 |
| Morita, K | 1 |
| Shirakawa, S | 1 |
| Uyttenbroeck, W | 1 |
| Korthout, M | 1 |
| De Bock, R | 1 |
| Van Bockstaele, DR | 1 |
| Peetermans, ME | 1 |
| Nagler, A | 1 |
| Rozenbaum, H | 1 |
| Enat, R | 1 |
| Tatarsky, I | 1 |
| Katz, R | 1 |
| Pollack, S | 1 |
1 review available for cimetidine and Pancytopenia
| Article | Year |
|---|---|
[Undesirable effects of the use of cimetidine].
Topics: Aged; Carcinogens; Cerebrovascular Disorders; Cimetidine; Female; Gastritis; Guanidines; Humans; Mal | 1981 |
7 other studies available for cimetidine and Pancytopenia
| Article | Year |
|---|---|
Severe pancytopenia after cimetidine therapy.
Topics: Aged; Cimetidine; Female; Humans; Pancytopenia | 1994 |
Cimetidine, cloxacillin, and pancytopenia.
Topics: Cimetidine; Cloxacillin; Guanidines; Humans; Pancytopenia | 1979 |
Pancytopenia with cimetidine.
Topics: Cimetidine; Guanidines; Humans; Male; Middle Aged; Pancytopenia | 1979 |
[Acute pancytopenia with marrow involvement during treatment with cimetidine (author's transl)].
Topics: Acute Disease; Adult; Bone Marrow Diseases; Cimetidine; Guanidines; Humans; Male; Pancytopenia | 1979 |
[Cimetidine-induced aplastic anemia complicated with nonbacterial thrombotic endocarditis and cerebral infarction].
Topics: Aged; Anemia, Aplastic; Cerebral Infarction; Cimetidine; Endocarditis; Female; Gastritis; Humans; Pa | 1990 |
Cimetidine induced pancytopenia. Effect on human CFU-MIX colony formation.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Cimetidine; Colony-Forming Units Assay; Humans; Male; Pancyto | 1990 |
Immune basis for cimetidine-induced pancytopenia.
Topics: Aged; Cimetidine; Female; Humans; Immunity, Cellular; Leukemia, Myeloid; Lymphocytes; Pancytopenia | 1987 |