cimetidine has been researched along with Pancreatic Neoplasms in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a first description of a pancreatic cancer patient treated with standard chemotherapy and TL-118, an anti-angiogenic combination of 4 drugs that target non-overlapping aspects of the angiogenic process (Provided by Tiltan Pharma Ltd for compassionate use)." | 1.39 | TL-118-anti-angiogenic treatment in pancreatic cancer: a case report. ( Appelbaum, L; Breuer, S; Hubert, A; Maimon, O; Peretz, T, 2013) |
| "New agents are needed to treat pancreatic cancer, one of the most lethal human malignancies." | 1.39 | Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice. ( Alston, N; Constantinides, PP; Huang, L; Mackenzie, GG; Mattheolabakis, G; Ouyang, N; Rigas, B; Vrankova, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Breuer, S | 1 |
| Maimon, O | 1 |
| Appelbaum, L | 1 |
| Peretz, T | 1 |
| Hubert, A | 1 |
| Mackenzie, GG | 1 |
| Huang, L | 1 |
| Alston, N | 1 |
| Ouyang, N | 1 |
| Vrankova, K | 1 |
| Mattheolabakis, G | 1 |
| Constantinides, PP | 1 |
| Rigas, B | 1 |
| Sürücü, O | 1 |
| Middeke, M | 1 |
| Höschele, I | 1 |
| Kalder, J | 1 |
| Hennig, S | 1 |
| Dietz, C | 1 |
| Celik, I | 1 |
| Zollinger, RM | 1 |
| Ellison, EC | 1 |
| Fabri, PJ | 1 |
| Johnson, J | 1 |
| Sparks, J | 1 |
| Carey, LC | 1 |
| Becker, HD | 1 |
| Klempa, I | 1 |
| Encke, A | 1 |
| Classen, M | 1 |
| Feurle, GE | 1 |
| Malesci, A | 1 |
| Bonato, C | 1 |
| Pisegna, JR | 1 |
| Norton, JA | 1 |
| Slimak, GG | 1 |
| Metz, DC | 1 |
| Maton, PN | 1 |
| Gardner, JD | 1 |
| Jensen, RT | 1 |
| Luttwak, EM | 1 |
| Saltz, NJ | 1 |
1 review available for cimetidine and Pancreatic Neoplasms
| Article | Year |
|---|---|
[Zollinger-Ellison syndrome].
Topics: Benzimidazoles; Calcium; Cimetidine; Diarrhea; Duodenal Ulcer; Female; Fluorouracil; Gastrectomy; Ga | 1984 |
1 trial available for cimetidine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; F | 1992 |
7 other studies available for cimetidine and Pancreatic Neoplasms
| Article | Year |
|---|---|
TL-118-anti-angiogenic treatment in pancreatic cancer: a case report.
Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cyclophos | 2013 |
Targeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cimetidine; Drug Synergism; Female; Hum | 2013 |
Tumour growth inhibition of human pancreatic cancer xenografts in SCID mice by cimetidine.
Topics: Animals; Antineoplastic Agents; Cimetidine; Mice; Mice, SCID; Neoplasm Transplantation; Pancreatic N | 2004 |
Primary peptic ulcerations of the jejunum associated with islet cell tumors. Twenty-five-year appraisal.
Topics: Adenoma, Islet Cell; Cimetidine; Follow-Up Studies; Gastrectomy; Gastrins; Humans; Jejunal Diseases; | 1980 |
[Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients].
Topics: Adult; Aged; Cimetidine; Female; Gastrectomy; Gastrins; Histamine H2 Antagonists; Humans; Male; Midd | 1982 |
[Smoke and stomach diseases].
Topics: Antacids; Cimetidine; Duodenal Ulcer; Female; Humans; Lung Neoplasms; Male; Pancreatic Neoplasms; Pe | 1982 |
The progressive Zollinger-Ellison syndrome in multiple endocrine neoplasia.
Topics: Adult; Apudoma; Cimetidine; Follow-Up Studies; Gastrectomy; Gastrinoma; Humans; Male; Middle Aged; M | 1988 |