cimetidine has been researched along with Pancreatic Diseases in 10 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Pancreatic Diseases: Pathological processes of the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is an H2-receptor antagonist that is capable of marked suppression of gastric acid and pepsin secretion." | 2.64 | Cimetidine. H2-receptor blockade in gastrointestinal disease. ( Schlippert, W, 1978) |
| "Useful indications are treatment of gastric ulcer and pnacreatic insufficiency." | 2.36 | H2-receptor antagonists in perspective. ( Cortot, A; Malagelada, JR, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyle, BJ | 1 |
| Long, WB | 1 |
| Balistreri, WF | 1 |
| Widzer, SJ | 1 |
| Huang, N | 1 |
| Malagelada, JR | 5 |
| Cortot, A | 1 |
| Regan, PT | 3 |
| Dimagno, EP | 3 |
| Go, VL | 3 |
| Soulé, JC | 1 |
| Delchier, JC | 1 |
| Bader, JP | 1 |
| Finkelstein, W | 1 |
| Isselbacher, KJ | 1 |
| Schlippert, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Proton Pump Inhibitors (PPI) and Fat Absorption in Subjects With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)[NCT03551691] | Phase 2 | 19 participants (Actual) | Interventional | 2018-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cimetidine and Pancreatic Diseases
| Article | Year |
|---|---|
H2-receptor antagonists in perspective.
Topics: Cimetidine; Double-Blind Method; Duodenal Ulcer; Gastroesophageal Reflux; Gastrointestinal Hemorrhag | 1978 |
Drug-nutrient interactions: use of Cimetidine in malabsorption syndromes.
Topics: Celiac Disease; Cimetidine; Drug Synergism; Gastric Juice; Guanidines; Humans; Malabsorption Syndrom | 1978 |
Drug therapy: Cimetidine.
Topics: Acute Disease; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer | 1978 |
5 trials available for cimetidine and Pancreatic Diseases
| Article | Year |
|---|---|
Effect of cimetidine and pancreatic enzymes on serum and fecal bile acids and fat absorption in cystic fibrosis.
Topics: Adolescent; Adult; Bile Acids and Salts; Celiac Disease; Cimetidine; Cystic Fibrosis; Diet; Drug Com | 1980 |
[Cimetidine, II. Therapeutic trials].
Topics: Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Esophagitis, Peptic; Gastroin | 1978 |
Drug therapy: Cimetidine.
Topics: Acute Disease; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer | 1978 |
Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to pancreatic insufficiency.
Topics: Bicarbonates; Cimetidine; Drug Therapy, Combination; Guanidines; Humans; Malabsorption Syndromes; Pa | 1978 |
Cimetidine. H2-receptor blockade in gastrointestinal disease.
Topics: Animals; Cimetidine; Dogs; Duodenal Ulcer; Gastroesophageal Reflux; Gastrointestinal Diseases; Guani | 1978 |
3 other studies available for cimetidine and Pancreatic Diseases
| Article | Year |
|---|---|
Cimetidine in the USA.
Topics: Cimetidine; Drug Evaluation; Duodenal Ulcer; Guanidines; Humans; Pancreatic Diseases; United States; | 1979 |
Rationale for the use of cimetidine in pancreatic insufficiency.
Topics: Adult; Cimetidine; Duodenal Ulcer; Female; Gastric Juice; Guanidines; Humans; Male; Middle Aged; Pan | 1978 |
Reduced intraluminal bile acid concentrations and fat maldigestion in pancreatic insufficiency: correction by treatment.
Topics: Administration, Oral; Bile Acids and Salts; Cimetidine; Dietary Fats; Digestion; Duodenum; Guanidine | 1979 |