cimetidine has been researched along with Obesity in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effect of cimetidine suspension compared with placebo suspension on weight loss in moderately obese patients taking a 5 MJ/day diet supplemented with dietary fibre." | 9.07 | Cimetidine suspension as adjuvant to energy restricted diet in treating obesity. ( Andersen, T; Breum, L; Gøtzsche, PC; Hilsted, J; Rasmussen, MH, 1993) |
| " Cimetidine dosage in clinical practice should therefore be calculated on the basis of IBW, which better reflects lean body mass, instead of total body weight, which reflects adipose tissue weight in addition to lean body mass." | 6.65 | Cimetidine disposition in obesity. ( Abernethy, DR; Greenblatt, DJ; Gugler, R; Matlis, R, 1984) |
| "Intake of cimetidine suspension 30 minutes before meals in overweight subjects may lead to reduced hunger, less food intake, and subsequent weight loss." | 5.07 | Effect of cimetidine suspension on appetite and weight in overweight subjects. ( Støa-Birketvedt, G, 1993) |
| "To study the effect of cimetidine suspension compared with placebo suspension on weight loss in moderately obese patients taking a 5 MJ/day diet supplemented with dietary fibre." | 5.07 | Cimetidine suspension as adjuvant to energy restricted diet in treating obesity. ( Andersen, T; Breum, L; Gøtzsche, PC; Hilsted, J; Rasmussen, MH, 1993) |
| "Forty-three overweight patients with Type 2 diabetes (age 18-65 y, body mass index (BMI) 27." | 2.69 | Cimetidine reduces weight and improves metabolic control in overweight patients with type 2 diabetes. ( Florholmen, J; Ganss, R; Ingebretsen, OC; Paus, PN; Støa-Birketvedt, G, 1998) |
| "Gastro-oesophageal reflux disease (GERD) is common in obese patients." | 2.41 | Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations. ( Barak, N; Ehrenpreis, ED; Harrison, JR; Sitrin, MD, 2002) |
| "Obesity is associated with considerable morbidity and decreased life expectancy." | 2.41 | Options for pharmacological management of obesity in patients treated with atypical antipsychotics. ( Sanders, TA; Taylor, D; Werneke, U, 2002) |
| "Obesity is a social disease and amounts to a real medical problem." | 1.29 | [Obesity: a multifactorial disorder with difficult long-term treatment]. ( Cotrozzi, G; Fontana, R; Relli, P, 1994) |
| " This same dosage in obese individuals with normal serum creatinine values should result in the same average steady-state serum concentrations." | 1.27 | Cimetidine clearance in the obese. ( Bauer, LA; Dellinger, EP; Edwards, WA; Ferreri, L; Jack, R; Raisys, V; Simonowitz, D; Wareing-Tran, C, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barak, N | 1 |
| Ehrenpreis, ED | 1 |
| Harrison, JR | 1 |
| Sitrin, MD | 1 |
| Werneke, U | 1 |
| Taylor, D | 1 |
| Sanders, TA | 1 |
| Manchikanti, L | 1 |
| Kraus, JW | 1 |
| Edds, SP | 1 |
| de la Pierre, M | 1 |
| Aricò, S | 1 |
| Capussotti, L | 1 |
| Dellepiane, M | 1 |
| Marucci, M | 1 |
| Gandini, G | 1 |
| Imarisio, P | 1 |
| Abernethy, DR | 1 |
| Greenblatt, DJ | 1 |
| Matlis, R | 1 |
| Gugler, R | 1 |
| Stull, DL | 1 |
| Zinn, M | 1 |
| Fales, JT | 1 |
| Lanman, RC | 1 |
| Burich, RL | 1 |
| Wilson, SL | 1 |
| Mantena, NR | 1 |
| Halverson, JD | 1 |
| Printen, KJ | 1 |
| Scott, D | 1 |
| Mason, EE | 1 |
| Cotrozzi, G | 1 |
| Relli, P | 1 |
| Fontana, R | 1 |
| Støa-Birketvedt, G | 2 |
| Rasmussen, MH | 1 |
| Andersen, T | 2 |
| Breum, L | 1 |
| Gøtzsche, PC | 1 |
| Hilsted, J | 1 |
| Garrow, J | 1 |
| Mangtani, P | 1 |
| Seed, P | 1 |
| Paus, PN | 1 |
| Ganss, R | 1 |
| Ingebretsen, OC | 1 |
| Florholmen, J | 1 |
| Højby Rasmussen, M | 1 |
| Lam, AM | 2 |
| Grace, DM | 2 |
| Manninen, PH | 1 |
| Diamond, C | 1 |
| Penny, FJ | 1 |
| Vezina, WC | 1 |
| Bauer, LA | 1 |
| Wareing-Tran, C | 1 |
| Edwards, WA | 1 |
| Raisys, V | 1 |
| Ferreri, L | 1 |
| Jack, R | 1 |
| Dellinger, EP | 1 |
| Simonowitz, D | 1 |
| Ramsey-Stewart, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Effects of Laparoscopic Roux-en-Y Gastric Bypass on Gastro-esophageal Reflux: Clinical Impact of Weakly Acidic Reflux[NCT02618044] | 86 participants (Actual) | Observational | 2006-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cimetidine and Obesity
| Article | Year |
|---|---|
Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.
Topics: Body Composition; Carcinoma; Cimetidine; Esophageal Neoplasms; Gastroesophageal Reflux; Hernia, Hiat | 2002 |
Options for pharmacological management of obesity in patients treated with atypical antipsychotics.
Topics: Amantadine; Antipsychotic Agents; Cimetidine; Cyclobutanes; Fluoxetine; Fructose; Humans; Lactones; | 2002 |
Cimetidine and related drugs in anesthesia.
Topics: Anesthesia, Obstetrical; Child; Cimetidine; Drug Administration Schedule; Emergencies; Female; Gastr | 1982 |
6 trials available for cimetidine and Obesity
| Article | Year |
|---|---|
Cimetidine disposition in obesity.
Topics: Adult; Chromatography, High Pressure Liquid; Cimetidine; Clinical Trials as Topic; Female; Half-Life | 1984 |
Effect of cimetidine suspension on appetite and weight in overweight subjects.
Topics: Adolescent; Adult; Appetite; Blood Pressure; Body Constitution; Body Mass Index; Cimetidine; Diet; D | 1993 |
Cimetidine suspension as adjuvant to energy restricted diet in treating obesity.
Topics: Adolescent; Adult; Blood Pressure; Body Constitution; Body Mass Index; Cimetidine; Combined Modality | 1993 |
Cimetidine and weight loss.
Topics: Cimetidine; Humans; Obesity; Randomized Controlled Trials as Topic; Weight Loss | 1993 |
Cimetidine reduces weight and improves metabolic control in overweight patients with type 2 diabetes.
Topics: Adolescent; Adult; Appetite; Blood Glucose; Body Constitution; Cholecystokinin; Cholesterol, HDL; Ci | 1998 |
The effects of cimetidine and ranitidine with and without metoclopramide on gastric volume and pH in morbidly obese patients.
Topics: Adult; Cimetidine; Female; Gastric Acidity Determination; Gastric Emptying; Gastrointestinal Content | 1986 |
10 other studies available for cimetidine and Obesity
| Article | Year |
|---|---|
[Description of a case of Zollinger-Ellison syndrome].
Topics: Benzodiazepinones; Body Weight; Cimetidine; Diarrhea; Female; Gastrectomy; Gastric Acid; Humans; Mid | 1984 |
The effectiveness of cimetidine as a preoperative medication in increasing gastric pH and decreasing gastric volume in obese patients.
Topics: Adult; Aged; Animals; Cimetidine; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; Male; Mi | 1983 |
Effects of atropine, glycopyrrolate, and cimetidine on gastric secretions in morbidly obese patients.
Topics: Adult; Atropine; Cimetidine; Digestive System Surgical Procedures; Female; Gastric Juice; Glycopyrro | 1981 |
Stomal ulcers after gastric bypass.
Topics: Adult; Age Factors; Antacids; Cimetidine; Female; Gastroenterostomy; Humans; Male; Middle Aged; Obes | 1980 |
[Obesity: a multifactorial disorder with difficult long-term treatment].
Topics: Adolescent; Adult; Albuterol; Appetite Depressants; Biguanides; Cimetidine; Diet, Reducing; Female; | 1994 |
Does cimetidine cause weight loss?
Topics: Cimetidine; Clinical Trials as Topic; Denmark; Double-Blind Method; Humans; Norway; Obesity | 1993 |
Cimetidine and obesity: conflicting evidence.
Topics: Cimetidine; Histamine H2 Antagonists; Humans; Obesity; Randomized Controlled Trials as Topic; Weight | 1999 |
Prophylactic intravenous cimetidine reduces the risk of acid aspiration in morbidly obese patients.
Topics: Adult; Cimetidine; Female; Gastric Acid; Gastric Acidity Determination; Gastric Emptying; Humans; In | 1986 |
Cimetidine clearance in the obese.
Topics: Adult; Body Weight; Cimetidine; Creatinine; Female; Half-Life; Humans; Infusions, Parenteral; Kineti | 1985 |
The perioperative management of morbidly obese patients (a surgeon's perspective).
Topics: Blood Pressure; Cardiovascular Diseases; Cimetidine; Fatty Acids, Nonesterified; Gastric Juice; Huma | 1985 |