Page last updated: 2024-10-25

cimetidine and Nerve Pain

cimetidine has been researched along with Nerve Pain in 6 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"As there is evidence of a possible immunoregulatory role for H2-histamine receptor antagonists, we carried out a prospective randomized trial to evaluate the in vivo and in vitro effect of cimetidine, an H2-blocker, in the treatment of herpes zoster infection."9.06Cimetidine as an immunomodulator in the treatment of herpes zoster. ( Harel, D; Lahat, N; Laor, A; Miller, A, 1989)
"As there is evidence of a possible immunoregulatory role for H2-histamine receptor antagonists, we carried out a prospective randomized trial to evaluate the in vivo and in vitro effect of cimetidine, an H2-blocker, in the treatment of herpes zoster infection."5.06Cimetidine as an immunomodulator in the treatment of herpes zoster. ( Harel, D; Lahat, N; Laor, A; Miller, A, 1989)
" Administration of mirogabalin on a long-term basis is a flexible dosage regimen for patients with PHN."3.01The Clinical Application and Progress of Mirogabalin on Neuropathic Pain as a Novel Selective Gabapentinoids. ( Duan, Y; Li, D; Lu, J; Tang, H, 2023)
"Herpes zoster is an infection caused by reactivation of dormant varicella-zoster virus."2.39Pharmacologic management of herpes zoster and postherpetic neuralgia. ( Mamdani, FS, 1994)
"Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems."1.36Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Hayashi, S1
Nakata, E1
Morita, A1
Mizuno, K1
Yamamura, K1
Kato, A1
Ohashi, K1
Tang, H1
Lu, J1
Duan, Y1
Li, D1
Tachibana, M1
Yamamura, N1
Atiee, GJ1
Hsu, C1
Warren, V1
He, L1
Dishy, V1
Zahir, H1
Albrecht, PJ1
Nalwalk, JW1
Hough, LB1
Mamdani, FS1
Miller, A1
Harel, D1
Laor, A1
Lahat, N1

Reviews

2 reviews available for cimetidine and Nerve Pain

ArticleYear
The Clinical Application and Progress of Mirogabalin on Neuropathic Pain as a Novel Selective Gabapentinoids.
    Mediators of inflammation, 2023, Volume: 2023

    Topics: Analgesics; Bridged Bicyclo Compounds; Cimetidine; Humans; Neuralgia

2023
Pharmacologic management of herpes zoster and postherpetic neuralgia.
    Canadian family physician Medecin de famille canadien, 1994, Volume: 40

    Topics: Acyclovir; Adrenal Cortex Hormones; Algorithms; Analgesics; Anticonvulsants; Antidepressive Agents,

1994

Trials

2 trials available for cimetidine and Nerve Pain

ArticleYear
Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug-drug interaction study.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:10

    Topics: Administration, Oral; Adult; Area Under Curve; Bridged Bicyclo Compounds; Cimetidine; Cross-Over Stu

2018
Cimetidine as an immunomodulator in the treatment of herpes zoster.
    Journal of neuroimmunology, 1989, Volume: 22, Issue:1

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cimetidine; Herpes Zoster; Histamine; Humans; Lymphocyte Ac

1989

Other Studies

2 other studies available for cimetidine and Nerve Pain

ArticleYear
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes,

2010
Efficacy of improgan, a non-opioid analgesic, in neuropathic pain.
    Brain research, 2011, Nov-18, Volume: 1424

    Topics: Analgesics, Non-Narcotic; Animals; Axotomy; Chronic Pain; Cimetidine; Injections, Intraventricular;

2011