cimetidine has been researched along with Nephrotic Syndrome in 6 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Puromycin aminonucleoside (PAN)-induced glomerular injury in rats mimics minimal-change nephrotic syndrome (NS) in humans." | 3.72 | Role of cytochrome P450 2B1 in puromycin aminonucleoside-induced cytotoxicity to glomerular epithelial cells. ( Baliga, M; Baliga, R; Bigler, SA; Liu, H, 2003) |
| "We have recently demonstrated an important pathogenic role for glomerular catalytic iron in the puromycin aminonucleoside (PAN) induced minimal change nephrotic syndrome (MCNS)." | 3.71 | Cytochrome P-450 as a source of catalytic iron in minimal change nephrotic syndrome in rats. ( Baliga, R; Liu, H; Shah, SV, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 2 |
| Baliga, M | 1 |
| Bigler, SA | 1 |
| Baliga, R | 2 |
| Maher, JF | 1 |
| Milford, DV | 1 |
| Butler, N | 1 |
| Clarke, R | 1 |
| Vaid, J | 1 |
| Shah, SV | 1 |
| van Acker, BA | 1 |
| Koomen, GC | 1 |
| Koopman, MG | 1 |
| Krediet, RT | 1 |
| Arisz, L | 1 |
| Schnaper, HW | 1 |
| Aune, TM | 1 |
| Roby, RK | 1 |
1 review available for cimetidine and Nephrotic Syndrome
| Article | Year |
|---|---|
Clinicopathologic spectrum of drug nephrotoxicity.
Topics: Aminoglycosides; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents; | 1984 |
5 other studies available for cimetidine and Nephrotic Syndrome
| Article | Year |
|---|---|
Role of cytochrome P450 2B1 in puromycin aminonucleoside-induced cytotoxicity to glomerular epithelial cells.
Topics: Animals; Cells, Cultured; Cimetidine; Cytochrome P-450 CYP2B1; Disease Models, Animal; Dose-Response | 2003 |
Reversible hepatic dysfunction in association with cyclophosphamide therapy.
Topics: Child, Preschool; Cimetidine; Cyclophosphamide; Drug Interactions; Female; Humans; Jaundice; Liver; | 1995 |
Cytochrome P-450 as a source of catalytic iron in minimal change nephrotic syndrome in rats.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhi | 2001 |
Discrepancy between circadian rhythms of inulin and creatinine clearance.
Topics: Adult; Aged; Cimetidine; Circadian Rhythm; Creatinine; Female; Glomerular Filtration Rate; Humans; I | 1992 |
A role for histamine type II (H-2) receptor binding in production of the lymphokine, soluble immune response suppressor (SIRS).
Topics: Antibody Formation; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cimetidine; Concanav | 1987 |