cimetidine has been researched along with Nephritis, Interstitial in 25 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Nephritis, Interstitial: Inflammation of the interstitial tissue of the kidney. This term is generally used for primary inflammation of KIDNEY TUBULES and/or surrounding interstitium. For primary inflammation of glomerular interstitium, see GLOMERULONEPHRITIS. Infiltration of the inflammatory cells into the interstitial compartment results in EDEMA, increased spaces between the tubules, and tubular renal dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a case of acute tubulointerstitial nephritis (ATIN) that developed in a 63-year-old man who had been taking cimetidine for treatment of a gastric ulcer." | 7.70 | A case of cimetidine-induced acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody. ( Hirato, J; Hiromura, K; Kitahara, T; Maezawa, A; Naruse, T; Nojima, Y; Sato, S; Sugawara, M; Ueki, K; Yano, S, 1999) |
| "A biopsy-proved case of acute interstitial nephritis related to the use of cimetidine in duodenal ulcer disease is presented." | 7.66 | Acute interstitial nephritis related to cimetidine therapy. ( McGowan, WR; Vermillion, SE, 1980) |
| "Acute tubulointerstitial nephritis (ATIN), which is often drug-induced, is a frequent cause of kidney injury." | 6.72 | Acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody following cimetidine treatment: a case report. ( Kanzaki, G; Koike, K; Maruyama, Y; Matsuo, N; Morimoto, K; Niikura, T; Tsuboi, N; Yokoo, T, 2021) |
| "Cimetidine is a histamine H2-receptor antagonist." | 6.38 | [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine]. ( Koarada, S; Nagano, Y; Sakemi, T; Syouno, Y; Watanabe, T, 1992) |
| "The cimetidine titer was positive, at 2,537 cpm." | 5.33 | Cimetidine-induced tubulointerstitial nephritis with both MPO-ANCA and PR3-ANCA. ( Imanishi, Y; Inaba, M; Ishimura, E; Jono, S; Matsumoto, N; Nishizawa, Y; Tsuchida, T; Ueda, H; Yunoki, T, 2005) |
| " Although mild elevation of serum creatinine level following the administration of cimetidine is relatively common, acute interstitial nephritis (AIN) is a rare hypersensitivity reaction." | 4.81 | Nephrotoxicity and hepatotoxicity of histamine H2 receptor antagonists. ( Fisher, AA; Le Couteur, DG, 2001) |
| "We present a case of acute tubulointerstitial nephritis (ATIN) that developed in a 63-year-old man who had been taking cimetidine for treatment of a gastric ulcer." | 3.70 | A case of cimetidine-induced acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody. ( Hirato, J; Hiromura, K; Kitahara, T; Maezawa, A; Naruse, T; Nojima, Y; Sato, S; Sugawara, M; Ueki, K; Yano, S, 1999) |
| "A biopsy-proved case of acute interstitial nephritis related to the use of cimetidine in duodenal ulcer disease is presented." | 3.66 | Acute interstitial nephritis related to cimetidine therapy. ( McGowan, WR; Vermillion, SE, 1980) |
| "Acute tubulointerstitial nephritis (ATIN), which is often drug-induced, is a frequent cause of kidney injury." | 2.72 | Acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody following cimetidine treatment: a case report. ( Kanzaki, G; Koike, K; Maruyama, Y; Matsuo, N; Morimoto, K; Niikura, T; Tsuboi, N; Yokoo, T, 2021) |
| "Cimetidine is a histamine H2-receptor antagonist." | 2.38 | [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine]. ( Koarada, S; Nagano, Y; Sakemi, T; Syouno, Y; Watanabe, T, 1992) |
| "The cimetidine titer was positive, at 2,537 cpm." | 1.33 | Cimetidine-induced tubulointerstitial nephritis with both MPO-ANCA and PR3-ANCA. ( Imanishi, Y; Inaba, M; Ishimura, E; Jono, S; Matsumoto, N; Nishizawa, Y; Tsuchida, T; Ueda, H; Yunoki, T, 2005) |
| "Pain was predominant in the hip area, disappeared within a few days after withdrawal and recurred three weeks after resuming therapy." | 1.27 | Recurrent myalgias associated with cimetidine. ( Cabanne, JF; Dubot, P; Labeeuw, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (72.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morimoto, K | 1 |
| Kanzaki, G | 1 |
| Niikura, T | 1 |
| Koike, K | 1 |
| Matsuo, N | 1 |
| Maruyama, Y | 1 |
| Tsuboi, N | 1 |
| Yokoo, T | 1 |
| Ueda, H | 1 |
| Ishimura, E | 1 |
| Yunoki, T | 1 |
| Tsuchida, T | 1 |
| Matsumoto, N | 1 |
| Jono, S | 1 |
| Imanishi, Y | 1 |
| Inaba, M | 1 |
| Nishizawa, Y | 1 |
| Kaye, M | 1 |
| Gagnon, RF | 1 |
| Watson, AJ | 1 |
| Dalbow, MH | 1 |
| Stachura, I | 1 |
| Fragola, JA | 1 |
| Rubin, MF | 1 |
| Watson, RM | 1 |
| Bourke, E | 1 |
| Potter, PH | 1 |
| Westby, RG | 1 |
| Tsekova, D | 1 |
| Belovezhdov, N | 1 |
| Santoro, JJ | 2 |
| Pitone, JM | 2 |
| Biondi, RJ | 2 |
| Chiesa, JC | 2 |
| Pecora, AA | 2 |
| Kaye, WA | 1 |
| Passero, MA | 1 |
| Solomon, RJ | 1 |
| Johnson, LA | 1 |
| Davis, TG | 1 |
| Pickett, DL | 1 |
| Schlosser, JH | 1 |
| Rudnick, MR | 1 |
| Bastl, CP | 1 |
| Elfenbein, IB | 1 |
| Sirota, RA | 1 |
| Yudis, M | 1 |
| Narins, RG | 1 |
| Hake, DH | 1 |
| Richman, AV | 1 |
| Narayan, JL | 1 |
| Hirschfield, JS | 1 |
| Handa, SP | 2 |
| McGowan, WR | 1 |
| Vermillion, SE | 1 |
| Kitahara, T | 1 |
| Hiromura, K | 1 |
| Sugawara, M | 1 |
| Hirato, J | 1 |
| Sato, S | 1 |
| Ueki, K | 1 |
| Maezawa, A | 1 |
| Yano, S | 1 |
| Nojima, Y | 1 |
| Naruse, T | 1 |
| Fisher, AA | 1 |
| Le Couteur, DG | 1 |
| Koarada, S | 1 |
| Nagano, Y | 1 |
| Sakemi, T | 1 |
| Syouno, Y | 1 |
| Watanabe, T | 1 |
| Mullen, PJ | 1 |
| Ozawa, TT | 1 |
| Smith, P | 1 |
| Vance, D | 1 |
| Moore, N | 1 |
| Lackey, L | 1 |
| Ma, KW | 1 |
| Labeeuw, M | 1 |
| Cabanne, JF | 1 |
| Dubot, P | 1 |
| Ali, N | 1 |
| Hamilton, DV | 1 |
| Pryor, JS | 1 |
| O'Regan, M | 1 |
| Roberts, PF | 1 |
| Seidelin, R | 1 |
4 reviews available for cimetidine and Nephritis, Interstitial
| Article | Year |
|---|---|
Acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody following cimetidine treatment: a case report.
Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil | 2021 |
[Cimetidine and the kidneys].
Topics: beta 2-Microglobulin; Cimetidine; Creatinine; Dose-Response Relationship, Drug; Gastric Mucosa; Glom | 1983 |
Nephrotoxicity and hepatotoxicity of histamine H2 receptor antagonists.
Topics: Cimetidine; Creatinine; Duodenal Ulcer; Histamine; Histamine H2 Antagonists; Humans; Liver Failure; | 2001 |
[A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine].
Topics: Acute Kidney Injury; Cimetidine; Female; Humans; Kidney; Middle Aged; Nephritis, Interstitial | 1992 |
1 trial available for cimetidine and Nephritis, Interstitial
| Article | Year |
|---|---|
Evaluation of a worldwide spontaneous reporting system with cimetidine.
Topics: Anticoagulants; Cimetidine; Clinical Trials as Topic; Confusion; Drug Synergism; Guanidines; Humans; | 1980 |
20 other studies available for cimetidine and Nephritis, Interstitial
| Article | Year |
|---|---|
Cimetidine-induced tubulointerstitial nephritis with both MPO-ANCA and PR3-ANCA.
Topics: Aged; Anti-Ulcer Agents; Antibodies, Antineutrophil Cytoplasmic; Cimetidine; Humans; Male; Myeloblas | 2005 |
Acute allergic interstitial nephritis and eosinophiluria.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Drug Hypersensitivity; Eosinophilia; Histamine | 2008 |
Immunologic studies in cimetidine-induced nephropathy and polymyositis.
Topics: Adult; B-Lymphocytes; Biopsy; Cell Migration Inhibition; Cimetidine; Drug Hypersensitivity; Guanidin | 1983 |
Interstitial nephritis after cimetidine but not ranitidine.
Topics: Aged; Cimetidine; Esophagitis, Peptic; Furans; Guanidines; Humans; Male; Nephritis, Interstitial; Ra | 1983 |
Cimetidine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Female; Guanidines; Humans; Nephritis, Interstitial | 1982 |
Cimetidine-induced interstitial nephritis with response to prednisone therapy.
Topics: Acute Disease; Aged; Cimetidine; Dyspepsia; Female; Guanidines; Humans; Nephritis, Interstitial; Pre | 1983 |
Cimetidine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Guanidines; Humans; Male; Middle Aged; Nephritis, Interstitia | 1982 |
Cimetidine-induced acute interstitial nephritis.
Topics: Aged; Cimetidine; Creatinine; Female; Guanidines; Humans; Nephritis, Interstitial | 1982 |
Interstitial nephritis and cimetidine.
Topics: Cimetidine; Fever; Guanidines; Humans; Male; Middle Aged; Nephritis, Interstitial; Recurrence | 1981 |
Acute interstitial nephritis and acute renal failure associated with cimetidine therapy.
Topics: Acute Kidney Injury; Aged; Biopsy; Cimetidine; Eosinophils; Guanidines; Humans; Kidney; Male; Nephri | 1981 |
Interstitial nephritis induced by cimetidine.
Topics: Adult; Cimetidine; Guanidines; Humans; Male; Nephritis, Interstitial | 1981 |
Acute interstitial nephritis related to cimetidine therapy.
Topics: Adult; Biopsy; Cimetidine; Drug Hypersensitivity; Duodenal Ulcer; Guanidines; Humans; Kidney; Male; | 1980 |
A case of cimetidine-induced acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody.
Topics: Anti-Ulcer Agents; Antibodies, Antineutrophil Cytoplasmic; Cimetidine; Humans; Kidney; Male; Middle | 1999 |
Polyuria and weight-loss associated with cimetidine.
Topics: Cimetidine; Humans; Male; Middle Aged; Nephritis, Interstitial; Polyuria; Weight Loss | 1992 |
Acute interstitial nephritis induced by cimetidine.
Topics: Acute Disease; Cimetidine; Humans; Male; Middle Aged; Nephritis, Interstitial | 1987 |
Cimetidine and the kidney.
Topics: Acute Kidney Injury; Cimetidine; Graft Rejection; Humans; Kidney Diseases; Nephritis, Interstitial | 1986 |
Recurrent myalgias associated with cimetidine.
Topics: Cimetidine; Duodenal Ulcer; Female; Humans; Middle Aged; Muscles; Nephritis, Interstitial; Pain; Rec | 1986 |
Drug-induced acute interstitial nephritis: report of 10 cases.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory | 1986 |
Safety of cimetidine.
Topics: Aged; Cimetidine; Female; Humans; Nephritis, Interstitial | 1985 |
Safety of cimetidine.
Topics: Adult; Cimetidine; Female; Humans; Nephritis, Interstitial; Urologic Diseases | 1985 |