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cimetidine and Myocardial Infarction

cimetidine has been researched along with Myocardial Infarction in 12 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear."7.81Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015)
"The effects of two H2-receptor antagonists, ranitidine (Ran) and cimetidine (Cim), on the ventricular fibrillation threshold (VFT) and dispersion of the refractory period in animals with early acute myocardial ischemia induced by coronary artery ligation (CAL) were studied."7.67[Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia]. ( Luo, XX; Tan, YH, 1989)
"In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction."7.67The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987)
"Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear."3.81Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015)
"The effects of two H2-receptor antagonists, ranitidine (Ran) and cimetidine (Cim), on the ventricular fibrillation threshold (VFT) and dispersion of the refractory period in animals with early acute myocardial ischemia induced by coronary artery ligation (CAL) were studied."3.67[Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia]. ( Luo, XX; Tan, YH, 1989)
"In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction."3.67The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, L1
Hong, T1
Lin, J1
Ding, S1
Huang, Z1
Chen, J1
Jia, J1
Zou, Y1
Wang, TC1
Yang, X1
Ge, J1
Hubbard, CR1
Blankenship, JC1
Scott, TD1
Skelding, KA1
Berger, PB1
Sheng-Wen Wang, S1
Tsai, SS1
Hsu, PC1
Yang, CY1
Wu, DC1
Yang, YX1
Lewis, JD1
Baumann, G1
Felix, SB1
Schrader, J1
Heidecke, CD1
Riess, G1
Erhardt, WD1
Ludwig, L1
Loher, U1
Sebening, F1
Blömer, H1
Salive, ME1
Jones, CA1
Guralnik, JM1
Agodoa, LY1
Pahor, M1
Wallace, RB1
Lada, W1
Nagy, V1
Csürös, L1
Iskum, M1
Luo, XX1
Tan, YH1
Li, YS1
Fu, SX1
Li, CG1
Berk, SI1
Gal, P1
Bauman, JL1
Douglas, JB1
McCue, JD1
Powell, JR1
Engelhardt, D1
Karl, R1
Kolb, HJ1
Inthorn, D1
König, N1
Büll, U1
Hölzel, D1

Reviews

2 reviews available for cimetidine and Myocardial Infarction

ArticleYear
Prevention and treatment of stress ulcers in critically ill patients.
    Seminars in gastrointestinal disease, 2003, Volume: 14, Issue:1

    Topics: Aged; Anti-Ulcer Agents; Cimetidine; Critical Illness; Female; Gastric Mucosa; Gastrointestinal Hemo

2003
[Imidazoline receptors and use of drug blocking receptors I1].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1996, Volume: 1, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antihypertensive Agents; Arrhythmias, Cardi

1996

Trials

1 trial available for cimetidine and Myocardial Infarction

ArticleYear
[Comparison between cimetidine-pirenzepine and antacids for the prevention of stress hemorrhage in intensive care patients. A controlled clinical study on 125 patients].
    Deutsche medizinische Wochenschrift (1946), 1985, Jun-07, Volume: 110, Issue:23

    Topics: Adult; Aged; Antacids; Benzodiazepinones; Chromium Radioisotopes; Cimetidine; Clinical Trials as Top

1985

Other Studies

9 other studies available for cimetidine and Myocardial Infarction

ArticleYear
Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis.
    Scientific reports, 2015, Aug-17, Volume: 5

    Topics: Acute Disease; Animals; Apoptosis; Cell Line; Cimetidine; Creatine Kinase, MB Form; Disease Models,

2015
Emergency pretreatment for contrast allergy before direct percutaneous coronary intervention for ST-elevation myocardial infarction.
    The American journal of cardiology, 2008, Dec-01, Volume: 102, Issue:11

    Topics: Acetates; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents; Antiemetics; Cimetidine; Contras

2008
Concomitant use of clopidogrel and proton pump inhibitors or cimetidine after acute myocardial infarction would increase the risk of re-infarction.
    The American journal of gastroenterology, 2009, Volume: 104, Issue:12

    Topics: Alleles; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cimetidine; Clopidogrel; Cytochrome P-450

2009
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1981, Volume: 179, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cimetidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Fema

1981
Serum creatinine levels in older adults: relationship with health status and medications.
    Age and ageing, 1995, Volume: 24, Issue:2

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Black People; Cardiovascular Agents; Cimetidine

1995
Examination of the effect of histodil prophylaxis in infarction patients with inhibited haemostasis.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:2

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anticoagulants; Cimetidine; Female; Gastrointestinal

1990
[Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:3

    Topics: Animals; Cimetidine; Electrocardiography; Female; Male; Myocardial Infarction; Rabbits; Ranitidine;

1989
[Arrhythmogenic effects of histamine on ischemic hearts of guinea pigs].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Cricetinae; Female; Heart Rate; Histami

1987
The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction.
    International journal of cardiology, 1987, Volume: 14, Issue:1

    Topics: Administration, Oral; Aged; Cimetidine; Drug Interactions; Humans; Lidocaine; Male; Middle Aged; Myo

1987