cimetidine has been researched along with Myocardial Infarction in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear." | 7.81 | Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015) |
| "The effects of two H2-receptor antagonists, ranitidine (Ran) and cimetidine (Cim), on the ventricular fibrillation threshold (VFT) and dispersion of the refractory period in animals with early acute myocardial ischemia induced by coronary artery ligation (CAL) were studied." | 7.67 | [Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia]. ( Luo, XX; Tan, YH, 1989) |
| "In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction." | 7.67 | The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987) |
| "Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear." | 3.81 | Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis. ( Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y, 2015) |
| "The effects of two H2-receptor antagonists, ranitidine (Ran) and cimetidine (Cim), on the ventricular fibrillation threshold (VFT) and dispersion of the refractory period in animals with early acute myocardial ischemia induced by coronary artery ligation (CAL) were studied." | 3.67 | [Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia]. ( Luo, XX; Tan, YH, 1989) |
| "In this study, we prospectively evaluated the effect of oral cimetidine on serum lidocaine concentrations in 6 patients with suspected myocardial infarction." | 3.67 | The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction. ( Bauman, JL; Berk, SI; Douglas, JB; Gal, P; McCue, JD; Powell, JR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, L | 1 |
| Hong, T | 1 |
| Lin, J | 1 |
| Ding, S | 1 |
| Huang, Z | 1 |
| Chen, J | 1 |
| Jia, J | 1 |
| Zou, Y | 1 |
| Wang, TC | 1 |
| Yang, X | 1 |
| Ge, J | 1 |
| Hubbard, CR | 1 |
| Blankenship, JC | 1 |
| Scott, TD | 1 |
| Skelding, KA | 1 |
| Berger, PB | 1 |
| Sheng-Wen Wang, S | 1 |
| Tsai, SS | 1 |
| Hsu, PC | 1 |
| Yang, CY | 1 |
| Wu, DC | 1 |
| Yang, YX | 1 |
| Lewis, JD | 1 |
| Baumann, G | 1 |
| Felix, SB | 1 |
| Schrader, J | 1 |
| Heidecke, CD | 1 |
| Riess, G | 1 |
| Erhardt, WD | 1 |
| Ludwig, L | 1 |
| Loher, U | 1 |
| Sebening, F | 1 |
| Blömer, H | 1 |
| Salive, ME | 1 |
| Jones, CA | 1 |
| Guralnik, JM | 1 |
| Agodoa, LY | 1 |
| Pahor, M | 1 |
| Wallace, RB | 1 |
| Lada, W | 1 |
| Nagy, V | 1 |
| Csürös, L | 1 |
| Iskum, M | 1 |
| Luo, XX | 1 |
| Tan, YH | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Li, CG | 1 |
| Berk, SI | 1 |
| Gal, P | 1 |
| Bauman, JL | 1 |
| Douglas, JB | 1 |
| McCue, JD | 1 |
| Powell, JR | 1 |
| Engelhardt, D | 1 |
| Karl, R | 1 |
| Kolb, HJ | 1 |
| Inthorn, D | 1 |
| König, N | 1 |
| Büll, U | 1 |
| Hölzel, D | 1 |
2 reviews available for cimetidine and Myocardial Infarction
| Article | Year |
|---|---|
Prevention and treatment of stress ulcers in critically ill patients.
Topics: Aged; Anti-Ulcer Agents; Cimetidine; Critical Illness; Female; Gastric Mucosa; Gastrointestinal Hemo | 2003 |
[Imidazoline receptors and use of drug blocking receptors I1].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antihypertensive Agents; Arrhythmias, Cardi | 1996 |
1 trial available for cimetidine and Myocardial Infarction
| Article | Year |
|---|---|
[Comparison between cimetidine-pirenzepine and antacids for the prevention of stress hemorrhage in intensive care patients. A controlled clinical study on 125 patients].
Topics: Adult; Aged; Antacids; Benzodiazepinones; Chromium Radioisotopes; Cimetidine; Clinical Trials as Top | 1985 |
9 other studies available for cimetidine and Myocardial Infarction
| Article | Year |
|---|---|
Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis.
Topics: Acute Disease; Animals; Apoptosis; Cell Line; Cimetidine; Creatine Kinase, MB Form; Disease Models, | 2015 |
Emergency pretreatment for contrast allergy before direct percutaneous coronary intervention for ST-elevation myocardial infarction.
Topics: Acetates; Angioplasty, Balloon, Coronary; Anti-Inflammatory Agents; Antiemetics; Cimetidine; Contras | 2008 |
Concomitant use of clopidogrel and proton pump inhibitors or cimetidine after acute myocardial infarction would increase the risk of re-infarction.
Topics: Alleles; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cimetidine; Clopidogrel; Cytochrome P-450 | 2009 |
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Fema | 1981 |
Serum creatinine levels in older adults: relationship with health status and medications.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Black People; Cardiovascular Agents; Cimetidine | 1995 |
Examination of the effect of histodil prophylaxis in infarction patients with inhibited haemostasis.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anticoagulants; Cimetidine; Female; Gastrointestinal | 1990 |
[Effects of ranitidine and cimetidine on ventricular fibrillation threshold and dispersion of refractory period in early myocardial ischemia].
Topics: Animals; Cimetidine; Electrocardiography; Female; Male; Myocardial Infarction; Rabbits; Ranitidine; | 1989 |
[Arrhythmogenic effects of histamine on ischemic hearts of guinea pigs].
Topics: Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Cricetinae; Female; Heart Rate; Histami | 1987 |
The effect of oral cimetidine on total and unbound serum lidocaine concentrations in patients with suspected myocardial infarction.
Topics: Administration, Oral; Aged; Cimetidine; Drug Interactions; Humans; Lidocaine; Male; Middle Aged; Myo | 1987 |