cimetidine has been researched along with Motor Neuron Disease in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the analysis the presence of a peptic ulcer in patients after 1976 was taken as a proxy for cimetidine (and ranitidine) use." | 7.68 | Peptic ulcer, cimetidine, and motor neurone disease--a record linkage study. ( Goldacre, MJ; Seagroatt, V; Vessey, MP; Yeates, D, 1993) |
| " In the analysis the presence of a peptic ulcer in patients after 1976 was taken as a proxy for cimetidine (and ranitidine) use." | 3.68 | Peptic ulcer, cimetidine, and motor neurone disease--a record linkage study. ( Goldacre, MJ; Seagroatt, V; Vessey, MP; Yeates, D, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vessey, MP | 1 |
| Goldacre, MJ | 1 |
| Seagroatt, V | 1 |
| Yeates, D | 1 |
1 other study available for cimetidine and Motor Neuron Disease
| Article | Year |
|---|---|
Peptic ulcer, cimetidine, and motor neurone disease--a record linkage study.
Topics: Cimetidine; Confidence Intervals; Humans; Medical Record Linkage; Motor Neuron Disease; Multiple Scl | 1993 |