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cimetidine and Milk-Alkali Syndrome

cimetidine has been researched along with Milk-Alkali Syndrome in 15 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Because of the contradictory results formerly published as regards the effect of cimetidine in primary hyperparathyroidism, we have studied the effect of cimetidine at the daily dose of 1200 mg in 14 cases of primary hyperparathyroidism."7.67[Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium]. ( Bourdeau, A; Fournier, A; Grégoire, I; Gueris, J; Hardin, JM; Hervé, MA; Line, D; Pruna, A; Sebert, JL, 1984)
"In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally."7.66Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980)
"Cimetidine has been reported as suppressing the excess parathyroid hormone secretion and hypercalcaemia seen in hyperparathyroidism."7.66Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism. ( Benton, KG; Mallett, RB; Sainsbury, R, 1981)
" Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide."4.76Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980)
"Because of the contradictory results formerly published as regards the effect of cimetidine in primary hyperparathyroidism, we have studied the effect of cimetidine at the daily dose of 1200 mg in 14 cases of primary hyperparathyroidism."3.67[Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium]. ( Bourdeau, A; Fournier, A; Grégoire, I; Gueris, J; Hardin, JM; Hervé, MA; Line, D; Pruna, A; Sebert, JL, 1984)
"In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally."3.66Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980)
"Cimetidine has been reported as suppressing the excess parathyroid hormone secretion and hypercalcaemia seen in hyperparathyroidism."3.66Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism. ( Benton, KG; Mallett, RB; Sainsbury, R, 1981)
"Lastly, the nonspecific arrhythmias associated with endocrine disturbances are outlined."2.37Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances. ( Commerford, PJ; Lloyd, EA, 1984)
" The intimate relationship of the bioavailability of cimetidine and its effect in primary hyperparathyroidism is clearly demonstrated."2.37Hyperparathyroid crisis reviewed: a role for parenteral cimetidine? ( Ackroyd, FW; Garcia, M; Glick, H; Goldstone, RJ; Minervini, D; Sherwood, JK, 1986)
"Primary hyperparathyroidism has become a relatively common endocrine disorder."2.36The medical management of primary hyperparathyroidism. ( Bilezikian, JP, 1982)
" Interactions at the absorption level can be avoided by administering the antacid one hour after intake of the other drugs (one hour after meals) which is also the optimum dosing schedule to ensure good antacid effect."1.27[Metabolic effects of antacids and interactions with other drugs]. ( Gugler, R; Musch, E, 1983)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199015 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sherwood, JK2
Ackroyd, FW2
Garcia, M2
Awoke, S1
Lawrence, GD1
Ljunghall, S1
Akerström, G1
Rudberg, C1
Wide, L1
Johansson, H1
Line, D1
Sebert, JL1
Grégoire, I1
Gueris, J1
Pruna, A1
Bourdeau, A1
Hervé, MA1
Hardin, JM1
Fournier, A1
Brennan, MF1
Commerford, PJ1
Lloyd, EA1
Gugler, R1
Musch, E1
Mallory, A1
Kern, F1
Bilezikian, JP1
Mallett, RB1
Sainsbury, R1
Benton, KG1
Lanier, D1
Favre, H1
Jacob, AI1
Bourgoignie, JJ1
Sasaki, H1
Miyake, K1
Okumura, M1
Eimoto, T1
Glick, H1
Minervini, D1
Goldstone, RJ1
Vellar, D1
Henderson, M1
Vellar, ID1
Desmond, P1
Sarosdy, MF1
Saylor, R1
Dittman, W1
Cruz, AB1
Gaskill, HV1
Banowsky, LH1

Reviews

5 reviews available for cimetidine and Milk-Alkali Syndrome

ArticleYear
Primary hyperparathyroidism.
    Advances in surgery, 1983, Volume: 16

    Topics: Adenoma; Aged; Cimetidine; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Male;

1983
Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances.
    The Medical clinics of North America, 1984, Volume: 68, Issue:5

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Cimetidine; Digitalis Glycoside

1984
Drug-induced pancreatitis: a critical review.
    Gastroenterology, 1980, Volume: 78, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch

1980
The medical management of primary hyperparathyroidism.
    Annals of internal medicine, 1982, Volume: 96, Issue:2

    Topics: Calcitonin; Calcium, Dietary; Cimetidine; Diphosphonates; Estrogens; Humans; Hypercalcemia; Hyperpar

1982
Hyperparathyroid crisis reviewed: a role for parenteral cimetidine?
    The American surgeon, 1986, Volume: 52, Issue:6

    Topics: Adult; Aged; Calcium; Cimetidine; Emergencies; Female; Humans; Hypercalcemia; Hyperparathyroidism; M

1986

Other Studies

10 other studies available for cimetidine and Milk-Alkali Syndrome

ArticleYear
Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism.
    Lancet (London, England), 1980, Mar-22, Volume: 1, Issue:8169

    Topics: Adenoma; Administration, Oral; Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperpar

1980
Cimetidine and hyperparathyroidism.
    Lancet (London, England), 1980, May-24, Volume: 1, Issue:8178

    Topics: Adult; Calcium; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Male; Mi

1980
Cimetidine in primary hyperparathyroidism.
    Lancet (London, England), 1980, Aug-30, Volume: 2, Issue:8192

    Topics: Cimetidine; Drug Evaluation; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Male

1980
[Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium].
    Presse medicale (Paris, France : 1983), 1984, Mar-24, Volume: 13, Issue:12

    Topics: Adolescent; Adult; Aged; Calcium; Child; Cimetidine; Female; Humans; Hypercalcemia; Hyperparathyroid

1984
[Metabolic effects of antacids and interactions with other drugs].
    Zeitschrift fur Gastroenterologie, 1983, Volume: 21 Suppl

    Topics: Absorption; Alkalosis; Antacids; Cimetidine; Drug Interactions; Gastric Acid; Humans; Hypercalcemia;

1983
Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism.
    Postgraduate medical journal, 1981, Volume: 57, Issue:666

    Topics: Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Parathyroid Hormon

1981
Cimetidine therapy for severe hypercalcemia in two chronic hemodialysis patients.
    Annals of internal medicine, 1980, Volume: 93, Issue:4

    Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; Middle

1980
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1988, Volume: 77, Issue:1

    Topics: Adenoma; Aged; Alkaline Phosphatase; Cimetidine; Etidronic Acid; Humans; Hypercalcemia; Hyperparathy

1988
The Zollinger-Ellison syndrome: a review of the St Vincent's Hospital, Melbourne experience.
    The Australian and New Zealand journal of surgery, 1985, Volume: 55, Issue:5

    Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Female; Gastric Acid; Humans; Hypercal

1985
Upper gastrointestinal bleeding following renal transplantation.
    Urology, 1985, Volume: 26, Issue:4

    Topics: Antacids; Blood Transfusion; Calcium; Cimetidine; Embolization, Therapeutic; Gastrointestinal Hemorr

1985