cimetidine has been researched along with Milk-Alkali Syndrome in 15 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because of the contradictory results formerly published as regards the effect of cimetidine in primary hyperparathyroidism, we have studied the effect of cimetidine at the daily dose of 1200 mg in 14 cases of primary hyperparathyroidism." | 7.67 | [Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium]. ( Bourdeau, A; Fournier, A; Grégoire, I; Gueris, J; Hardin, JM; Hervé, MA; Line, D; Pruna, A; Sebert, JL, 1984) |
| "In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally." | 7.66 | Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980) |
| "Cimetidine has been reported as suppressing the excess parathyroid hormone secretion and hypercalcaemia seen in hyperparathyroidism." | 7.66 | Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism. ( Benton, KG; Mallett, RB; Sainsbury, R, 1981) |
| " Less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide." | 4.76 | Drug-induced pancreatitis: a critical review. ( Kern, F; Mallory, A, 1980) |
| "Because of the contradictory results formerly published as regards the effect of cimetidine in primary hyperparathyroidism, we have studied the effect of cimetidine at the daily dose of 1200 mg in 14 cases of primary hyperparathyroidism." | 3.67 | [Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium]. ( Bourdeau, A; Fournier, A; Grégoire, I; Gueris, J; Hardin, JM; Hervé, MA; Line, D; Pruna, A; Sebert, JL, 1984) |
| "In twelve patients with primary hyperparathyroidism the raised parathyroid hormone (PTH) levels consistently returned to normal with cimetidine ("Tagamet"), 300 mg four times a day, orally." | 3.66 | Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism. ( Ackroyd, FW; Garcia, M; Sherwood, JK, 1980) |
| "Cimetidine has been reported as suppressing the excess parathyroid hormone secretion and hypercalcaemia seen in hyperparathyroidism." | 3.66 | Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism. ( Benton, KG; Mallett, RB; Sainsbury, R, 1981) |
| "Lastly, the nonspecific arrhythmias associated with endocrine disturbances are outlined." | 2.37 | Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances. ( Commerford, PJ; Lloyd, EA, 1984) |
| " The intimate relationship of the bioavailability of cimetidine and its effect in primary hyperparathyroidism is clearly demonstrated." | 2.37 | Hyperparathyroid crisis reviewed: a role for parenteral cimetidine? ( Ackroyd, FW; Garcia, M; Glick, H; Goldstone, RJ; Minervini, D; Sherwood, JK, 1986) |
| "Primary hyperparathyroidism has become a relatively common endocrine disorder." | 2.36 | The medical management of primary hyperparathyroidism. ( Bilezikian, JP, 1982) |
| " Interactions at the absorption level can be avoided by administering the antacid one hour after intake of the other drugs (one hour after meals) which is also the optimum dosing schedule to ensure good antacid effect." | 1.27 | [Metabolic effects of antacids and interactions with other drugs]. ( Gugler, R; Musch, E, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sherwood, JK | 2 |
| Ackroyd, FW | 2 |
| Garcia, M | 2 |
| Awoke, S | 1 |
| Lawrence, GD | 1 |
| Ljunghall, S | 1 |
| Akerström, G | 1 |
| Rudberg, C | 1 |
| Wide, L | 1 |
| Johansson, H | 1 |
| Line, D | 1 |
| Sebert, JL | 1 |
| Grégoire, I | 1 |
| Gueris, J | 1 |
| Pruna, A | 1 |
| Bourdeau, A | 1 |
| Hervé, MA | 1 |
| Hardin, JM | 1 |
| Fournier, A | 1 |
| Brennan, MF | 1 |
| Commerford, PJ | 1 |
| Lloyd, EA | 1 |
| Gugler, R | 1 |
| Musch, E | 1 |
| Mallory, A | 1 |
| Kern, F | 1 |
| Bilezikian, JP | 1 |
| Mallett, RB | 1 |
| Sainsbury, R | 1 |
| Benton, KG | 1 |
| Lanier, D | 1 |
| Favre, H | 1 |
| Jacob, AI | 1 |
| Bourgoignie, JJ | 1 |
| Sasaki, H | 1 |
| Miyake, K | 1 |
| Okumura, M | 1 |
| Eimoto, T | 1 |
| Glick, H | 1 |
| Minervini, D | 1 |
| Goldstone, RJ | 1 |
| Vellar, D | 1 |
| Henderson, M | 1 |
| Vellar, ID | 1 |
| Desmond, P | 1 |
| Sarosdy, MF | 1 |
| Saylor, R | 1 |
| Dittman, W | 1 |
| Cruz, AB | 1 |
| Gaskill, HV | 1 |
| Banowsky, LH | 1 |
5 reviews available for cimetidine and Milk-Alkali Syndrome
| Article | Year |
|---|---|
Primary hyperparathyroidism.
Topics: Adenoma; Aged; Cimetidine; Diphosphonates; Female; Humans; Hypercalcemia; Hyperparathyroidism; Male; | 1983 |
Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Cimetidine; Digitalis Glycoside | 1984 |
Drug-induced pancreatitis: a critical review.
Topics: Acetaminophen; Adrenal Cortex Hormones; Amphetamines; Asparaginase; Azathioprine; Chlorthalidone; Ch | 1980 |
The medical management of primary hyperparathyroidism.
Topics: Calcitonin; Calcium, Dietary; Cimetidine; Diphosphonates; Estrogens; Humans; Hypercalcemia; Hyperpar | 1982 |
Hyperparathyroid crisis reviewed: a role for parenteral cimetidine?
Topics: Adult; Aged; Calcium; Cimetidine; Emergencies; Female; Humans; Hypercalcemia; Hyperparathyroidism; M | 1986 |
10 other studies available for cimetidine and Milk-Alkali Syndrome
| Article | Year |
|---|---|
Effect of cimetidine on circulating parathyroid hormone in primary hyperparathyroidism.
Topics: Adenoma; Administration, Oral; Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperpar | 1980 |
Cimetidine and hyperparathyroidism.
Topics: Adult; Calcium; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Male; Mi | 1980 |
Cimetidine in primary hyperparathyroidism.
Topics: Cimetidine; Drug Evaluation; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Male | 1980 |
[Primary hyperparathyroidism. Lack of effect of cimetidine on plasma levels of parathyroid hormone and calcium].
Topics: Adolescent; Adult; Aged; Calcium; Child; Cimetidine; Female; Humans; Hypercalcemia; Hyperparathyroid | 1984 |
[Metabolic effects of antacids and interactions with other drugs].
Topics: Absorption; Alkalosis; Antacids; Cimetidine; Drug Interactions; Gastric Acid; Humans; Hypercalcemia; | 1983 |
Failure of cimetidine to suppress immunoreactive parathyroid hormone and hypercalcaemia in primary hyperparathyroidism.
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism; Parathyroid Hormon | 1981 |
Cimetidine therapy for severe hypercalcemia in two chronic hemodialysis patients.
Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; Middle | 1980 |
[Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism].
Topics: Adenoma; Aged; Alkaline Phosphatase; Cimetidine; Etidronic Acid; Humans; Hypercalcemia; Hyperparathy | 1988 |
The Zollinger-Ellison syndrome: a review of the St Vincent's Hospital, Melbourne experience.
Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Female; Gastric Acid; Humans; Hypercal | 1985 |
Upper gastrointestinal bleeding following renal transplantation.
Topics: Antacids; Blood Transfusion; Calcium; Cimetidine; Embolization, Therapeutic; Gastrointestinal Hemorr | 1985 |