cimetidine has been researched along with Middle Ear Effusion in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine, which has been found in middle ear effusions, is a potent pharmacological mediator released at an early stage of allergic reactions or general inflammatory process, increasing permeability of small blood vessels." | 7.68 | Histamine-induced mucociliary dysfunction and otitis media with effusion. ( Esaki, Y; Furuya, H; Nakai, Y; Ohashi, Y; Ohno, Y; Okamoto, H; Sugiura, Y, 1991) |
| "Histamine, which has been found in middle ear effusions, is a potent pharmacological mediator released at an early stage of allergic reactions or general inflammatory process, increasing permeability of small blood vessels." | 3.68 | Histamine-induced mucociliary dysfunction and otitis media with effusion. ( Esaki, Y; Furuya, H; Nakai, Y; Ohashi, Y; Ohno, Y; Okamoto, H; Sugiura, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, W | 1 |
| Jiang, H | 1 |
| Qiu, J | 1 |
| Esaki, Y | 1 |
| Ohashi, Y | 1 |
| Furuya, H | 1 |
| Sugiura, Y | 1 |
| Ohno, Y | 1 |
| Okamoto, H | 1 |
| Nakai, Y | 1 |
2 other studies available for cimetidine and Middle Ear Effusion
| Article | Year |
|---|---|
[The effect of substance P upon middle ear effusion of secretory otitis media and the mode of action].
Topics: Animals; Cats; Cimetidine; Ear, Middle; Histamine H2 Antagonists; Mucous Membrane; Otitis Media with | 1997 |
Histamine-induced mucociliary dysfunction and otitis media with effusion.
Topics: Animals; Cilia; Cimetidine; Diphenhydramine; Ear, Middle; Eustachian Tube; Guinea Pigs; Histamine; M | 1991 |