cimetidine has been researched along with Methemoglobinemia in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
Excerpt | Relevance | Reference |
---|---|---|
" We have attempted to reduce dapsone-dependent methaemoglobinaemia formation in six dermatitis herpetiformis patients stabilised on dapsone by the co-administration of cimetidine." | 7.68 | The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients. ( Breckenridge, AM; Coleman, MD; Friedmann, PS; Park, BK; Rhodes, LE; Scott, AK; Verbov, JL, 1992) |
" We have attempted to reduce dapsone-dependent methaemoglobinaemia formation in six dermatitis herpetiformis patients stabilised on dapsone by the co-administration of cimetidine." | 3.68 | The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients. ( Breckenridge, AM; Coleman, MD; Friedmann, PS; Park, BK; Rhodes, LE; Scott, AK; Verbov, JL, 1992) |
" Daily dosing of mice with dapsone (50 mg kg-1, p." | 1.29 | A dapsone-induced blood dyscrasia in the mouse: evidence for the role of an active metabolite. ( Ahmadi, M; Khalaf, LF; Nicholls, PJ; Smith, HJ, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 8 (88.89) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mehta, M | 1 |
Ahmadi, M | 1 |
Khalaf, LF | 1 |
Smith, HJ | 1 |
Nicholls, PJ | 1 |
Lu, HC | 1 |
Shih, RD | 1 |
Marcus, S | 1 |
Ruck, B | 1 |
Jennis, T | 1 |
Coleman, MD | 6 |
Russell, RM | 1 |
Tingle, MD | 2 |
Park, BK | 6 |
Rhodes, LE | 1 |
Scott, AK | 2 |
Verbov, JL | 1 |
Friedmann, PS | 1 |
Breckenridge, AM | 4 |
Hoaksey, PE | 1 |
Winn, MJ | 1 |
9 other studies available for cimetidine and Methemoglobinemia
Article | Year |
---|---|
Cimetidine and dapsone-mediated methaemoglobinaemia.
Topics: Anti-Infective Agents; Cimetidine; Dapsone; Histamine H2 Antagonists; Humans; Methemoglobinemia; Pos | 2007 |
A dapsone-induced blood dyscrasia in the mouse: evidence for the role of an active metabolite.
Topics: Animals; Cimetidine; Dapsone; Enzyme Inhibitors; Female; Folic Acid Antagonists; Histamine H2 Antago | 1996 |
Pseudomethemoglobinemia: a case report and review of sulfhemoglobinemia.
Topics: Acetaminophen; Adolescent; Cimetidine; Diagnosis, Differential; Female; Humans; Ibuprofen; Methemogl | 1998 |
Inhibition of dapsone-induced methaemoglobinaemia by cimetidine in the presence of trimethoprim in the rat.
Topics: Acetylation; Animals; Cimetidine; Dapsone; Drug Interactions; Half-Life; Male; Methemoglobin; Methem | 1992 |
The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients.
Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Dapsone; Dermatitis Herpetiformis; Drug Therapy, Combina | 1992 |
Inhibition of dapsone-induced methaemoglobinaemia by cimetidine in the rat during chronic dapsone administration.
Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Dapsone; Hydroxylation; Male; Methemoglob | 1991 |
Inhibition of dapsone-induced methaemoglobinaemia in the rat isolated perfused liver.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Cimetidine; Dapsone; Half-Life; Liver; Male; Me | 1990 |
The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man.
Topics: Adult; Cimetidine; Dapsone; Humans; Hydroxylation; Male; Methemoglobinemia | 1990 |
Inhibition of dapsone-induced methaemoglobinaemia in the rat.
Topics: Animals; Cimetidine; Dapsone; Male; Methemoglobinemia; Piperonyl Butoxide; Rats; Rats, Inbred Strain | 1990 |