cimetidine has been researched along with Mastocytosis in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Mastocytosis: A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with cimetidine (H2 receptor antagonist) resulted in diarrhea, however, the addition of cyproheptadine (H1 receptor antagonist) was beneficial in amelioration of the cutaneous symptoms of mastocytosis." | 3.68 | Systemic mastocytosis treated with histamine H1 and H2 receptor antagonists. ( Falk, ES; Gasior-Chrzan, B, 1992) |
| "In the cyclosporin-A- and prednisolone-treated groups, mastocytosis was suppressed, but worm expulsion was only slightly delayed, without statistical significance." | 1.32 | Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense. ( Chai, JY; Guk, SM; Hong, SJ; Kim, TH; Park, JH; Shin, EH, 2003) |
| " The dosage was increased to 975 mg every 6 hours, and he has had no further hypotensive episodes on this regime for 2 years." | 1.27 | Systemic mastocytosis: management of an unusual case with histamine (H1 and H2) antagonists and cyclooxygenase inhibition. ( Crawhall, JC; Wilkinson, RD, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shin, EH | 1 |
| Kim, TH | 1 |
| Hong, SJ | 1 |
| Park, JH | 1 |
| Guk, SM | 1 |
| Chai, JY | 1 |
| Gasior-Chrzan, B | 1 |
| Falk, ES | 1 |
| Crawhall, JC | 1 |
| Wilkinson, RD | 1 |
| Kawano, Y | 1 |
| Abe, H | 1 |
| Yoshida, K | 1 |
| Saitoh, F | 1 |
| Kuramochi, M | 1 |
| Ito, K | 1 |
| Omae, T | 1 |
| Jacoby, BG | 1 |
| Wesley, RE | 1 |
5 other studies available for cimetidine and Mastocytosis
| Article | Year |
|---|---|
Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense.
Topics: Animals; Cimetidine; Cyclosporine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; | 2003 |
Systemic mastocytosis treated with histamine H1 and H2 receptor antagonists.
Topics: Biopsy; Cimetidine; Colon; Cyproheptadine; Diarrhea; Drug Therapy, Combination; Humans; Liver; Male; | 1992 |
Systemic mastocytosis: management of an unusual case with histamine (H1 and H2) antagonists and cyclooxygenase inhibition.
Topics: Cimetidine; Cyclooxygenase Inhibitors; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; M | 1987 |
[A case of systemic mastocytosis with flushing, palpitation and dyspnea].
Topics: Chlorpheniramine; Cimetidine; Diagnosis, Differential; Drug Therapy, Combination; Dyspnea; Histamine | 1987 |
Painful orbital inflammatory lesions and mastocytosis.
Topics: Adolescent; Biopsy; Cimetidine; Clemastine; Combined Modality Therapy; Diphenhydramine; Drug Therapy | 1987 |