cimetidine has been researched along with Malabsorption Syndromes in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Malabsorption Syndromes: General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied." | 7.66 | Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. ( de Biéville, F; Fernandes, J; Kerrebijn, KF; Neijens, HJ; van Caillie, M, 1981) |
| "Ten patients (6 to 27 years of age) who had severe pancreatic exocrine insufficiency due to cystic fibrosis were studied to determine whether cimetidine would improve dietary fat and nitrogen absorption." | 7.66 | The effect of cimetidine on maldigestion in cystic fibrosis. ( Cox, KL; Dooley, RR; Isenberg, JN; Osher, AB, 1979) |
| "The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied." | 3.66 | Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. ( de Biéville, F; Fernandes, J; Kerrebijn, KF; Neijens, HJ; van Caillie, M, 1981) |
| "Ten patients (6 to 27 years of age) who had severe pancreatic exocrine insufficiency due to cystic fibrosis were studied to determine whether cimetidine would improve dietary fat and nitrogen absorption." | 3.66 | The effect of cimetidine on maldigestion in cystic fibrosis. ( Cox, KL; Dooley, RR; Isenberg, JN; Osher, AB, 1979) |
| " However, the patients' compliance is just as important; the dosage must be individualized." | 1.27 | Enzyme substitution in pancreatic disease. ( Andrén-Sandberg, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pounder, RE | 1 |
| Clark, JH | 1 |
| Modena, S | 1 |
| Crudo, V | 1 |
| Abrescia, F | 1 |
| Baratella, M | 1 |
| Bertrand, C | 1 |
| Salvagno, R | 1 |
| Vesentini, S | 1 |
| O'Laughlin, JC | 1 |
| Bredfeldt, JE | 1 |
| King, CE | 1 |
| Toskes, PP | 1 |
| de Biéville, F | 1 |
| Neijens, HJ | 1 |
| Fernandes, J | 1 |
| van Caillie, M | 1 |
| Kerrebijn, KF | 1 |
| Ansaldi, N | 1 |
| Auricchio, S | 1 |
| Cortot, A | 1 |
| Fleming, CR | 1 |
| Malagelada, JR | 2 |
| Murphy, JP | 2 |
| King, DR | 2 |
| Dubois, A | 2 |
| Cox, KL | 1 |
| Isenberg, JN | 1 |
| Osher, AB | 1 |
| Dooley, RR | 1 |
| Regan, PT | 1 |
| DiMagno, EP | 1 |
| Go, VL | 1 |
| Thompson, JS | 1 |
| Walan, A | 1 |
| Ström, M | 1 |
| Jacobsen, O | 1 |
| Ladefoged, K | 1 |
| Stage, JG | 1 |
| Jarnum, S | 1 |
| Goldman, CD | 1 |
| Rudloff, MA | 1 |
| Ternberg, JL | 1 |
| Andrén-Sandberg, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Proton Pump Inhibitors (PPI) and Fat Absorption in Subjects With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)[NCT03551691] | Phase 2 | 19 participants (Actual) | Interventional | 2018-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for cimetidine and Malabsorption Syndromes
| Article | Year |
|---|---|
Histamine H2-receptor antagonists and gastric acid secretion.
Topics: Burimamide; Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastric | 1984 |
Management of short bowel syndrome in the high-risk infant.
Topics: Adaptation, Physiological; Ambulatory Care; Child Development; Child, Preschool; Cimetidine; Growth; | 1984 |
[Nutrition problems in cystic fibrosis].
Topics: Caseins; Celiac Disease; Cimetidine; Cystic Fibrosis; Humans; Linoleic Acids; Malabsorption Syndrome | 1981 |
[Therapy of digestive insufficiency in cystic fibrosis].
Topics: Antacids; Bile Acids and Salts; Celiac Disease; Cimetidine; Cystic Fibrosis; Exocrine Pancreatic Ins | 1981 |
Drug-nutrient interactions: use of Cimetidine in malabsorption syndromes.
Topics: Celiac Disease; Cimetidine; Drug Synergism; Gastric Juice; Guanidines; Humans; Malabsorption Syndrom | 1978 |
Recent advances in the surgical treatment of the short-bowel syndrome.
Topics: Cimetidine; Humans; Malabsorption Syndromes; Parenteral Nutrition, Total; Short Bowel Syndrome | 1990 |
2 trials available for cimetidine and Malabsorption Syndromes
| Article | Year |
|---|---|
Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to pancreatic insufficiency.
Topics: Bicarbonates; Cimetidine; Drug Therapy, Combination; Guanidines; Humans; Malabsorption Syndromes; Pa | 1978 |
Effects of cimetidine on jejunostomy effluents in patients with severe short-bowel syndrome.
Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Female; Humans; Injections, Intravenous; Intestin | 1986 |
11 other studies available for cimetidine and Malabsorption Syndromes
| Article | Year |
|---|---|
[Esophago-gastro-enteric manifestations of scleroderma. Apropos of a clinical case].
Topics: Adult; Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Esophageal Diseases; Gastroesophageal Re | 1983 |
Treatment of systemic mastocytosis.
Topics: Cimetidine; Cromolyn Sodium; Guanidines; Humans; Malabsorption Syndromes; Urticaria Pigmentosa | 1980 |
Nutrient malabsorption in the Zollinger-Ellison syndrome. Normalization during long-term cimetidine therapy.
Topics: Cimetidine; Gastrectomy; Gastric Acid; Guanidines; Humans; Malabsorption Syndromes; Male; Middle Age | 1983 |
Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis.
Topics: Administration, Oral; Adolescent; Body Weight; Celiac Disease; Child; Cimetidine; Cystic Fibrosis; D | 1981 |
Improved nutrient absorption after cimetidine in short-bowel syndrome with gastric hypersecretion.
Topics: Adult; Cimetidine; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Digestion; Double-Blind Me | 1979 |
Effect of cimetidine on gastric acid secretion and fractional emptying in short bowel syndrome.
Topics: Cimetidine; Gastric Acid; Gastric Emptying; Humans; Malabsorption Syndromes; Short Bowel Syndrome | 1978 |
The effect of cimetidine on maldigestion in cystic fibrosis.
Topics: Adolescent; Adult; Celiac Disease; Child; Cimetidine; Cystic Fibrosis; Drug Therapy, Combination; Fe | 1979 |
Treatment of gastric hypersecretion with cimetidine in the short-bowel syndrome.
Topics: Cimetidine; Gastric Emptying; Gastric Juice; Gastrins; Guanidines; Humans; Intestinal Absorption; In | 1979 |
Metabolic consequences of reduced gastric acidity.
Topics: Antacids; Calcium; Cimetidine; Folic Acid; Gastric Acid; Histamine H2 Antagonists; Humans; Iron; Mal | 1985 |
Cimetidine and neonatal small bowel adaptation: an experimental study.
Topics: Adaptation, Physiological; Animals; Body Weight; Cimetidine; Ileum; Intestine, Small; Jejunum; Malab | 1987 |
Enzyme substitution in pancreatic disease.
Topics: Chronic Disease; Cimetidine; Exocrine Pancreatic Insufficiency; Humans; Malabsorption Syndromes; Pan | 1987 |