cimetidine has been researched along with Lymph Node Metastasis in 6 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "With the aim of potentiating the anti-tumour effect of interferon in metastatic malignant melanoma by concomitant inhibition of suppressor T cells, oral cimetidine (histamine-2 receptor antagonist) medication was added to interferon (HuIFN-alpha(Le] therapy in a series of 20 patients." | 7.66 | Metastatic malignant melanoma: regression induced by combined treatment with interferon [HuIFN-alpha(Le)] and cimetidine. ( Borgström, S; Flodgren, P; Jönsson, PE; Lindström, C; Sjögren, HO, 1983) |
| "With the aim of potentiating the anti-tumour effect of interferon in metastatic malignant melanoma by concomitant inhibition of suppressor T cells, oral cimetidine (histamine-2 receptor antagonist) medication was added to interferon (HuIFN-alpha(Le] therapy in a series of 20 patients." | 3.66 | Metastatic malignant melanoma: regression induced by combined treatment with interferon [HuIFN-alpha(Le)] and cimetidine. ( Borgström, S; Flodgren, P; Jönsson, PE; Lindström, C; Sjögren, HO, 1983) |
| "The prognosis of advanced renal cell carcinoma, especially with metastatic lesions was very poor." | 2.67 | [Management of advanced renal cell carcinoma: surgical treatment of metastasis]. ( Kinouchi, T; Kotake, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flodgren, P | 1 |
| Borgström, S | 1 |
| Jönsson, PE | 1 |
| Lindström, C | 1 |
| Sjögren, HO | 1 |
| Kinouchi, T | 2 |
| Kotake, T | 2 |
| Piura, B | 1 |
| Meirovitz, M | 1 |
| Kedar, I | 1 |
| Saiki, S | 1 |
| Kuroda, M | 1 |
| Miki, T | 1 |
| Kiyohara, H | 1 |
| Usami, M | 1 |
| Herrmann, R | 1 |
| Manegold, C | 1 |
| Maurer, B | 1 |
| Hennig, FW | 1 |
| Matthiessen, W | 1 |
| Norton, JA | 1 |
| Sugarbaker, PH | 1 |
| Doppman, JL | 1 |
| Wesley, RA | 1 |
| Maton, PN | 1 |
| Gardner, JD | 1 |
| Jensen, RT | 1 |
2 trials available for cimetidine and Lymph Node Metastasis
| Article | Year |
|---|---|
[Management of advanced renal cell carcinoma: surgical treatment of metastasis].
Topics: Adrenal Gland Neoplasms; Aged; Bone Neoplasms; Carcinoma, Renal Cell; Cimetidine; Combined Modality | 1994 |
Phase II trial of coumarin and cimetidine in advanced renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cel | 1990 |
4 other studies available for cimetidine and Lymph Node Metastasis
| Article | Year |
|---|---|
Metastatic malignant melanoma: regression induced by combined treatment with interferon [HuIFN-alpha(Le)] and cimetidine.
Topics: Adult; Aged; Cimetidine; Combined Modality Therapy; Female; Humans; Interferon Type I; Lung Neoplasm | 1983 |
Long-term disease-free survival following surgery and active specific immunotherapy with allogeneic vaccine in a patient with high-risk malignant melanoma of the vulva.
Topics: Adult; Cancer Vaccines; Cimetidine; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Sti | 1998 |
Treatment of metastatic renal cell carcinoma with a combination of human lymphoblastoid interferon-alpha and cimetidine.
Topics: Administration, Oral; Aged; Bone Neoplasms; Carcinoma, Renal Cell; Cimetidine; Female; Humans; Injec | 1991 |
Aggressive resection of metastatic disease in selected patients with malignant gastrinoma.
Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Combin | 1986 |