cimetidine has been researched along with Lupus Nephritis in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether short-term use of oral cimetidine improves the precision of creatinine clearance (CCr) and reduces the overestimation of glomerular filtration rate (GFR) that occurs with this test in patients with lupus nephritis (because creatinine is secreted by injured renal tubular cells)." | 9.06 | Oral cimetidine improves the accuracy and precision of creatinine clearance in lupus nephritis. ( Drew, H; Hellmann, DB; Moyer, M; Petri, M; Roubenoff, R; Whiting-O'Keefe, Q, 1990) |
| "To determine whether short-term use of oral cimetidine improves the precision of creatinine clearance (CCr) and reduces the overestimation of glomerular filtration rate (GFR) that occurs with this test in patients with lupus nephritis (because creatinine is secreted by injured renal tubular cells)." | 5.06 | Oral cimetidine improves the accuracy and precision of creatinine clearance in lupus nephritis. ( Drew, H; Hellmann, DB; Moyer, M; Petri, M; Roubenoff, R; Whiting-O'Keefe, Q, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roubenoff, R | 1 |
| Drew, H | 1 |
| Moyer, M | 1 |
| Petri, M | 1 |
| Whiting-O'Keefe, Q | 1 |
| Hellmann, DB | 1 |
1 trial available for cimetidine and Lupus Nephritis
| Article | Year |
|---|---|
Oral cimetidine improves the accuracy and precision of creatinine clearance in lupus nephritis.
Topics: Adult; Cimetidine; Confidence Intervals; Creatinine; Double-Blind Method; Female; Glomerular Filtrat | 1990 |