cimetidine has been researched along with Lung Adenocarcinoma in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We found that cimetidine treatment in a xenograft model using A549 lung adenocarcinoma cells resulted in decreased tumor volume compared to vehicle control; however, while the effect was in the same direction as the original study (Figure 4C; Sirota et al." | 3.85 | Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data. ( Aird, F; Kandela, I, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kandela, I | 2 |
| Zervantonakis, I | 1 |
| Aird, F | 1 |
2 other studies available for cimetidine and Lung Adenocarcinoma
| Article | Year |
|---|---|
Registered report: Discovery and preclinical validation of drug indications using compendia of public gene expression data.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antibiotics, Antineoplastic; Carcinoma, Renal Cell; | 2015 |
Replication Study: Discovery and preclinical validation of drug indications using compendia of public gene expression data.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Carcinoma, Renal Cell; Cimetidine; Data | 2017 |