cimetidine has been researched along with Long Sleeper Syndrome in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the clinical importance of this effect in 10 patients, who were receiving long-term treatment with diazepam for anxiety, tension, or difficulty in sleeping, in an eight-week double-blind controlled study during which the diazepam dosage remained constant." | 2.65 | Clinical importance of the interaction of diazepam and cimetidine. ( Abernethy, DR; Greenblatt, DJ; Harmatz, JS; Morse, DS; Shader, RI, 1984) |
| "Cimetidine can cause impairment of metabolism of the benzodiazepines by inhibiting the hepatic microsomal enzyme system and its possible role in causing the prolonged somnolence is discussed." | 1.26 | Cimetidine and prolonged post-operative somnolence. ( Lam, AM; Parkin, JA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenblatt, DJ | 1 |
| Abernethy, DR | 1 |
| Morse, DS | 1 |
| Harmatz, JS | 1 |
| Shader, RI | 1 |
| Lam, AM | 1 |
| Parkin, JA | 1 |
| Shepherd, RW | 1 |
| Wren, J | 1 |
| Evans, S | 1 |
| Lander, M | 1 |
| Ong, TH | 1 |
1 trial available for cimetidine and Long Sleeper Syndrome
| Article | Year |
|---|---|
Clinical importance of the interaction of diazepam and cimetidine.
Topics: Adult; Anxiety; Cimetidine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Interactio | 1984 |
2 other studies available for cimetidine and Long Sleeper Syndrome
| Article | Year |
|---|---|
Cimetidine and prolonged post-operative somnolence.
Topics: Aged; Cimetidine; Guanidines; Humans; Male; Oxazepam; Postoperative Complications; Sleep Wake Disord | 1981 |
Gastroesophageal reflux in children. Clinical profile, course and outcome with active therapy in 126 cases.
Topics: Child; Child, Preschool; Cimetidine; Endoscopy; Esophagitis, Peptic; Feeding Behavior; Female; Fiber | 1987 |