Page last updated: 2024-10-25

cimetidine and Long Sleeper Syndrome

cimetidine has been researched along with Long Sleeper Syndrome in 3 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
" We studied the clinical importance of this effect in 10 patients, who were receiving long-term treatment with diazepam for anxiety, tension, or difficulty in sleeping, in an eight-week double-blind controlled study during which the diazepam dosage remained constant."2.65Clinical importance of the interaction of diazepam and cimetidine. ( Abernethy, DR; Greenblatt, DJ; Harmatz, JS; Morse, DS; Shader, RI, 1984)
"Cimetidine can cause impairment of metabolism of the benzodiazepines by inhibiting the hepatic microsomal enzyme system and its possible role in causing the prolonged somnolence is discussed."1.26Cimetidine and prolonged post-operative somnolence. ( Lam, AM; Parkin, JA, 1981)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenblatt, DJ1
Abernethy, DR1
Morse, DS1
Harmatz, JS1
Shader, RI1
Lam, AM1
Parkin, JA1
Shepherd, RW1
Wren, J1
Evans, S1
Lander, M1
Ong, TH1

Trials

1 trial available for cimetidine and Long Sleeper Syndrome

ArticleYear
Clinical importance of the interaction of diazepam and cimetidine.
    The New England journal of medicine, 1984, Jun-21, Volume: 310, Issue:25

    Topics: Adult; Anxiety; Cimetidine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Interactio

1984

Other Studies

2 other studies available for cimetidine and Long Sleeper Syndrome

ArticleYear
Cimetidine and prolonged post-operative somnolence.
    Canadian Anaesthetists' Society journal, 1981, Volume: 28, Issue:5

    Topics: Aged; Cimetidine; Guanidines; Humans; Male; Oxazepam; Postoperative Complications; Sleep Wake Disord

1981
Gastroesophageal reflux in children. Clinical profile, course and outcome with active therapy in 126 cases.
    Clinical pediatrics, 1987, Volume: 26, Issue:2

    Topics: Child; Child, Preschool; Cimetidine; Endoscopy; Esophagitis, Peptic; Feeding Behavior; Female; Fiber

1987