cimetidine has been researched along with Long Sleeper Syndrome in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Excerpt | Relevance | Reference |
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" We studied the clinical importance of this effect in 10 patients, who were receiving long-term treatment with diazepam for anxiety, tension, or difficulty in sleeping, in an eight-week double-blind controlled study during which the diazepam dosage remained constant." | 2.65 | Clinical importance of the interaction of diazepam and cimetidine. ( Abernethy, DR; Greenblatt, DJ; Harmatz, JS; Morse, DS; Shader, RI, 1984) |
"Cimetidine can cause impairment of metabolism of the benzodiazepines by inhibiting the hepatic microsomal enzyme system and its possible role in causing the prolonged somnolence is discussed." | 1.26 | Cimetidine and prolonged post-operative somnolence. ( Lam, AM; Parkin, JA, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Greenblatt, DJ | 1 |
Abernethy, DR | 1 |
Morse, DS | 1 |
Harmatz, JS | 1 |
Shader, RI | 1 |
Lam, AM | 1 |
Parkin, JA | 1 |
Shepherd, RW | 1 |
Wren, J | 1 |
Evans, S | 1 |
Lander, M | 1 |
Ong, TH | 1 |
1 trial available for cimetidine and Long Sleeper Syndrome
Article | Year |
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Clinical importance of the interaction of diazepam and cimetidine.
Topics: Adult; Anxiety; Cimetidine; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Interactio | 1984 |
2 other studies available for cimetidine and Long Sleeper Syndrome
Article | Year |
---|---|
Cimetidine and prolonged post-operative somnolence.
Topics: Aged; Cimetidine; Guanidines; Humans; Male; Oxazepam; Postoperative Complications; Sleep Wake Disord | 1981 |
Gastroesophageal reflux in children. Clinical profile, course and outcome with active therapy in 126 cases.
Topics: Child; Child, Preschool; Cimetidine; Endoscopy; Esophagitis, Peptic; Feeding Behavior; Female; Fiber | 1987 |