cimetidine has been researched along with Leprosy in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the capacity of cimetidine to enhance cellular immunity in patients with lepromatous leprosy (LL), cimetidine was given for one month to 29 inactive LL patients and 3 active LL patients." | 9.05 | A study of the immunological effects of cimetidine in patients with lepromatous leprosy. ( Brown, AE; Bullock, WE; Makonkawkeyoon, S; Nelson, KE; Scollard, DM; Vithayasai, V, 1985) |
| "To test the capacity of cimetidine to enhance cellular immunity in patients with lepromatous leprosy (LL), cimetidine was given for one month to 29 inactive LL patients and 3 active LL patients." | 5.05 | A study of the immunological effects of cimetidine in patients with lepromatous leprosy. ( Brown, AE; Bullock, WE; Makonkawkeyoon, S; Nelson, KE; Scollard, DM; Vithayasai, V, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Converse, PJ | 1 |
| Mshana, RM | 1 |
| Bjune, GJ | 1 |
| Mathur, NK | 1 |
| Bumb, RA | 1 |
| Mathur, DC | 1 |
| Jain, SK | 1 |
| Brown, AE | 1 |
| Nelson, KE | 1 |
| Makonkawkeyoon, S | 1 |
| Vithayasai, V | 1 |
| Scollard, DM | 1 |
| Bullock, WE | 1 |
1 trial available for cimetidine and Leprosy
| Article | Year |
|---|---|
A study of the immunological effects of cimetidine in patients with lepromatous leprosy.
Topics: Adjuvants, Immunologic; Adult; BCG Vaccine; Cimetidine; Clinical Trials as Topic; Double-Blind Metho | 1985 |
2 other studies available for cimetidine and Leprosy
| Article | Year |
|---|---|
Cimetidine inhibits suppressor factor production in Ethiopian lepromatous leprosy patients.
Topics: Cimetidine; Ethiopia; Humans; Immune Tolerance; Immunity, Cellular; Leprosy; Lymphocyte Activation; | 1987 |
Trial of cimetidine in lepromatous leprosy--a futile attempt.
Topics: Cimetidine; Humans; Leprosy | 1986 |