cimetidine has been researched along with Invasiveness, Neoplasm in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current use of H(2) blockers overall, cimetidine, and famotidine was not associated with an increased risk of either invasive ductal or invasive lobular breast cancer." | 3.74 | Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer. ( Daling, JR; Li, CI; Malone, KE; Mathes, RW; Porter, PL, 2008) |
| "Human gastric cancer cells of the line SGC-790 were cultured." | 1.33 | [Effects of cimetidine on the biological behaviors of human gastric cancer cells]. ( Gao, J; Jiang, CG; Liu, FR; Wu, T; Xu, HM, 2006) |
| "Colon cancer was induced in 40 Sprague Dawley rats using a 10-week course of 1,2 dimethylhydrazine (DMH)." | 1.29 | The growth of carcinogen-induced colon cancer in rats is inhibited by cimetidine. ( Adams, WJ; Cook, TA; Lawson, JA; Morris, DL; Nicholson, SE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuda, M | 1 |
| Kusama, K | 1 |
| Sakashita, H | 1 |
| Tozawa, K | 1 |
| Okamoto, T | 1 |
| Kawai, N | 1 |
| Hashimoto, Y | 1 |
| Hayashi, Y | 1 |
| Kohri, K | 1 |
| Jiang, CG | 1 |
| Liu, FR | 1 |
| Xu, HM | 1 |
| Wu, T | 1 |
| Gao, J | 1 |
| Mathes, RW | 1 |
| Malone, KE | 1 |
| Daling, JR | 1 |
| Porter, PL | 1 |
| Li, CI | 1 |
| Adams, WJ | 1 |
| Lawson, JA | 1 |
| Nicholson, SE | 1 |
| Cook, TA | 1 |
| Morris, DL | 1 |
5 other studies available for cimetidine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression.
Topics: Animals; Apoptosis; Cell Adhesion; Cimetidine; Dose-Response Relationship, Drug; Down-Regulation; Ge | 2008 |
Positive correlation between sialyl Lewis X expression and pathologic findings in renal cell carcinoma.
Topics: Adjuvants, Immunologic; Carcinoma, Renal Cell; Cimetidine; Humans; Immunohistochemistry; Kidney Neop | 2005 |
[Effects of cimetidine on the biological behaviors of human gastric cancer cells].
Topics: Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cimetidine; Extracellular Matrix; Hu | 2006 |
Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer.
Topics: Aged; Anti-Ulcer Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Case-Contr | 2008 |
The growth of carcinogen-induced colon cancer in rats is inhibited by cimetidine.
Topics: 1,2-Dimethylhydrazine; Animals; Antigens, Neoplasm; Carcinogens; Cell Division; Chi-Square Distribut | 1993 |