cimetidine has been researched along with Intraocular Pressure in 8 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of an intravenous infusion of cimetidine, 2 mg/kg of body weight over 1 hour, on intraocular pressure was studied in four patients with medically controlled glaucoma and compared with the effect of a control infusion of normal saline." | 7.67 | Effect of cimetidine on intraocular pressure in patients with glaucoma. ( Clark, L; Cohen, MM; Feldman, F; Hudy, D, 1984) |
| "The effect of an intravenous infusion of cimetidine (2 mg/kg of body weight/hr) on intraocular pressure and gastric acid secretion was determined in four healthy young adults and compared with the effect of a control infusion of normal saline." | 7.66 | Effect of histamine-2 receptor blockade by cimetidine on intraocular pressure in humans. ( Cohen, MM; Feldman, F, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feldman, F | 2 |
| Cohen, MM | 2 |
| Dobrilla, G | 1 |
| Felder, M | 1 |
| Chilovi, F | 1 |
| de Pretis, G | 1 |
| García Plaza, A | 1 |
| Pascasio Acevedo, JM | 1 |
| Clark, L | 1 |
| Hudy, D | 1 |
| Ishii, Y | 1 |
| Nakamura, K | 1 |
| Tsutsumi, K | 1 |
| Kotegawa, T | 1 |
| Nakano, S | 1 |
| Nakatsuka, K | 1 |
| Trzeciakowski, JP | 1 |
| Frye, GD | 1 |
| Mindel, JS | 1 |
| Friedman, AH | 1 |
| Haimov, T | 1 |
| Kharlamb, AB | 1 |
| Freilich, JM | 1 |
| Mukherji, R | 1 |
| Sengupta, KK | 1 |
| Bhattacharya, A | 1 |
1 review available for cimetidine and Intraocular Pressure
| Article | Year |
|---|---|
[Review of histamine H2 receptor antagonists].
Topics: Animals; Anti-Ulcer Agents; Central Nervous System; Cimetidine; Drug Interactions; Endocrine System | 1984 |
2 trials available for cimetidine and Intraocular Pressure
| Article | Year |
|---|---|
Exacerbation of glaucoma associated with both cimetidine and ranitidine.
Topics: Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Furans; Glaucoma; Guanidines; Humans; Intraocu | 1982 |
Drug interaction between cimetidine and timolol ophthalmic solution: effect on heart rate and intraocular pressure in healthy Japanese volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Cimetidine; Cytochrome P-450 CYP2D6 Inhibitors; Double-Blind Met | 2000 |
5 other studies available for cimetidine and Intraocular Pressure
| Article | Year |
|---|---|
Effect of histamine-2 receptor blockade by cimetidine on intraocular pressure in humans.
Topics: Adult; Cimetidine; Female; Gastric Acid; Gastric Juice; Guanidines; Histamine H2 Antagonists; Humans | 1982 |
Effect of cimetidine on intraocular pressure in patients with glaucoma.
Topics: Adult; Cimetidine; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged | 1984 |
Effects of intraventricular histamine and H2 receptor antagonists on intraocular pressure.
Topics: Animals; Cerebral Ventricles; Cimetidine; Female; Histamine; Histamine H2 Antagonists; Injections, I | 1987 |
Eosinophil chemotaxis and anterior uveitis from topical dimaprit and nordimaprit.
Topics: Animals; Chemotaxis, Leukocyte; Cimetidine; Dimaprit; Eosinophils; Eye Color; Intraocular Pressure; | 1986 |
Effect of histamine H2-receptor antagonist (cimetidine) on intra-ocular pressure.
Topics: Adult; Cimetidine; Female; Humans; Intraocular Pressure; Male; Middle Aged | 1988 |