cimetidine has been researched along with Injury, Myocardial Reperfusion in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Surprisingly, the incidences of ischaemia- and reperfusion-induced arrhythmias were not reduced by ranitidine over an equivalent concentration range (0." | 3.69 | Protection by cimetidine, but not ranitidine, implies that H2 receptors do not mediate arrhythmogenesis in a rat model of regional ischaemia and reperfusion in vitro. ( Banning, MM; Curtis, MJ, 1995) |
| "The effects of cimetidine (Cim) on ventricular fibrillation threshold (VFT), diastolic excitation threshold (DET), effective refractory period (ERP), and vulnerable period (VP), were determined in both stable perfusion and postischemic reperfusion rat hearts." | 3.68 | Effect of cimetidine on isolated rat myocardial reperfusion injury. ( Hu, HC; Wu, S; Xu, XZ, 1992) |
| "Chloramphenicol is an inhibitor of mitochondrial protein synthesis and is also an inhibitor of a subset of cytochrome P450 monooxygenases (CYPs)." | 1.32 | Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. ( Gottlieb, RA; Granville, DJ; Gustafsson, AB; Huang, C; Sayen, MR; Takeuchi, C; Tashakkor, B; Wentworth, P; Yeager, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishihara, Y | 1 |
| Sekine, M | 1 |
| Nakazawa, M | 1 |
| Shimamoto, N | 1 |
| Granville, DJ | 1 |
| Tashakkor, B | 1 |
| Takeuchi, C | 1 |
| Gustafsson, AB | 1 |
| Huang, C | 1 |
| Sayen, MR | 1 |
| Wentworth, P | 1 |
| Yeager, M | 1 |
| Gottlieb, RA | 1 |
| Banning, MM | 1 |
| Curtis, MJ | 1 |
| Dzierzkowska, J | 1 |
| Witanowska, A | 1 |
| Ciurzynska, G | 1 |
| Chciuk-Górnicka, M | 1 |
| Jozwicka, M | 1 |
| Gajewski, M | 1 |
| Kurenko-Deptuch, M | 1 |
| Deptuch, TW | 1 |
| Maslinski, S | 1 |
| Wu, S | 1 |
| Hu, HC | 1 |
| Xu, XZ | 1 |
5 other studies available for cimetidine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Suppression of myocardial ischemia-reperfusion injury by inhibitors of cytochrome P450 in rats.
Topics: Animals; Body Weight; Cimetidine; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhib | 2009 |
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.
Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom | 2004 |
Protection by cimetidine, but not ranitidine, implies that H2 receptors do not mediate arrhythmogenesis in a rat model of regional ischaemia and reperfusion in vitro.
Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Dose-Response Relationship, Drug; Electrocardiography; Hi | 1995 |
The influence of intestinal ischaemia on energy balance in the myocardium during ischaemia-reperfusion induced cardiac injury in the rat.
Topics: Adenosine Triphosphate; Animals; Cimetidine; Energy Metabolism; Histamine H2 Antagonists; Intestines | 1999 |
Effect of cimetidine on isolated rat myocardial reperfusion injury.
Topics: Animals; Cimetidine; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred St | 1992 |