cimetidine has been researched along with Inflammation in 24 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine (CIM) is an H2-receptor antagonist that has been used in racehorses in an attempt to reduce the occurrence of stress-related gastric ulceration." | 5.30 | Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse. ( Dees, AA; Hunter, RP; Keowen, ML; Koch, CE; McClure, JR; Short, CR; VanSteenhouse, JL, 1999) |
| "Our recent in vitro studies on airways smooth muscles of the cat with turpentine oil inflammation showed the occurrence of a contractile response of tracheal preparations and a significant increase in the isometric tension of lung strips to histamine application." | 3.67 | Pharmacological analysis of reactivity changes in airways due to acute inflammation in cats. ( Bánovcin, P; Korpás, J; Visnovský, P, 1987) |
| "The histamine-induced increase in the content of VEGF protein in the conditioned medium was inhibited by the cyclic AMP antagonist Rp-cAMP (IC(50) 6." | 1.31 | Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. ( Ghosh, AK; Hirasawa, N; Ohuchi, K, 2001) |
| "These data support the view that hyperalgesia induced by the magnesium-depleted diet is not a consequence of the inflammatory process." | 1.31 | Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats. ( Alloui, A; Begon, S; Dubray, C; Eschalier, A; Mazur, A; Rayssiguier, Y, 2002) |
| "Cimetidine (CIM) is an H2-receptor antagonist that has been used in racehorses in an attempt to reduce the occurrence of stress-related gastric ulceration." | 1.30 | Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse. ( Dees, AA; Hunter, RP; Keowen, ML; Koch, CE; McClure, JR; Short, CR; VanSteenhouse, JL, 1999) |
| "Cimetidine was found to have no effect on the histological features of chronic/acute inflammation and erosion." | 1.27 | Histological findings in erosive prepyloric changes. ( Berstad, A; Nesland, AA; Serck-Hanssen, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (50.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Oprişoreanu, AM | 1 |
| Ryan, F | 1 |
| Richmond, C | 1 |
| Dzekhtsiarova, Y | 1 |
| Carragher, NO | 1 |
| Becker, T | 1 |
| David, S | 1 |
| Becker, CG | 1 |
| Boia-Ferreira, M | 1 |
| Moreno, KG | 1 |
| Basílio, ABC | 1 |
| da Silva, LP | 1 |
| Vuitika, L | 1 |
| Soley, B | 1 |
| Wille, ACM | 1 |
| Donatti, L | 1 |
| Barbaro, KC | 1 |
| Chaim, OM | 1 |
| Gremski, LH | 1 |
| Veiga, SS | 1 |
| Senff-Ribeiro, A | 1 |
| Baek, JS | 1 |
| Yeo, EW | 1 |
| Lee, YH | 1 |
| Tan, NS | 1 |
| Loo, SCJ | 1 |
| Arae, K | 1 |
| Oboki, K | 1 |
| Ohno, T | 1 |
| Hirata, M | 1 |
| Nakae, S | 1 |
| Taguchi, H | 1 |
| Saito, H | 1 |
| Nakajima, T | 1 |
| Liu, T | 1 |
| Bai, ZT | 1 |
| Pang, XY | 1 |
| Chai, ZF | 1 |
| Jiang, F | 1 |
| Ji, YH | 1 |
| Owen, DA | 2 |
| Poy, E | 1 |
| Woodward, DF | 2 |
| Daniel, D | 1 |
| Pipkin, MA | 1 |
| Raval, P | 1 |
| Lundberg, C | 1 |
| Gerdin, B | 1 |
| Witter, FR | 1 |
| King, TM | 1 |
| Blake, DA | 1 |
| Sperk, G | 1 |
| Ratzenhofer, E | 1 |
| Simbruner, G | 1 |
| Coradello, H | 1 |
| Pollak, A | 1 |
| Lubec, G | 1 |
| Germonpré, PR | 1 |
| Joos, GF | 1 |
| Everaert, E | 1 |
| Kips, JC | 1 |
| Pauwels, RA | 1 |
| Desouza, IA | 1 |
| Ribeiro-DaSilva, G | 1 |
| Hunter, RP | 1 |
| Short, CR | 1 |
| McClure, JR | 1 |
| Koch, CE | 1 |
| Keowen, ML | 1 |
| VanSteenhouse, JL | 1 |
| Dees, AA | 1 |
| Ghosh, AK | 1 |
| Hirasawa, N | 2 |
| Ohuchi, K | 1 |
| Begon, S | 1 |
| Alloui, A | 1 |
| Eschalier, A | 1 |
| Mazur, A | 1 |
| Rayssiguier, Y | 1 |
| Dubray, C | 1 |
| Fischer, SM | 1 |
| Patrick, KE | 1 |
| Patamalai, B | 1 |
| Slaga, TJ | 1 |
| Fantozzi, R | 2 |
| Brunelleschi, S | 1 |
| Giuliattini, L | 1 |
| Blandina, P | 1 |
| Masini, E | 2 |
| Cavallo, G | 1 |
| Mannaioni, PF | 2 |
| Giannella, E | 1 |
| Tsurufuji, S | 1 |
| Kamo, I | 1 |
| Hambleton, P | 1 |
| Miller, P | 1 |
| Evans, TW | 1 |
| Rogers, DF | 1 |
| Aursudkij, B | 1 |
| Chung, KF | 1 |
| Barnes, PJ | 1 |
| Bánovcin, P | 1 |
| Visnovský, P | 1 |
| Korpás, J | 1 |
| Nesland, AA | 1 |
| Berstad, A | 1 |
| Serck-Hanssen, A | 1 |
1 review available for cimetidine and Inflammation
| Article | Year |
|---|---|
The effects of chronic gastrointestinal medication on the fetus and neonate.
Topics: Abnormalities, Drug-Induced; Antacids; Antiemetics; Cathartics; Cimetidine; Colonic Diseases, Functi | 1981 |
23 other studies available for cimetidine and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Drug screening in zebrafish larvae reveals inflammation-related modulators of secondary damage after spinal cord injury in mice.
Topics: Animals; Cimetidine; Cytokines; Drug Evaluation, Preclinical; Inflammation; Larva; Mammals; Mice; Sp | 2023 |
TCTP from
Topics: Animals; Biomarkers, Tumor; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Hypersens | 2019 |
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Celecoxib; Cimetidine; Delayed-Action Preparation | 2017 |
Cimetidine enhances antigen-specific IgE and Th2 cytokine production.
Topics: Animals; Cells, Cultured; Cimetidine; Cytokines; Epitopes; Histamine H2 Antagonists; Hypersensitivit | 2011 |
Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom.
Topics: Animals; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Edema; Histamine Antagonist | 2007 |
Evaluation of the role of Histamine H1- and H2-receptors in cutaneous inflammation in the guinea-pig produced by histamine and mast cell degranulation.
Topics: Animals; Cimetidine; Dimaprit; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonis | 1980 |
Effect of histamine H1- and H2-receptor antagonists, steroidal and non-steroidal anti-inflammatory agents on carrageenin-induced inflammation of the guinea-pig ear.
Topics: Animals; Anti-Inflammatory Agents; Body Temperature; Carrageenan; Cimetidine; Ear; Glucocorticoids; | 1982 |
The role of histamine and serotonin in the inflammatory reaction in an experimental model of open wounds in the rat.
Topics: Animals; Capillary Permeability; Cimetidine; Granulation Tissue; Histamine; Histamine Antagonists; I | 1984 |
Evidence of H2 receptor activity on glomerular cells.
Topics: Animals; Binding Sites; Cimetidine; Histamine; In Vitro Techniques; Inflammation; Kidney Diseases; K | 1980 |
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Colorin | 1995 |
The pharmacological profile of mouse hind paw inflammation induced by staphylococcal enterotoxin type A.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Capsaicin; Cimetidi | 1997 |
Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse.
Topics: Animals; Anti-Ulcer Agents; Blood Proteins; Carrageenan; Chromatography, High Pressure Liquid; Cimet | 1999 |
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic A | 2001 |
Assessment of the relationship between hyperalgesia and peripheral inflammation in magnesium-deficient rats.
Topics: Animals; Anti-Inflammatory Agents; Astemizole; Cimetidine; Cromolyn Sodium; Dexamethasone; Disease M | 2002 |
Effects of antihistamines on phorbol ester tumor promotion and vascular permeability changes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Fema | 1990 |
Mast cell and neutrophil interactions: a role for superoxide anion and histamine.
Topics: Animals; Cimetidine; Histamine; Histamine Release; Humans; Inflammation; Male; Mast Cells; N-Formylm | 1985 |
Pathophysiological significance of the distribution of histamine receptor sub-types: a proposed dual role for histamine in inflammation and type I hypersensitivity reactions.
Topics: Animals; Cimetidine; Female; Guinea Pigs; Histamine; Humans; Hypersensitivity; In Vitro Techniques; | 1988 |
Analysis of the effects of cyclooxygenase and lipoxygenase inhibitors on leukocyte accumulation in the inflammatory site.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Cimetidine; Cyclooxygenase Inhibito | 1989 |
Pharmacological investigation of acute cellular accumulation in immunological air pouch inflammation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Aprotinin; Bromelai | 1989 |
Inflammatory mediators involved in antigen-induced airway microvascular leakage in guinea pigs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Bronchi; Capillary | 1988 |
Pharmacological analysis of reactivity changes in airways due to acute inflammation in cats.
Topics: Airway Resistance; Animals; Cats; Cimetidine; Female; Histamine; Histamine Antagonists; In Vitro Tec | 1987 |
Histological findings in erosive prepyloric changes.
Topics: Biopsy; Cimetidine; Dyspepsia; Endoscopy; Gastric Mucosa; Humans; Inflammation; Pylorus | 1986 |