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cimetidine and Infection, Postoperative Wound

cimetidine has been researched along with Infection, Postoperative Wound in 7 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study."9.05[Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984)
"The cimetidine treated patients had more abdominal infectious complications postoperatively but this difference only reached statistical significance when patients who were operated upon for bleeding were excluded."6.65Does preoperative treatment with cimetidine increase the risk of postoperative infection? ( Lundell, L; Persson, G, 1983)
"12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study."5.05[Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984)
"We examined the effect of cimetidine in altering gastric microflora in patients undergoing gastric resection for peptic ulcer disease."5.05The effect of antisecretagogues on gastric microflora. ( DeSantis, S; Klein, SR; Long, J; State, D; White, RA, 1983)
"The results of preoperative treatment of uncomplicated duodenal ulcer patients with Cimetidine are presented."3.67The effect of preoperative treatment with cimetidine on postoperative wound sepsis. ( Apostolidis, NS; Basioukas, PS; Calaitzopoulos, JD; Contostolis, SB; Contou, CT; Feretis, CB; Nissiotis, AS; Papoutsis, GG, 1984)
"The gastric microflora of patients receiving cimetidine for duodenal ulceration has been investigated and the results compared with those from a group of untreated patients."3.66Cimetidine and the potential risk of postoperative sepsis. ( Burdon, DW; Keighley, MR; Muscroft, TJ; Youngs, D, 1981)
"The cimetidine treated patients had more abdominal infectious complications postoperatively but this difference only reached statistical significance when patients who were operated upon for bleeding were excluded."2.65Does preoperative treatment with cimetidine increase the risk of postoperative infection? ( Lundell, L; Persson, G, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ketterl, R1
Hölscher, AH1
Weiser, HF1
Siewert, JR1
Feretis, CB1
Contou, CT1
Papoutsis, GG1
Contostolis, SB1
Basioukas, PS1
Calaitzopoulos, JD1
Nissiotis, AS1
Apostolidis, NS1
Lundell, L1
Persson, G1
Long, J1
DeSantis, S1
State, D1
White, RA1
Klein, SR1
Polk, HC1
Brown, GL1
Muscroft, TJ1
Youngs, D1
Burdon, DW1
Keighley, MR1
Katoh, J1
Tsuchiya, K1
Osawa, H1
Sato, W1
Matsumura, G1
Iida, Y1
Suzuki, S1
Hosaka, S1
Yoshii, S1
Tada, Y1

Trials

4 trials available for cimetidine and Infection, Postoperative Wound

ArticleYear
[Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study].
    Zeitschrift fur Gastroenterologie, 1984, Volume: 22, Issue:10

    Topics: Abscess; Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Critical Care; Double-Blind

1984
Does preoperative treatment with cimetidine increase the risk of postoperative infection?
    Annales chirurgiae et gynaecologiae, 1983, Volume: 72, Issue:6

    Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Con

1983
The effect of antisecretagogues on gastric microflora.
    Archives of surgery (Chicago, Ill. : 1960), 1983, Volume: 118, Issue:12

    Topics: Bacteria; Cimetidine; Gastric Acid; Humans; Hydrogen-Ion Concentration; Peptic Ulcer; Preoperative C

1983
Cimetidine reduces impairment of cellular immunity after cardiac operations with cardiopulmonary bypass.
    The Journal of thoracic and cardiovascular surgery, 1998, Volume: 116, Issue:2

    Topics: Antigens, CD; Cardiac Surgical Procedures; Cardiopulmonary Bypass; CD4-CD8 Ratio; Cimetidine; Female

1998

Other Studies

3 other studies available for cimetidine and Infection, Postoperative Wound

ArticleYear
The effect of preoperative treatment with cimetidine on postoperative wound sepsis.
    The American surgeon, 1984, Volume: 50, Issue:11

    Topics: Adult; Cimetidine; Duodenal Ulcer; Female; Gastric Acid; Humans; Male; Middle Aged; Preoperative Car

1984
The role of cimetidine in promoting infection after gastric surgery: primary or secondary effect?
    Annales chirurgiae et gynaecologiae, 1983, Volume: 72, Issue:6

    Topics: Cimetidine; Humans; Stomach; Surgical Wound Infection

1983
Cimetidine and the potential risk of postoperative sepsis.
    The British journal of surgery, 1981, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Aged; Bacteria; Cimetidine; Duodenal Ulcer; Female; Guanidines; Humans; Hydrogen-

1981