cimetidine has been researched along with Infection, Postoperative Wound in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study." | 9.05 | [Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984) |
| "The cimetidine treated patients had more abdominal infectious complications postoperatively but this difference only reached statistical significance when patients who were operated upon for bleeding were excluded." | 6.65 | Does preoperative treatment with cimetidine increase the risk of postoperative infection? ( Lundell, L; Persson, G, 1983) |
| "12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study." | 5.05 | [Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984) |
| "We examined the effect of cimetidine in altering gastric microflora in patients undergoing gastric resection for peptic ulcer disease." | 5.05 | The effect of antisecretagogues on gastric microflora. ( DeSantis, S; Klein, SR; Long, J; State, D; White, RA, 1983) |
| "The results of preoperative treatment of uncomplicated duodenal ulcer patients with Cimetidine are presented." | 3.67 | The effect of preoperative treatment with cimetidine on postoperative wound sepsis. ( Apostolidis, NS; Basioukas, PS; Calaitzopoulos, JD; Contostolis, SB; Contou, CT; Feretis, CB; Nissiotis, AS; Papoutsis, GG, 1984) |
| "The gastric microflora of patients receiving cimetidine for duodenal ulceration has been investigated and the results compared with those from a group of untreated patients." | 3.66 | Cimetidine and the potential risk of postoperative sepsis. ( Burdon, DW; Keighley, MR; Muscroft, TJ; Youngs, D, 1981) |
| "The cimetidine treated patients had more abdominal infectious complications postoperatively but this difference only reached statistical significance when patients who were operated upon for bleeding were excluded." | 2.65 | Does preoperative treatment with cimetidine increase the risk of postoperative infection? ( Lundell, L; Persson, G, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ketterl, R | 1 |
| Hölscher, AH | 1 |
| Weiser, HF | 1 |
| Siewert, JR | 1 |
| Feretis, CB | 1 |
| Contou, CT | 1 |
| Papoutsis, GG | 1 |
| Contostolis, SB | 1 |
| Basioukas, PS | 1 |
| Calaitzopoulos, JD | 1 |
| Nissiotis, AS | 1 |
| Apostolidis, NS | 1 |
| Lundell, L | 1 |
| Persson, G | 1 |
| Long, J | 1 |
| DeSantis, S | 1 |
| State, D | 1 |
| White, RA | 1 |
| Klein, SR | 1 |
| Polk, HC | 1 |
| Brown, GL | 1 |
| Muscroft, TJ | 1 |
| Youngs, D | 1 |
| Burdon, DW | 1 |
| Keighley, MR | 1 |
| Katoh, J | 1 |
| Tsuchiya, K | 1 |
| Osawa, H | 1 |
| Sato, W | 1 |
| Matsumura, G | 1 |
| Iida, Y | 1 |
| Suzuki, S | 1 |
| Hosaka, S | 1 |
| Yoshii, S | 1 |
| Tada, Y | 1 |
4 trials available for cimetidine and Infection, Postoperative Wound
| Article | Year |
|---|---|
[Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study].
Topics: Abscess; Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Critical Care; Double-Blind | 1984 |
Does preoperative treatment with cimetidine increase the risk of postoperative infection?
Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Con | 1983 |
The effect of antisecretagogues on gastric microflora.
Topics: Bacteria; Cimetidine; Gastric Acid; Humans; Hydrogen-Ion Concentration; Peptic Ulcer; Preoperative C | 1983 |
Cimetidine reduces impairment of cellular immunity after cardiac operations with cardiopulmonary bypass.
Topics: Antigens, CD; Cardiac Surgical Procedures; Cardiopulmonary Bypass; CD4-CD8 Ratio; Cimetidine; Female | 1998 |
3 other studies available for cimetidine and Infection, Postoperative Wound
| Article | Year |
|---|---|
The effect of preoperative treatment with cimetidine on postoperative wound sepsis.
Topics: Adult; Cimetidine; Duodenal Ulcer; Female; Gastric Acid; Humans; Male; Middle Aged; Preoperative Car | 1984 |
The role of cimetidine in promoting infection after gastric surgery: primary or secondary effect?
Topics: Cimetidine; Humans; Stomach; Surgical Wound Infection | 1983 |
Cimetidine and the potential risk of postoperative sepsis.
Topics: Adolescent; Adult; Aged; Bacteria; Cimetidine; Duodenal Ulcer; Female; Guanidines; Humans; Hydrogen- | 1981 |