cimetidine has been researched along with Impotence in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 8.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 4.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| " e) The gynaecomastia, galactorrhoea, amenorrhoea and impotence--reported only after long-term cimetidine treatment--can probably be attributed to the specific antiandrogen receptor property of CMT." | 4.77 | [Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations]. ( Biagi, P; Milani, G, 1985) |
| " Cimetidine used in the ulcer therapy shows a certain antiandrogenic effect and after a longer time may evoke impotence and other undesirable andrological side-effects which we, however, did not realize in 4 weeks treatment periods." | 3.66 | [Andrologic anomalies in various gastrointestinal diseases]. ( Szarvas, F, 1983) |
| " The scheme successfully detected and quantified some already known adverse effects of cimetidine and did not detect any new effects." | 1.27 | Post-marketing surveillance of the safety of cimetidine: twelve-month morbidity report. ( Colin Jones, DG; Langman, MJ; Lawson, DH; Vessey, MP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beeley, L | 1 |
| Jensen, RT | 2 |
| Collen, MJ | 2 |
| McArthur, KE | 1 |
| Howard, JM | 1 |
| Maton, PN | 1 |
| Cherner, JA | 1 |
| Gardner, JD | 2 |
| Reed, M | 1 |
| Strum, WB | 1 |
| Szarvas, F | 1 |
| Pandol, SJ | 1 |
| Allende, HD | 1 |
| Raufman, JP | 1 |
| Bissonnette, BM | 1 |
| Duncan, WC | 1 |
| Durgin, PL | 1 |
| Gillin, JC | 1 |
| Weideman, CL | 1 |
| Northcutt, RC | 1 |
| Peden, NR | 1 |
| Cargill, JM | 1 |
| Browning, MC | 1 |
| Saunders, JH | 1 |
| Wormsley, KG | 1 |
| Barber, SG | 1 |
| Adaikan, PG | 1 |
| Karim, SM | 1 |
| Wolfe, MM | 1 |
| Barth, JA | 1 |
| Gwee, MC | 1 |
| Cheah, LS | 1 |
| Estrada Rodríguez, M | 1 |
| Izquierdo de la Rosa, H | 1 |
| González Peláez, J | 1 |
| Arredondo Bruce, A | 1 |
| Jauhari, J | 1 |
| Niv, Y | 1 |
| Long, JP | 1 |
| Smyth, PP | 1 |
| Culliton, M | 1 |
| Cunningham, S | 1 |
| O'Donoghue, DP | 1 |
| Fitzgerald, O | 1 |
| McKenna, TJ | 1 |
| Biagi, P | 1 |
| Milani, G | 1 |
| Colin Jones, DG | 1 |
| Langman, MJ | 1 |
| Lawson, DH | 1 |
| Vessey, MP | 1 |
3 reviews available for cimetidine and Impotence
| Article | Year |
|---|---|
Drug-induced sexual dysfunction and infertility.
Topics: Adult; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzothiadiazines; Child; Cimetidine; | 1984 |
Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia.
Topics: Anesthesia; Animals; Antihypertensive Agents; Bradycardia; Cholinesterase Inhibitors; Cimetidine; Co | 1986 |
[Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations].
Topics: Amenorrhea; Androgens; Cimetidine; Erectile Dysfunction; Female; Follicle Stimulating Hormone; Galac | 1985 |
1 trial available for cimetidine and Impotence
| Article | Year |
|---|---|
Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states.
Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, C | 1984 |
15 other studies available for cimetidine and Impotence
| Article | Year |
|---|---|
Antiandrogen effects of ulcer drug averted with experimental agent.
Topics: Androgen Antagonists; Cimetidine; Erectile Dysfunction; Furans; Guanidines; Humans; Male; Peptic Ulc | 1982 |
Epigastric pain and HBP after biliary disease.
Topics: Abdomen; Biliary Tract Diseases; Cimetidine; Duodenal Ulcer; Erectile Dysfunction; Humans; Male; Mid | 1983 |
[Andrologic anomalies in various gastrointestinal diseases].
Topics: Cimetidine; Crohn Disease; Cystic Fibrosis; Erectile Dysfunction; Estradiol; Gastrointestinal Diseas | 1983 |
Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states.
Topics: Adult; Breast; Cimetidine; Erectile Dysfunction; Gastric Acid; Guanidines; Gynecomastia; Humans; Mal | 1983 |
Endocrine aspects of impotence.
Topics: Antihypertensive Agents; Cimetidine; Endocrine System Diseases; Erectile Dysfunction; Estrogens; Gon | 1981 |
Male sexual dysfunction during treatment with cimetidine.
Topics: Adult; Cimetidine; Duodenal Ulcer; Erectile Dysfunction; Guanidines; Humans; Male; Middle Aged | 1979 |
Male sexual dysfunction and cimetidine.
Topics: Adult; Aged; Cimetidine; Erectile Dysfunction; Guanidines; Humans; Male; Middle Aged | 1979 |
Male sexual dysfunction during treatment with cimetidine.
Topics: Cimetidine; Erectile Dysfunction; Guanidines; Histamine; Humans; Male; Penis | 1979 |
Impotence on cimetidine treatment.
Topics: Adult; Cimetidine; Duodenal Ulcer; Erectile Dysfunction; Guanidines; Humans; Male | 1979 |
[Can ulcer treatment with cimetidine and other H2 receptor antagonists induce sexual dysfunctions (impotence) and other endocrine disorders?].
Topics: Amenorrhea; Cimetidine; Erectile Dysfunction; Female; Gynecomastia; Humans; Male; Peptic Ulcer; Risk | 1991 |
[Adverse clinico-humoral manifestations in ulcer patients treated with cimetidine. Our experience in 488 patients].
Topics: Cimetidine; Drug Eruptions; Duodenal Ulcer; Erectile Dysfunction; Galactorrhea; Gastrointestinal Dis | 1988 |
Gynaecomastia, galactorrhoea and impotence--the uncommon side effects of cimetidine therapy.
Topics: Adult; Cimetidine; Erectile Dysfunction; Female; Galactorrhea; Gynecomastia; Humans; Lactation Disor | 1987 |
Male sexual dysfunction due to cimetidine.
Topics: Cimetidine; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Middle Aged | 1986 |
Prolactin and the hypothalamic-pituitary-testicular axis in cimetidine-treated men.
Topics: Adult; Cimetidine; Erectile Dysfunction; Follicle Stimulating Hormone; Gynecomastia; Humans; Hypotha | 1985 |
Post-marketing surveillance of the safety of cimetidine: twelve-month morbidity report.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cimetidine; Drug Interactions; Erectile Dysfunctio | 1985 |