cimetidine has been researched along with Hypotension, Orthostatic in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| "Alfuzosin is a new alpha 1-adrenoceptor antagonist particularly effective in the symptomatic treatment of benign prostatic hypertrophy (BPH)." | 2.67 | The effect of cimetidine on the pharmacokinetics of single oral doses of alfuzosin. ( Bianchetti, G; Desager, JP; Harvengt, C; Rosenzweig, P, 1993) |
| "There was no evidence of causes for the anaphylactic reactions over a two and a half year period." | 1.27 | Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. ( Greenberger, PA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
| Greenberger, PA | 1 |
| Desager, JP | 1 |
| Harvengt, C | 1 |
| Bianchetti, G | 1 |
| Rosenzweig, P | 1 |
| Yoshikawa, H | 1 |
| Kawai, K | 1 |
| Inoue, S | 1 |
| Murayama, Y | 1 |
| Kuzuya, N | 1 |
| Fujita, T | 1 |
| Koide, Y | 1 |
| Yamashita, K | 1 |
| Yoshizawa, K | 1 |
| Mizusawa, H | 1 |
1 trial available for cimetidine and Hypotension, Orthostatic
| Article | Year |
|---|---|
The effect of cimetidine on the pharmacokinetics of single oral doses of alfuzosin.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Cimetidine; Dose-Response Relationship, D | 1993 |
3 other studies available for cimetidine and Hypotension, Orthostatic
| Article | Year |
|---|---|
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobuline | 1984 |
[A case of diabetic orthostatic hypotension effectively managed with L-dops (L-threo-3,4-dihydroxyphenylserine)].
Topics: Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Droxidopa; Humans; Hypotension, Orthos | 1987 |