cimetidine has been researched along with Hypocalcemia in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although use of histamine H2 antagonists for chronic treatment of primary hyperparathyroidism (PHP) is ineffective, pretreatment with cimetidine has been reported to reduce the incidence of postoperative hypocalcemia in patients with PHP undergoing neck exploratory operation." | 9.07 | Failure of cimetidine to reduce postoperative hypocalcemia in patients with primary hyperparathyroidism undergoing neck exploratory operation. ( Clark, JR; Georgitis, WJ; Merenich, JA, 1993) |
| "Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism." | 5.27 | The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983) |
| "Although use of histamine H2 antagonists for chronic treatment of primary hyperparathyroidism (PHP) is ineffective, pretreatment with cimetidine has been reported to reduce the incidence of postoperative hypocalcemia in patients with PHP undergoing neck exploratory operation." | 5.07 | Failure of cimetidine to reduce postoperative hypocalcemia in patients with primary hyperparathyroidism undergoing neck exploratory operation. ( Clark, JR; Georgitis, WJ; Merenich, JA, 1993) |
| "Lastly, the nonspecific arrhythmias associated with endocrine disturbances are outlined." | 2.37 | Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances. ( Commerford, PJ; Lloyd, EA, 1984) |
| "Acute hypocalcemia is generally caused by a sudden drop in serum calcium ion and presents with a mild or severe form of tetany." | 1.91 | Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report. ( Bezabhe, WM; Bezabih, YM; Bimrew, MA, 2023) |
| "Cimetidine has been shown to lower circulating PTH levels effectively by causing an intraglandular rearrangement of PTH peptides in human parathyroid tissue in instances of primary hyperparathyroidism." | 1.27 | The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation. ( Ackroyd, FW; Garcia, M; Minervini, D; Seiden, EF; Sherwood, JK; Willis, IH, 1983) |
| "Cimetidine may have been responsible for the observed complications due to its effect on serum parathyroid hormone level." | 1.26 | Effect of cimetidine on serum calcium levels in an elderly patient. ( Edwards, H; King, TC; Zinberg, J, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Bezabih, YM | 1 |
| Bimrew, MA | 1 |
| Bezabhe, WM | 1 |
| Pettengell, KE | 1 |
| Grayson, MJ | 1 |
| Commerford, PJ | 1 |
| Lloyd, EA | 1 |
| Sherwood, JK | 1 |
| Ackroyd, FW | 1 |
| Garcia, M | 1 |
| Willis, IH | 1 |
| Minervini, D | 1 |
| Seiden, EF | 1 |
| Beccari, G | 1 |
| Del Noce, A | 1 |
| Grossi, E | 1 |
| Edwards, H | 1 |
| Zinberg, J | 1 |
| King, TC | 1 |
| Ma, J | 1 |
| Aou, S | 1 |
| Matsui, H | 1 |
| Hori, T | 1 |
| Merenich, JA | 1 |
| Georgitis, WJ | 1 |
| Clark, JR | 1 |
| Cabrera-Saadoun, MC | 1 |
| Sauveur, B | 1 |
1 review available for cimetidine and Hypocalcemia
| Article | Year |
|---|---|
Arrhythmias in patients with drug toxicity, electrolyte, and endocrine disturbances.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Agents; Cimetidine; Digitalis Glycoside | 1984 |
1 trial available for cimetidine and Hypocalcemia
| Article | Year |
|---|---|
Failure of cimetidine to reduce postoperative hypocalcemia in patients with primary hyperparathyroidism undergoing neck exploratory operation.
Topics: Adult; Cimetidine; Double-Blind Method; Female; Humans; Hyperparathyroidism; Hypocalcemia; Male; Mid | 1993 |
7 other studies available for cimetidine and Hypocalcemia
| Article | Year |
|---|---|
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spa | 2023 |
Cimetidine and hyperparathyroidism.
Topics: Calcium; Cimetidine; Guanidines; Humans; Hyperparathyroidism; Hypocalcemia; Male; Parathyroid Hormon | 1980 |
The preoperative use of cimetidine as a means of preventing symptomatic hypocalcemia following a parathyroid operation.
Topics: Adenoma; Calcium; Cimetidine; Humans; Hypocalcemia; Parathyroid Glands; Parathyroid Hormone; Parathy | 1983 |
[Hypocalcemia during cimetidine and carbenoxolone treatment].
Topics: Carbenoxolone; Cimetidine; Glycyrrhetinic Acid; Guanidines; Humans; Hypocalcemia; Male | 1982 |
Effect of cimetidine on serum calcium levels in an elderly patient.
Topics: Aged; Calcium Gluconate; Cimetidine; Colonic Diseases; Diverticulitis, Colonic; Female; Guanidines; | 1981 |
Gastric vagus mediates immobilization-induced hypocalcemia in rats.
Topics: Animals; Atropine Derivatives; Cimetidine; Female; Gastrins; Hypocalcemia; Immobilization; Rats; Rat | 1993 |
Histamine-induced hyperphosphatemia and hypocalcemia in the laying hen.
Topics: Animals; Calcium; Chickens; Cimetidine; Female; Histamine; Hypocalcemia; Oviposition; Phosphates; Pr | 1986 |