cimetidine has been researched along with Hyperplasia in 13 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable." | 7.67 | The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987) |
| "The potential mucosal protective effects of a liquid sucralfate preparation and the histamine (H2)-antagonist cimetidine on acid-induced esophagitis were studied." | 7.67 | Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. ( Castell, DO; Clark, S; Geisinger, KR; Katz, PO; Wu, WC, 1987) |
| "An elevated type of gastric ulcer scar (EUS) (A) was noted in 8 out of 227 ulcer patients treated with cimetidine." | 7.67 | An elevated type of gastric ulcer scar in patients treated with cimetidine. ( Ito, S; Kishi, S; Matsumura, M; Mizobuchi, T; Mori, H; Ohura, M; Shimizu, I, 1986) |
| "A density study of the antral gastrin-producing cells has been performed, before and after eight weeks of treatment with a histamine H2-receptor antagonist (cimetidine 1 g per day), in a series of 38 patients suffering from chronic duodenal ulcer." | 7.66 | The antral gastrin-producing cells in duodenal ulcer patients. A density study before and during treatment with cimetidine. ( Christiansen, LA; Jensen, KB; Nielsen, HO, 1980) |
| "HCl/hr." | 5.26 | A case of Brunner's glands hyperplasia with diarrhea responsive to cimetidine. ( Spellberg, MA; Vucelic, B, 1980) |
| "The effect of cimetidine on basal and histamine-induced PTH secretion was tested using single cell suspensions obtained from (a) primary parathyroid adenomas, and (b) secondary hyperplastic parathyroid tissue from patients undergoing chronic hemodialysis." | 3.67 | Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro. ( Beyer, J; Krause, U; Rothmund, M; Schärfe, T; Wagner, PK, 1984) |
| "The effects of combined administration of cimetidine and tetragastrin on gastric acid secretion, the labeling index of the gastric mucosa, and the incidence of gastric adenocarcinomas induced by N-methyl-N'-nitro-N-nitrosoguanidine were investigated in inbred Wistar rats." | 3.67 | Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. ( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M; Yamamoto, R; Yamamura, H, 1988) |
| "Recent evidence suggests that cimetidine given pre-operatively in primary hyperparathyroidism (1 degree HPT) might cause structural changes in parathyroid glands, while its suppressive effects on the disease are disputable." | 3.67 | The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism. ( Ikkos, DG; Nikou, AD; Pappas, AD; Singhellakis, PN; Sklivagou, NG; Sotsiou, FC; Vambouka, C, 1987) |
| "The potential mucosal protective effects of a liquid sucralfate preparation and the histamine (H2)-antagonist cimetidine on acid-induced esophagitis were studied." | 3.67 | Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. ( Castell, DO; Clark, S; Geisinger, KR; Katz, PO; Wu, WC, 1987) |
| "An elevated type of gastric ulcer scar (EUS) (A) was noted in 8 out of 227 ulcer patients treated with cimetidine." | 3.67 | An elevated type of gastric ulcer scar in patients treated with cimetidine. ( Ito, S; Kishi, S; Matsumura, M; Mizobuchi, T; Mori, H; Ohura, M; Shimizu, I, 1986) |
| "A density study of the antral gastrin-producing cells has been performed, before and after eight weeks of treatment with a histamine H2-receptor antagonist (cimetidine 1 g per day), in a series of 38 patients suffering from chronic duodenal ulcer." | 3.66 | The antral gastrin-producing cells in duodenal ulcer patients. A density study before and during treatment with cimetidine. ( Christiansen, LA; Jensen, KB; Nielsen, HO, 1980) |
| "Relapses were re-treated with omeprazole 40 mg; upon rehealing, patients were put on maintenance omeprazole 20 mg daily for up to 4." | 2.68 | Histamine H2 receptor antagonist-refractory oesophagitis: the efficacy of long-term omeprazole maintenance treatment. ( Bardhan, KD; Bishop, A; Brooks, A; Cherian, P; D'Silva, J; Gillon, KR; Jones, RB; Manek, S; Morris, P; Parkin, S; Patterson, J; Polak, J; Thompson, M; Vaishnavi, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smedley, HM | 1 |
| Wagner, PK | 1 |
| Krause, U | 1 |
| Schärfe, T | 1 |
| Beyer, J | 1 |
| Rothmund, M | 1 |
| McCarthy, DM | 1 |
| Nielsen, HO | 1 |
| Jensen, KB | 1 |
| Christiansen, LA | 1 |
| Marks, R | 1 |
| Dykes, PJ | 1 |
| Tan, CY | 1 |
| Spellberg, MA | 1 |
| Vucelic, B | 1 |
| Low, JD | 1 |
| House, AK | 1 |
| Norman, PE | 1 |
| Bardhan, KD | 1 |
| Cherian, P | 1 |
| Jones, RB | 1 |
| Vaishnavi, A | 1 |
| Manek, S | 1 |
| Bishop, A | 1 |
| Polak, J | 1 |
| Brooks, A | 1 |
| Morris, P | 1 |
| Thompson, M | 1 |
| D'Silva, J | 1 |
| Parkin, S | 1 |
| Patterson, J | 1 |
| Gillon, KR | 1 |
| Jewell, LD | 1 |
| Yacoub, W | 1 |
| Salkie, ML | 1 |
| Sherbaniuk, R | 1 |
| Walker, K | 1 |
| Mahachai, V | 1 |
| Kirdeikis, P | 1 |
| Simpson, I | 1 |
| Zuk, L | 1 |
| Brunet, MK | 1 |
| Tatsuta, M | 1 |
| Iishi, H | 1 |
| Yamamura, H | 1 |
| Baba, M | 1 |
| Yamamoto, R | 1 |
| Taniguchi, H | 1 |
| Sotsiou, FC | 1 |
| Singhellakis, PN | 1 |
| Nikou, AD | 1 |
| Pappas, AD | 1 |
| Vambouka, C | 1 |
| Sklivagou, NG | 1 |
| Ikkos, DG | 1 |
| Clark, S | 1 |
| Katz, PO | 1 |
| Wu, WC | 1 |
| Geisinger, KR | 1 |
| Castell, DO | 1 |
| Ito, S | 1 |
| Mizobuchi, T | 1 |
| Shimizu, I | 1 |
| Ohura, M | 1 |
| Matsumura, M | 1 |
| Kishi, S | 1 |
| Mori, H | 1 |
1 review available for cimetidine and Hyperplasia
| Article | Year |
|---|---|
The place of surgery in the Zollinger-Ellison syndrome.
Topics: Cimetidine; Gastrectomy; Gastric Juice; Gastrins; Humans; Hyperplasia; Neoplasm Metastasis; Postoper | 1980 |
1 trial available for cimetidine and Hyperplasia
| Article | Year |
|---|---|
Histamine H2 receptor antagonist-refractory oesophagitis: the efficacy of long-term omeprazole maintenance treatment.
Topics: Adult; Aged; Biopsy; Cimetidine; Drug Administration Schedule; Drug Resistance; Enzyme Inhibitors; E | 1997 |
11 other studies available for cimetidine and Hyperplasia
| Article | Year |
|---|---|
Malignant breast change in man given two drugs associated with breast hyperplasia.
Topics: Aged; Breast; Cimetidine; Doxepin; Drug Synergism; Guanidines; Humans; Hyperplasia; Male | 1981 |
Effect of cimetidine on basal and histamine-induced secretion of parathyroid hormone in vitro.
Topics: Adenoma; Cimetidine; Dose-Response Relationship, Drug; Histamine; Humans; Hyperparathyroidism; Hyper | 1984 |
The antral gastrin-producing cells in duodenal ulcer patients. A density study before and during treatment with cimetidine.
Topics: Adult; Aged; Cell Division; Cimetidine; Duodenal Ulcer; Female; Gastric Juice; Gastrins; Humans; Hyp | 1980 |
Histamine and epidermal proliferation.
Topics: Adult; Cell Division; Chlorpheniramine; Cimetidine; Female; Histamine; Humans; Hyperplasia; Male; Mi | 1982 |
A case of Brunner's glands hyperplasia with diarrhea responsive to cimetidine.
Topics: Brunner Glands; Cimetidine; Diarrhea; Duodenum; Female; Guanidines; Humans; Hyperplasia; Middle Aged | 1980 |
Role of cimetidine in the prevention of intimal hyperplasia in rat carotid artery.
Topics: Animals; Carotid Arteries; Cell Division; Cimetidine; Histamine H2 Antagonists; Hyperplasia; Male; M | 1996 |
Enprostil reduces G-cell hyperplasia and hypergastrinemia in duodenal ulcer.
Topics: Adult; Cimetidine; Duodenal Ulcer; Enprostil; Gastric Acid; Gastrins; Humans; Hydrogen-Ion Concentra | 1987 |
Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Topics: Adenocarcinoma; Animals; Cimetidine; DNA; Gastric Acid; Gastric Mucosa; Gastrins; Hyperplasia; Male; | 1988 |
The effect of cimetidine on parathyroid function and histopathology in primary hyperparathyroidism.
Topics: Adenoma; Adolescent; Adult; Aged; Calcium; Cimetidine; Female; Humans; Hyperparathyroidism; Hyperpla | 1987 |
Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis.
Topics: Animals; Cats; Cimetidine; Endoscopy; Epithelium; Esophagitis; Esophagus; Fiber Optic Technology; Hy | 1987 |
An elevated type of gastric ulcer scar in patients treated with cimetidine.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix; Cimetidine; Female; Gastroscopy; Humans; | 1986 |