cimetidine has been researched along with Hyperparathyroidism, Secondary in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hyperparathyroidism, Secondary: Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the acute effect of histamine H2-receptor blockade with cimetidine on PTH concentrations and its endogenous biological activity, we studied the effect of iv administration of cimetidine (50-mg bolus followed by 500 mg/60 min infusion) in normal subjects and patients with primary and secondary hyperparathyroidism." | 7.67 | Effect of acute cimetidine administration on indices of parathyroid hormone action in healthy subjects and patients with primary and secondary hyperparathyroidism. ( Bernheim, J; Glaser, B; Gonda, M; Kraiem, Z; Rotem, M; Sheinfeld, M, 1984) |
| "Cimetidine treatment caused no changes in serum calcium, phosphorus, or iPTH or in urinary cAMP (expressed as nanomoles per g creatinine)." | 5.26 | Cimetidine treatment of azotemic secondary hyperparathyroidism. ( Heath, H; Johnson, WJ; Robinson, MF, 1982) |
| "To evaluate the acute effect of histamine H2-receptor blockade with cimetidine on PTH concentrations and its endogenous biological activity, we studied the effect of iv administration of cimetidine (50-mg bolus followed by 500 mg/60 min infusion) in normal subjects and patients with primary and secondary hyperparathyroidism." | 3.67 | Effect of acute cimetidine administration on indices of parathyroid hormone action in healthy subjects and patients with primary and secondary hyperparathyroidism. ( Bernheim, J; Glaser, B; Gonda, M; Kraiem, Z; Rotem, M; Sheinfeld, M, 1984) |
| "Cimetidine treatment caused no changes in serum calcium, phosphorus, or iPTH or in urinary cAMP (expressed as nanomoles per g creatinine)." | 1.26 | Cimetidine treatment of azotemic secondary hyperparathyroidism. ( Heath, H; Johnson, WJ; Robinson, MF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cunningham, J | 2 |
| Segre, GV | 1 |
| Slatopolsky, E | 2 |
| Avioli, LV | 1 |
| Segre, G | 1 |
| Glaser, B | 1 |
| Kraiem, Z | 1 |
| Rotem, M | 1 |
| Gonda, M | 1 |
| Bernheim, J | 1 |
| Sheinfeld, M | 1 |
| Robinson, MF | 1 |
| Johnson, WJ | 1 |
| Heath, H | 1 |
| Kovarik, J | 1 |
| Graf, H | 1 |
| Woloszczuk, W | 1 |
| Stummvoll, HK | 1 |
| Jacob, AI | 3 |
| Canterbury, JM | 1 |
| Gavellas, G | 1 |
| Lambert, PW | 1 |
| Bourgoignie, JJ | 3 |
| Windeck, R | 1 |
| Benker, G | 1 |
| Hoff, HG | 1 |
| Reinwein, D | 1 |
| Makdassi, R | 1 |
| Decourcelle, PH | 1 |
| Moriniere, P | 1 |
| Coevoet, B | 1 |
| de Fremont, JF | 1 |
| Kassouf, J | 1 |
| Roussel, A | 1 |
| Gheerbrand, JD | 1 |
| Andrejak, M | 1 |
| Fournier, A | 1 |
| Lanier, D | 2 |
| Canterbury, J | 1 |
| Favre, H | 1 |
| Fiore, CE | 1 |
| Lunetta, M | 1 |
| Kanis, JA | 1 |
| Antonucci, F | 1 |
| Gropuzzo, M | 1 |
| Messa, PG | 1 |
| Montanaro, D | 1 |
| Adorati, M | 1 |
| Paviotti, G | 1 |
| Favazza, A | 1 |
| Susanna, F | 1 |
| Zilli, M | 1 |
| Mioni, G | 1 |
1 trial available for cimetidine and Hyperparathyroidism, Secondary
| Article | Year |
|---|---|
[Cimetidine in the treatment of secondary hyperparathyroidism in uremia treated with hemodialysis].
Topics: Adult; Calcium; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Humans; Hyperparathyroidism, | 1985 |
11 other studies available for cimetidine and Hyperparathyroidism, Secondary
| Article | Year |
|---|---|
Effect of histamine H2-receptor blockade on parathyroid status in normal and uraemic man.
Topics: Adult; Cimetidine; Female; Humans; Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Male; Pa | 1984 |
Histamine H2 receptor blockade in patients with hyperparathyroidism.
Topics: Cimetidine; Humans; Hyperparathyroidism; Hyperparathyroidism, Secondary; Parathyroid Hormone; Raniti | 1984 |
Effect of acute cimetidine administration on indices of parathyroid hormone action in healthy subjects and patients with primary and secondary hyperparathyroidism.
Topics: Adult; Aged; Calcium; Cimetidine; Cyclic AMP; Female; Humans; Hyperparathyroidism; Hyperparathyroidi | 1984 |
Cimetidine treatment of azotemic secondary hyperparathyroidism.
Topics: Adult; Cimetidine; Creatinine; Cyclic AMP; Female; Guanidines; Humans; Hyperparathyroidism, Secondar | 1982 |
Cimetidine in secondary hyperparathyroidism.
Topics: Cimetidine; Guanidines; Humans; Hyperparathyroidism, Secondary; Uremia | 1982 |
Reversal of secondary hyperparathyroidism by cimetidine in chronically uremic dogs.
Topics: Animals; Calcium; Cimetidine; Dogs; Female; Guanidines; Homeostasis; Hyperparathyroidism, Secondary; | 1981 |
[Cimetidine therapy of hyperparathyroidism?].
Topics: Calcium; Cimetidine; Guanidines; Humans; Hyperparathyroidism; Hyperparathyroidism, Secondary; Parath | 1981 |
Blockers of beta and H2 receptors and secondary hyperparathyroidism in uraemia.
Topics: Adult; Aged; Atenolol; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism, Secondary; Male; | 1981 |
Reduction by cimetidine of serum parathyroid hormone levels in uremic patients.
Topics: Adult; Aged; Calcium; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism, Secondary; Male; | 1980 |
Cimetidine therapy for severe hypercalcemia in two chronic hemodialysis patients.
Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; Middle | 1980 |
Long-term effects of histamine H2-receptor antagonists on serum parathyroid hormone in chronic renal failure.
Topics: Adult; Alkaline Phosphatase; Calcium; Calcium-Binding Proteins; Cimetidine; Female; Humans; Hyperpar | 1985 |