cimetidine has been researched along with Hyperlipidemia, Familial Combined in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hyperlipidemia, Familial Combined: A type of familial lipid metabolism disorder characterized by a variable pattern of elevated plasma CHOLESTEROL and/or TRIGLYCERIDES. Multiple genes on different chromosomes may be involved, such as the major late transcription factor (UPSTREAM STIMULATORY FACTORS) on CHROMOSOME 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 35-yr-old man with moderate hypertriglyceridemia, associated with a positive family history for hyperlipidemia, developed chylomicronemia with abdominal pain, muscle pain, and splenomegaly while being treated with cimetidine for a duodenal ulcer." | 3.67 | Chylomicronemia induced by cimetidine. ( Brunzell, JD; Iverius, PH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iverius, PH | 1 |
| Brunzell, JD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia[NCT00005313] | 450 participants (Actual) | Observational | 2001-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for cimetidine and Hyperlipidemia, Familial Combined
| Article | Year |
|---|---|
Chylomicronemia induced by cimetidine.
Topics: Adult; Cholesterol; Chylomicrons; Cimetidine; Duodenal Ulcer; Humans; Hyperlipidemia, Familial Combi | 1985 |