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cimetidine and Hirsutism

cimetidine has been researched along with Hirsutism in 13 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine (Tagamet, Smith Klein, Brussels, Belgium) the histamine receptor type 2 blocker, has been suggested as a possible treatment of hirsutism."9.06Treatment of hirsutism with cimetidine: a prospective randomized controlled trial. ( Abramovici, H; Calderon, I; Dirnfeld, M; Lioz, H; Lissak, A; Sorokin, Y, 1989)
"We evaluated the efficacy of long-term cimetidine in treating hirsutism by monitoring four indices: subjective hair removal practice, grading of hair growth by the Lorenzo scale, photography, and hair weight measurement."7.68Treatment of hirsutism with cimetidine. ( Golditch, IM; Price, VH, 1990)
"Cimetidine (Tagamet, Smith Klein, Brussels, Belgium) the histamine receptor type 2 blocker, has been suggested as a possible treatment of hirsutism."5.06Treatment of hirsutism with cimetidine: a prospective randomized controlled trial. ( Abramovici, H; Calderon, I; Dirnfeld, M; Lioz, H; Lissak, A; Sorokin, Y, 1989)
" Cyproterone acetate allows differentiated treatment according to the various grades of hirsutism by modification of dosage and application."1.27[The concept of the causal therapy of hirsutism]. ( Schmidt, JB, 1986)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Braithwaite, SS1
Jabamoni, R1
De Pedrini, P1
Suraci, C1
Costa, C1
Grandesso, R1
Spandri, P1
Gangemi, M1
Nardelli, GB1
Ambrosio, GB1
Conte, G1
De Salvia, D1
Meneghetti, G1
Michel, B1
Sultan, C1
Meynadier, J1
Presl, J1
Vigersky, RA1
Mehlman, I1
Glass, AR1
Smith, CE1
Küçükkömürcü, S1
Kimya, Y1
Bilici, K1
Golditch, IM1
Price, VH1
Lissak, A1
Sorokin, Y1
Calderon, I1
Dirnfeld, M1
Lioz, H1
Abramovici, H1
Schmidt, JB1
Kovács, I1
Buckshee, K1
Ahuja, MM1
Morris, DV1

Reviews

2 reviews available for cimetidine and Hirsutism

ArticleYear
Hirsutism.
    Archives of dermatology, 1983, Volume: 119, Issue:4

    Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Androgen Antagonists; And

1983
Hirsutism.
    Clinics in obstetrics and gynaecology, 1985, Volume: 12, Issue:3

    Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Androgens; Cimetidine

1985

Trials

1 trial available for cimetidine and Hirsutism

ArticleYear
Treatment of hirsutism with cimetidine: a prospective randomized controlled trial.
    Fertility and sterility, 1989, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Cimetidine; Clinical Trials as Topic; Dehydroepiandrosterone; Female; Hirsutism;

1989

Other Studies

10 other studies available for cimetidine and Hirsutism

ArticleYear
[Therapy of female hirsutism: current status and new findings].
    La Clinica terapeutica, 1983, Mar-31, Volume: 104, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Androgens; Bromocrip

1983
Hormonal changes and hair growth during treatment of hirsutism with cimetidine.
    Clinical and experimental obstetrics & gynecology, 1984, Volume: 11, Issue:3

    Topics: 17-Ketosteroids; Adult; Cimetidine; Estradiol; Female; Follicle Stimulating Hormone; Hair; Hirsutism

1984
[Failure of the treatment of idiopathic hirsutism with cimetidine].
    Annales de dermatologie et de venereologie, 1983, Volume: 110, Issue:2

    Topics: Adolescent; Adult; Cimetidine; Female; Guanidines; Hirsutism; Humans; Receptors, Androgen

1983
[Cimetidine--a new treatment for hirsutism?].
    Ceskoslovenska gynekologie, 1981, Volume: 46, Issue:7

    Topics: Cimetidine; Female; Guanidines; Hirsutism; Humans

1981
Treatment of hirsute women with cimetidine.
    The New England journal of medicine, 1980, Oct-30, Volume: 303, Issue:18

    Topics: Adolescent; Adult; Cimetidine; Female; Guanidines; Hirsutism; Humans; Polycystic Ovary Syndrome

1980
The effects of cimetidine on serum testosterone levels.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1993, Volume: 42, Issue:3

    Topics: Cimetidine; Female; Hirsutism; Humans; Testosterone

1993
Treatment of hirsutism with cimetidine.
    Obstetrics and gynecology, 1990, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Cimetidine; Female; Hirsutism; Humans; Middle Aged

1990
[The concept of the causal therapy of hirsutism].
    Zeitschrift fur Hautkrankheiten, 1986, Feb-15, Volume: 61, Issue:4

    Topics: Cimetidine; Cyproterone; Cyproterone Acetate; Hirsutism; Humans; Medroxyprogesterone; Medroxyprogest

1986
Attempts with cimetidine (Histodil) in non-steroid treatment of hirsutism.
    Therapia Hungarica (English edition), 1987, Volume: 35, Issue:2

    Topics: Adult; Cimetidine; Female; Hirsutism; Humans

1987
Therapeutic evaluation of effectiveness of cimetidine in the treatment of hirsutism.
    The Indian journal of medical research, 1985, Volume: 82

    Topics: Adolescent; Adult; Child; Cimetidine; Female; Hirsutism; Humans

1985