cimetidine has been researched along with Hepatic Encephalopathy in 8 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine kinetics were followed in 16 cirrhotic patients after a single IV 300-mg dose." | 5.27 | Hepatic encephalopathy and altered cimetidine kinetics. ( Bernhard, H; Schentag, JJ; Ziemniak, JA, 1983) |
| "Cimetidine kinetics were followed in 16 cirrhotic patients after a single IV 300-mg dose." | 1.27 | Hepatic encephalopathy and altered cimetidine kinetics. ( Bernhard, H; Schentag, JJ; Ziemniak, JA, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Triger, DR | 1 |
| Goepel, JR | 1 |
| Slater, DN | 1 |
| Underwood, JC | 1 |
| Mörl, M | 1 |
| Ziemniak, JA | 1 |
| Bernhard, H | 1 |
| Schentag, JJ | 1 |
| Wienbeck, M | 1 |
| Chamuleau, RA | 1 |
| Bode, JC | 1 |
| Reiter, HJ | 1 |
| Chotkowski, L | 1 |
2 reviews available for cimetidine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Treatment of acute hepatic encephalopathy.
Topics: Acid-Base Imbalance; Acute Disease; Adrenal Cortex Hormones; Antacids; Anti-Bacterial Agents; Blood | 1979 |
[Exogenous hepatic coma--standard therapy with amino acid solutions].
Topics: Alkalosis; Amino Acids; Cimetidine; Energy Intake; Fluid Therapy; Hepatic Encephalopathy; Humans; La | 1979 |
6 other studies available for cimetidine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Systemic candidiasis complicating acute hepatic failure in patients treated with cimetidine.
Topics: Acute Disease; Adult; Candidiasis; Cimetidine; Esophagus; Female; Gastric Juice; Guanidines; Hepatic | 1981 |
[Therapy of hepatic coma].
Topics: Anti-Bacterial Agents; Bromocriptine; Cimetidine; Dietary Proteins; Hepatic Encephalopathy; Humans; | 1984 |
Hepatic encephalopathy and altered cimetidine kinetics.
Topics: Adult; Cimetidine; Female; Guanidines; Hepatic Encephalopathy; Humans; Kinetics; Liver Cirrhosis; Li | 1983 |
[The treatment of hepatic emergencies].
Topics: Cimetidine; Female; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Lactulose; Liver Di | 1979 |
Heroic treatment for fulminant hepatic failure?
Topics: Cimetidine; Critical Care; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Prognosis | 1977 |
Etiologic mechanism questioned.
Topics: Cimetidine; Guanidines; Hepatic Encephalopathy; Humans; Liver Cirrhosis | 1979 |